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Voriconazole

Voriconazole Coupons & Discount Card – Guaranteed Prices from $42.60

generic Vfend

Voriconazole, marketed as Vfend, is an antifungal medication used to treat serious fungal infections in adults and children over 2 years old. This includes conditions like invasive aspergillosis and esophageal candidiasis. Voriconazole belongs to the azole antifungal class and functions by inhibiting the growth of fungi. Initially administered as an intravenous infusion in a hospital setting for severe cases, it may later be prescribed as an oral tablet or suspension to be taken every 12 hours once the patient improves. It is particularly useful for individuals who cannot tolerate or do not respond well to other treatments, addressing infections like candidemia and certain deep tissue infections. Common side effects can include vision changes, nausea, and rash. Always consult healthcare professionals for advice tailored to your specific health needs.
Our coupons are free to use. Before paying, show the pharmacist your Voriconazole savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Voriconazole prices will update based on your prescription needs. Above our Voriconazole coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Voriconazole at the lowest price with our prescription discount card.
Voriconazole WarningsVoriconazole Side EffectsVoriconazole InteractionsFAQs

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200MG, Voriconazole (30 Tablets)

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Voriconazole dosage forms

The average cost for 30 Tablets of Voriconazole (generic Vfend) at 50MG is $15.65 with a free coupon. This is 99% off the average retail price of $1407.3
DosageQuantityPrice fromPer unit
50MG30 Tablets$15.65$0.52
200MG30 Tablets$43.59$1.45

Voriconazole Warnings

The following safety information outlines the essential warnings and precautions for the use of voriconazole (Vfend). It is important to carefully review this information and discuss any concerns with your healthcare provider.

  • Liver Damage: Although uncommon, voriconazole (Vfend) has been linked to liver problems. Your doctor may conduct liver function tests before and during treatment. It is advisable to limit or avoid alcohol to reduce liver damage risk. Seek immediate medical attention if you notice yellowing of the skin or eyes, changes in stool, dark urine, stomach swelling, pain, or confusion. Your doctor may advise discontinuing the medication to prevent further liver injury. Risks include pre-existing liver issues, certain blood cancers, and concurrent use of other liver-affecting medications.

  • Abnormal Heart Rhythm: Voriconazole (Vfend) may cause serious heart rhythm changes, such as QT prolongation. Your risk is heightened by factors like abnormal electrolyte levels, heart rhythm disorders, or concurrent use of medications affecting heart rhythm (e.g., amiodarone, ciprofloxacin). Regular heart monitoring, including ECGs, may be necessary. If you experience chest pounding, breathing difficulties, chest pain, or faintness, seek emergency medical help immediately. Risks include low potassium or magnesium levels, kidney issues, history of heart problems, and use of QT-prolonging medications.

  • Vision Changes: Use of voriconazole (Vfend) may lead to blurred vision, visual changes, and light sensitivity, particularly with use beyond 28 days. An eye examination is recommended if using the medication long-term or if vision changes occur. Avoid nighttime driving and wear sunglasses if bright lights cause discomfort. Consult your doctor if vision issues interfere with daily activities.

  • Allergic Reactions (IV Infusions): Severe allergic reactions can occur, including facial swelling and anaphylaxis. Seek immediate medical help if you experience breathing difficulty, swelling near the eyes, lips, or tongue, or dizziness after taking the medication.

  • Severe Skin Reactions: Rarely, voriconazole (Vfend) can cause serious skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis. If you notice skin changes like rash, blisters, or peeling, accompanied by fever and swollen lymph nodes, seek medical attention promptly.

  • Sun and Light Sensitivity: The medication increases skin sensitivity to sunlight and UV light, increasing the risk of sunburn. Use high-SPF sunscreen and wear protective clothing outside. Avoid prolonged sun exposure.

  • Pregnancy Warning: Voriconazole (Vfend) may cause developmental issues in unborn babies. If you are capable of becoming pregnant, use effective contraception during treatment. Inform your doctor immediately if you are pregnant or planning pregnancy.

  • Low Adrenal Hormone Levels: Some individuals report low adrenal hormone levels with azole antifungals. Symptoms include fatigue, dizziness, and nausea. Notify your doctor if these symptoms occur.

  • Pancreatitis: Inflammation of the pancreas has been reported. Symptoms include stomach pain, nausea, vomiting, and yellowing of the eyes or skin. Report these symptoms to your doctor for evaluation. Risks include recent chemotherapy or stem cell transplantation.

  • Bone and Teeth Issues: Long-term use may lead to bone pain or tooth discoloration. Report these symptoms to your doctor, as discontinuation of the medication may be needed.

  • Kidney Concerns: There have been reports of kidney problems, though it's unclear if voriconazole (Vfend) is the cause. Your doctor may monitor kidney function through lab tests.

Contraindications: Avoid using voriconazole (Vfend) if you are taking certain medications such as pimozide, quinidine, ivabradine, sirolimus, rifampin, carbamazepine, long-acting barbiturates, St. John's Wort, rifabutin, ergot alkaloids, naloxegol, tolvaptan, or lurasidone. Also, avoid if taking efavirenz at doses of 400 mg or higher every 24 hours, ritonavir 400 mg every 12 hours, or during the initial phases of venetoclax treatment for certain cancers due to the risk of tumor lysis syndrome.

Voriconazole Side Effects

Common side effects:

  • Nausea
  • Vomiting
  • Headache
  • Vision changes
  • Rash

Less common but important to monitor:

  • Fever
  • Stomach pain
  • Diarrhea
  • Low blood potassium levels
  • High blood pressure
  • Cough
  • Low platelet count
  • Nosebleeds

Serious side effects:

  • Fast or irregular heartbeat
  • Severe dizziness
  • Fainting
  • Chills
  • High liver enzymes
  • Hallucinations
  • Very serious liver disease
  • Severe allergic reaction

Voriconazole Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Interactions with low risk that usually do not require a change in therapy:

Voriconazole FAQs
What is the drug voriconazole used for?

Voriconazole is an antifungal medication used to treat serious fungal infections, including invasive aspergillosis and infections caused by Candida species. It is often prescribed for patients with weakened immune systems or those who have not responded to other antifungal treatments.

Voriconazole, an antifungal medication, has several potential disadvantages and side effects. These may include:1. Visual Disturbances: Patients may experience changes in vision, such as blurred vision, color vision changes, or increased sensitivity to light.2. Liver Toxicity: There is a risk of liver damage, which may manifest as elevated liver enzymes or more severe liver dysfunction.3. Skin Reactions: Some individuals may develop skin rashes or photosensitivity, increasing the risk of sunburn.4. Neurological Effects: Possible side effects include headache, dizziness, and hallucinations.5. Drug Interactions: Voriconazole can interact with a variety of other medications, potentially altering their effects.6. QT Prolongation: It may cause changes in heart rhythm, specifically prolonging the QT interval, which can be serious.7. Renal Impairment: There is a potential risk of kidney function impairment.Patients should be monitored for these side effects, and any concerns should be discussed with a healthcare provider.

Voriconazole can interact with several medications, and certain drugs should be avoided or used with caution. These include:1. Rifampin and Rifabutin - These can significantly reduce voriconazole levels.2. Carbamazepine and Phenobarbital - These can also decrease voriconazole effectiveness.3. Efavirenz - High doses can affect voriconazole levels.4. Ergot alkaloids - Such as ergotamine, should be avoided due to increased risk of ergotism.5. Sirolimus - Voriconazole can increase sirolimus levels, leading to toxicity.6. St. John's Wort - This herbal supplement can reduce voriconazole levels.Patients should always consult with their healthcare provider before starting or stopping any medication while on voriconazole.

Voriconazole is the drug of choice for the treatment of invasive aspergillosis, a serious fungal infection. It is also used for certain other serious fungal infections, particularly those caused by Candida species, when other treatments are not effective or appropriate.

The decision to stop taking voriconazole should be made by a healthcare provider. It is important to follow the prescribed course of treatment and not to discontinue the medication without consulting a doctor, as stopping it prematurely may lead to a recurrence of the infection. If there are concerns about side effects or the effectiveness of the medication, it is advisable to discuss these with a healthcare professional.

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