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When taking this medication, you might experience mild side effects such as drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or a dry mouth, nose, or throat. These are common and usually not a cause for concern but should be addressed if they persist or worsen. To alleviate dry mouth, consider sucking on sugarless candy or ice chips, chewing sugarless gum, drinking water, or using a saliva substitute. Additionally, this medication can make mucus in the lungs thicker, which might complicate breathing. Drinking plenty of fluids can help prevent this effect unless advised otherwise.

To minimize dizziness and lightheadedness, rise slowly from sitting or lying down positions. While many individuals do not experience serious side effects, it is important to be aware of them. Contact your healthcare provider immediately if you experience mental or mood changes, such as confusion or hallucinations, ringing in the ears, tremors, trouble urinating, weakness, easy bruising or bleeding, irregular heartbeat, or seizures. Although rare, severe allergic reactions can occur. Seek immediate medical attention if you notice symptoms like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. Always stay vigilant and consult your healthcare provider if you encounter any unusual symptoms not listed here.

Combining this medication with certain MAO inhibitors can lead to a severe, potentially life-threatening interaction. Do not take isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while using this medication. Additionally, most MAO inhibitors should be avoided for two weeks before and after your treatment with this drug. Consult your doctor for guidance on when to begin or discontinue this medication.

This drug may also interact with products like skin-applied antihistamines (such as diphenhydramine cream, ointment, spray) and rolapitant. Inform your doctor or pharmacist if you are using other products that induce drowsiness, including opioid pain relievers or cough suppressants (such as codeine, hydrocodone), alcohol, marijuana, medications for sleep or anxiety (such as Alprazolam, Lorazepam, Zolpidem), muscle relaxants (such as Carisoprodol, Cyclobenzaprine), or additional antihistamines (such as Cetirizine, diphenhydramine).

Be sure to check the labels of all your medications, including those for allergies or cold symptoms, as they may contain ingredients that cause drowsiness. Discuss safe usage of these products with your pharmacist.

Lastly, this medication might affect certain medical or laboratory tests, including brain scans for Parkinson's disease, urine drug screenings, and allergy skin tests, potentially leading to inaccurate results. Ensure that all your healthcare providers and lab personnel are aware that you are taking this medication.