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Chlorothiazide

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generic Diuril

Chlorothiazide is a medication primarily used to manage high blood pressure and fluid retention (edema). As a thiazide diuretic, or "water pill," it promotes increased urination, helping the body eliminate excess salt, water, and certain electrolytes like sodium and potassium. This action aids in lowering blood pressure and reducing swelling. By effectively managing these conditions, Chlorothiazide can help prevent complications such as strokes, heart attacks, and kidney problems. Additionally, it can alleviate symptoms associated with edema, such as difficulty breathing and swelling in areas like the ankles, feet, hands, and abdomen, thereby improving kidney function and overall comfort.
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Chlorothiazide WarningsChlorothiazide Side EffectsChlorothiazide InteractionsFAQs

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100GM of 1, Chlorothiazide (1 Bottle)

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The average cost for 1 Bottle of Chlorothiazide (generic Diuril) at 100GM of 1 is $2551.8 with a free coupon. This is 27.64% off the average retail price of $9233.65
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100GM of 11 Bottle$2551.8$2551.8

Chlorothiazide Warnings

When using chlorothiazide, it is essential to be aware of certain safety information and warnings. These highlight potential risks and precautions to consider. Please review these points carefully and consult your healthcare provider with any questions or concerns:

  • Dehydration and Electrolyte Imbalance: Excessive use of chlorothiazide can lead to increased urination, which might cause dehydration and disturb electrolyte balance, notably sodium, potassium, magnesium, or chloride. Be alert for symptoms such as dry mouth, weakness, fatigue, dizziness, muscle pain or cramps, increased heart rate, vomiting, or nausea. These effects are more likely if you have impaired kidney function, an existing electrolyte imbalance, or are exposed to hot weather.

  • Low Blood Pressure: This medication lowers blood pressure, which might result in lightheadedness or dizziness. The effects can be pronounced if combined with alcohol or other blood pressure-lowering drugs. It is advisable to limit alcohol consumption while using chlorothiazide.

  • Worsening Kidney Issues: Chlorothiazide has the potential to impair kidney function. Regular blood tests are recommended to monitor kidney health before starting the medication and at least annually thereafter, especially if you have a history of kidney problems.

  • Elevated Blood Sugar Levels: There is a risk of increased blood sugar levels with chlorothiazide use. Individuals with diabetes should monitor their blood sugar more frequently, and this should be discussed with your healthcare provider.

  • Gout: This medication may elevate uric acid levels, potentially triggering or aggravating gout. This risk is higher if you have a history of gout or current kidney issues.

  • Parathyroid Disease: Chlorothiazide can affect calcium excretion, which may impact the parathyroid gland. Discuss any concerns with your healthcare provider.

In case of an overdose or severe side effects, seek immediate medical attention. Always follow your healthcare provider's instructions regarding medication use and interactions with other substances.

Chlorothiazide Side Effects

Common side effects:

  • Dizziness
  • Low blood pressure
  • Changes in electrolyte levels
  • Increased sensitivity to sunlight

Less common but important to monitor:

  • High blood sugar levels
  • Kidney failure
  • Difficulties with sexual performance (e.g., erectile dysfunction)

Chlorothiazide Interactions

Keep a list of all the products you use (such as prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Some products that may interact with this drug are: dofetilide, lithium. Some products have ingredients that could raise your blood pressure or worsen your swelling. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). This product may interfere with certain lab tests. Make sure lab personnel and all your doctors know you use this drug.
Chlorothiazide FAQs
What is drug chlorothiazide used for?

Chlorothiazide is used to treat high blood pressure and fluid retention (edema) associated with conditions such as heart failure, liver disease, or kidney disorders. It is a diuretic, often referred to as a "water pill," that helps the body get rid of excess salt and water by increasing urine production.

Chlorothiazide is not a potassium-sparing diuretic. It is a thiazide diuretic, which can lead to the loss of potassium in the urine.

The first choice diuretic for hypertension is typically a thiazide diuretic, such as hydrochlorothiazide or chlorthalidone. These medications are often recommended as initial therapy for managing high blood pressure due to their effectiveness and favorable side effect profile.

Chlorothiazide and hydrochlorothiazide are not the same, although they are both thiazide diuretics used to treat high blood pressure and fluid retention. They differ in their chemical structure and potency, with hydrochlorothiazide generally being more potent than chlorothiazide.

Chlorothiazide is a potassium-wasting diuretic. It can lead to a decrease in potassium levels in the body, so monitoring and possibly supplementing potassium may be necessary during its use.

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