Cyclosporine A

Drug Details

Cyclosporine A is a potent immunosuppressant primarily used to prevent organ rejection in transplant recipients and to treat certain autoimmune conditions. It functions by inhibiting calcineurin, an enzyme crucial for activating T-cells, thereby reducing the immune system's response. Common applications include preventing rejection in kidney, liver, and heart transplants, as well as managing severe cases of rheumatoid arthritis and psoriasis that have not responded to other treatments. While effective, cyclosporine A can cause side effects such as high blood pressure, kidney dysfunction, increased risk of infections, and excessive hair growth. Due to its potential for serious adverse effects, careful monitoring by healthcare professionals is essential during treatment.