
Voriconazole Coupons & Discount Card – Guaranteed Prices from $42.60
generic Vfend
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200MG, Voriconazole (30 Tablets)
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CVS
$42.60
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$68.21
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$392.87
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CVS
$42.60
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019876
LH8BF767A7
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Voriconazole dosage forms
Dosage | Quantity | Price from | Per unit |
---|---|---|---|
50MG | 30 Tablets | $15.65 | $0.52 |
200MG | 30 Tablets | $43.59 | $1.45 |
Voriconazole Warnings
The following safety information outlines the essential warnings and precautions for the use of voriconazole (Vfend). It is important to carefully review this information and discuss any concerns with your healthcare provider.
Liver Damage: Although uncommon, voriconazole (Vfend) has been linked to liver problems. Your doctor may conduct liver function tests before and during treatment. It is advisable to limit or avoid alcohol to reduce liver damage risk. Seek immediate medical attention if you notice yellowing of the skin or eyes, changes in stool, dark urine, stomach swelling, pain, or confusion. Your doctor may advise discontinuing the medication to prevent further liver injury. Risks include pre-existing liver issues, certain blood cancers, and concurrent use of other liver-affecting medications.
Abnormal Heart Rhythm: Voriconazole (Vfend) may cause serious heart rhythm changes, such as QT prolongation. Your risk is heightened by factors like abnormal electrolyte levels, heart rhythm disorders, or concurrent use of medications affecting heart rhythm (e.g., amiodarone, ciprofloxacin). Regular heart monitoring, including ECGs, may be necessary. If you experience chest pounding, breathing difficulties, chest pain, or faintness, seek emergency medical help immediately. Risks include low potassium or magnesium levels, kidney issues, history of heart problems, and use of QT-prolonging medications.
Vision Changes: Use of voriconazole (Vfend) may lead to blurred vision, visual changes, and light sensitivity, particularly with use beyond 28 days. An eye examination is recommended if using the medication long-term or if vision changes occur. Avoid nighttime driving and wear sunglasses if bright lights cause discomfort. Consult your doctor if vision issues interfere with daily activities.
Allergic Reactions (IV Infusions): Severe allergic reactions can occur, including facial swelling and anaphylaxis. Seek immediate medical help if you experience breathing difficulty, swelling near the eyes, lips, or tongue, or dizziness after taking the medication.
Severe Skin Reactions: Rarely, voriconazole (Vfend) can cause serious skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis. If you notice skin changes like rash, blisters, or peeling, accompanied by fever and swollen lymph nodes, seek medical attention promptly.
Sun and Light Sensitivity: The medication increases skin sensitivity to sunlight and UV light, increasing the risk of sunburn. Use high-SPF sunscreen and wear protective clothing outside. Avoid prolonged sun exposure.
Pregnancy Warning: Voriconazole (Vfend) may cause developmental issues in unborn babies. If you are capable of becoming pregnant, use effective contraception during treatment. Inform your doctor immediately if you are pregnant or planning pregnancy.
Low Adrenal Hormone Levels: Some individuals report low adrenal hormone levels with azole antifungals. Symptoms include fatigue, dizziness, and nausea. Notify your doctor if these symptoms occur.
Pancreatitis: Inflammation of the pancreas has been reported. Symptoms include stomach pain, nausea, vomiting, and yellowing of the eyes or skin. Report these symptoms to your doctor for evaluation. Risks include recent chemotherapy or stem cell transplantation.
Bone and Teeth Issues: Long-term use may lead to bone pain or tooth discoloration. Report these symptoms to your doctor, as discontinuation of the medication may be needed.
Kidney Concerns: There have been reports of kidney problems, though it's unclear if voriconazole (Vfend) is the cause. Your doctor may monitor kidney function through lab tests.
Contraindications: Avoid using voriconazole (Vfend) if you are taking certain medications such as pimozide, quinidine, ivabradine, sirolimus, rifampin, carbamazepine, long-acting barbiturates, St. John's Wort, rifabutin, ergot alkaloids, naloxegol, tolvaptan, or lurasidone. Also, avoid if taking efavirenz at doses of 400 mg or higher every 24 hours, ritonavir 400 mg every 12 hours, or during the initial phases of venetoclax treatment for certain cancers due to the risk of tumor lysis syndrome.
Voriconazole Side Effects
Common side effects:
- Nausea
- Vomiting
- Headache
- Vision changes
- Rash
Less common but important to monitor:
- Fever
- Stomach pain
- Diarrhea
- Low blood potassium levels
- High blood pressure
- Cough
- Low platelet count
- Nosebleeds
Serious side effects:
- Fast or irregular heartbeat
- Severe dizziness
- Fainting
- Chills
- High liver enzymes
- Hallucinations
- Very serious liver disease
- Severe allergic reaction
Voriconazole Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- Alprazolam
- Astemizole
- Bepridil
- Cisapride
- Colchicine
- Conivaptan
- Dihydroergotamine
- Dronedarone
- Efavirenz
- Eletriptan
- Eliglustat
- Eplerenone
- Ergoloid Mesylates
- Ergonovine
- Ergotamine
- Flibanserin
- Fluconazole
- Isavuconazonium Sulfate
- Ivabradine
- Lomitapide
- Lovastatin
- Lurasidone
- Maraviroc
- Mephobarbital
- Mesoridazine
- Methylergonovine
- Methysergide
- Naloxegol
- Nelfinavir
- Nimodipine
- Phenobarbital
- Pimozide
- Piperaquine
- Posaconazole
- Primidone
- Quinidine
- Rifabutin
- Rifampin
- Ritonavir
- Saquinavir
- Simvastatin
- Sirolimus
- Sparfloxacin
- St John's Wort
- Terfenadine
- Thioridazine
- Tolvaptan
- Ubrogepant
- Venetoclax
- Voclosporin
- Ziprasidone
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Acalabrutinib
- Acenocoumarol
- Ado-Trastuzumab Emtansine
- Alfentanil
- Amiodarone
- Amisulpride
- Amitriptyline
- Amoxapine
- Anagrelide
- Apalutamide
- Apomorphine
- Aprepitant
- Aripiprazole
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Artemether
- Asenapine
- Avanafil
- Avapritinib
- Axitinib
- Azithromycin
- Bedaquiline
- Benzhydrocodone
- Boceprevir
- Bosutinib
- Brentuximab Vedotin
- Bretylium
- Brexpiprazole
- Brigatinib
- Bromocriptine
- Buprenorphine
- Buserelin
- Cabazitaxel
- Cabozantinib
- Calcifediol
- Cariprazine
- Carvedilol
- Ceritinib
- Chloramphenicol
- Chloroquine
- Chlorpromazine
- Cilostazol
- Ciprofloxacin
- Citalopram
- Clarithromycin
- Clofazimine
- Clomipramine
- Clozapine
- Cobicistat
- Cobimetinib
- Codeine
- Copanlisib
- Crizotinib
- Cyclobenzaprine
- Cyclosporine
- Dabrafenib
- Daclatasvir
- Dasabuvir
- Dasatinib
- Deflazacort
- Degarelix
- Delamanid
- Delavirdine
- Desipramine
- Deslorelin
- Deutetrabenazine
- Dexamethasone
- Dicumarol
- Dihydrocodeine
- Disopyramide
- Docetaxel
- Dofetilide
- Dolasetron
- Domperidone
- Donepezil
- Doxorubicin
- Doxorubicin Hydrochloride Liposome
- Droperidol
- Duvelisib
- Elagolix
- Elexacaftor
- Elvitegravir
- Encorafenib
- Entacapone
- Entrectinib
- Enzalutamide
- Erlotinib
- Erythromycin
- Escitalopram
- Eslicarbazepine Acetate
- Eszopiclone
- Everolimus
- Fedratinib
- Fentanyl
- Fingolimod
- Flecainide
- Fluoxetine
- Fluticasone
- Formoterol
- Fosaprepitant
- Foscarnet
- Fosphenytoin
- Fostemsavir
- Gatifloxacin
- Gemifloxacin
- Glasdegib
- Glimepiride
- Gonadorelin
- Goserelin
- Granisetron
- Halofantrine
- Haloperidol
- Histrelin
- Hydrocodone
- Hydroxychloroquine
- Hydroxyzine
- Ibrutinib
- Ibutilide
- Idelalisib
- Ifosfamide
- Iloperidone
- Imipramine
- Inotuzumab Ozogamicin
- Irinotecan
- Irinotecan Liposome
- Istradefylline
- Ivacaftor
- Ivosidenib
- Ixabepilone
- Ketoconazole
- Lansoprazole
- Lapatinib
- Larotrectinib
- Lefamulin
- Lemborexant
- Lenvatinib
- Letermovir
- Levofloxacin
- Levomilnacipran
- Lofexidine
- Lopinavir
- Lorlatinib
- Lumacaftor
- Lumateperone
- Lumefantrine
- Lurbinectedin
- Macimorelin
- Macitentan
- Manidipine
- Mefloquine
- Meperidine
- Methadone
- Metronidazole
- Midostaurin
- Mifepristone
- Mirtazapine
- Moxifloxacin
- Nafarelin
- Neratinib
- Nevirapine
- Nifedipine
- Nilotinib
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Olaparib
- Ombitasvir
- Omeprazole
- Ondansetron
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Oxycodone
- Ozanimod
- Palbociclib
- Paliperidone
- Panobinostat
- Paritaprevir
- Pasireotide
- Pazopanib
- Pemigatinib
- Pentazocine
- Pexidartinib
- Phenprocoumon
- Phenytoin
- Pimavanserin
- Pitolisant
- Ponatinib
- Ponesimod
- Pralsetinib
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quetiapine
- Quinine
- Ranolazine
- Reboxetine
- Regorafenib
- Retapamulin
- Ribociclib
- Rimegepant
- Romidepsin
- Ruxolitinib
- Salmeterol
- Selpercatinib
- Selumetinib
- Sertraline
- Sevoflurane
- Sildenafil
- Simeprevir
- Siponimod
- Sodium Phosphate
- Sodium Phosphate, Dibasic
- Sodium Phosphate, Monobasic
- Solifenacin
- Sonidegib
- Sorafenib
- Sotalol
- Sufentanil
- Sulpiride
- Sunitinib
- Suvorexant
- Tacrolimus
- Tamsulosin
- Tazemetostat
- Telaprevir
- Telavancin
- Telithromycin
- Temsirolimus
- Tetrabenazine
- Tezacaftor
- Thiotepa
- Ticagrelor
- Toremifene
- Trabectedin
- Tramadol
- Trazodone
- Triazolam
- Triclabendazole
- Trifluoperazine
- Trimipramine
- Triptorelin
- Valbenazine
- Vandetanib
- Vardenafil
- Vemurafenib
- Vilanterol
- Vilazodone
- Vinblastine
- Vincristine
- Vincristine Sulfate Liposome
- Vinflunine
- Vinorelbine
- Vorapaxar
- Voxelotor
- Warfarin
- Zanubrutinib
- Zolpidem
- Zuclopenthixol
Interactions with low risk that usually do not require a change in therapy:
- Amprenavir
- Atorvastatin
- Cerivastatin
- Desogestrel
- Dienogest
- Drospirenone
- Esomeprazole
- Estradiol
- Ethinyl Estradiol
- Ethynodiol
- Etravirine
- Fosamprenavir
- Gestodene
- Glipizide
- Glyburide
- Levonorgestrel
- Meloxicam
- Mestranol
- Midazolam
- Nomegestrol
- Norethindrone
- Norgestimate
- Norgestrel
- Tolbutamide
- Tretinoin
What is the drug voriconazole used for?
Voriconazole is an antifungal medication used to treat serious fungal infections, including invasive aspergillosis and infections caused by Candida species. It is often prescribed for patients with weakened immune systems or those who have not responded to other antifungal treatments.
What are the disadvantages of voriconazole?
Voriconazole, an antifungal medication, has several potential disadvantages and side effects. These may include:1. Visual Disturbances: Patients may experience changes in vision, such as blurred vision, color vision changes, or increased sensitivity to light.2. Liver Toxicity: There is a risk of liver damage, which may manifest as elevated liver enzymes or more severe liver dysfunction.3. Skin Reactions: Some individuals may develop skin rashes or photosensitivity, increasing the risk of sunburn.4. Neurological Effects: Possible side effects include headache, dizziness, and hallucinations.5. Drug Interactions: Voriconazole can interact with a variety of other medications, potentially altering their effects.6. QT Prolongation: It may cause changes in heart rhythm, specifically prolonging the QT interval, which can be serious.7. Renal Impairment: There is a potential risk of kidney function impairment.Patients should be monitored for these side effects, and any concerns should be discussed with a healthcare provider.
What drugs should be avoided with voriconazole?
Voriconazole can interact with several medications, and certain drugs should be avoided or used with caution. These include:1. Rifampin and Rifabutin - These can significantly reduce voriconazole levels.2. Carbamazepine and Phenobarbital - These can also decrease voriconazole effectiveness.3. Efavirenz - High doses can affect voriconazole levels.4. Ergot alkaloids - Such as ergotamine, should be avoided due to increased risk of ergotism.5. Sirolimus - Voriconazole can increase sirolimus levels, leading to toxicity.6. St. John's Wort - This herbal supplement can reduce voriconazole levels.Patients should always consult with their healthcare provider before starting or stopping any medication while on voriconazole.
What is voriconazole the drug of choice for?
Voriconazole is the drug of choice for the treatment of invasive aspergillosis, a serious fungal infection. It is also used for certain other serious fungal infections, particularly those caused by Candida species, when other treatments are not effective or appropriate.
When should I stop taking voriconazole?
The decision to stop taking voriconazole should be made by a healthcare provider. It is important to follow the prescribed course of treatment and not to discontinue the medication without consulting a doctor, as stopping it prematurely may lead to a recurrence of the infection. If there are concerns about side effects or the effectiveness of the medication, it is advisable to discuss these with a healthcare professional.