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When taking this medication, it's important to be aware of potential interactions and precautions. Here are key points to consider:

• Drug Interactions: Some topical antihistamines, like diphenhydramine creams, ointments, or sprays, may interact with this medication. Additionally, inform your healthcare provider if you are using other substances that can cause drowsiness, such as:

  • Opioid pain or cough medications (e.g., codeine, hydrocodone).
  • Alcohol or marijuana (cannabis).
  • Medications for sleep or anxiety (e.g., alprazolam, lorazepam, zolpidem).
  • Muscle relaxants (e.g., carisoprodol, cyclobenzaprine).
  • Other antihistamines (e.g., cetirizine, chlorpheniramine).

• Medication Labels: Review all your medications, including those for allergies or coughs and colds, as they may contain ingredients that induce drowsiness. Consult your pharmacist to ensure safe use of these products.

• Laboratory Tests: This drug may interfere with certain laboratory tests, such as allergy skin tests, potentially leading to inaccurate results. It is crucial to inform lab personnel and all your healthcare providers that you are using this medication.

Adhering to these guidelines will help you manage your medication safely and effectively.

Common side effects:

• Drowsiness
• Dizziness
• Constipation
• Stomach upset
• Blurred vision
• Dryness in the mouth, nose, or throat

Less common but important to monitor:

• Mental or mood changes (such as confusion or restlessness)
• Trouble urinating
• Fast or irregular heartbeat

Serious side effects:

• Seizures
• Allergic reactions (rash, itching, swelling of the face, tongue, or throat, severe dizziness, difficulty breathing)

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• topical antihistamines (such as diphenhydramine cream, ointment, spray)
• opioid pain or cough relievers (such as codeine, hydrocodone)
• alcohol
• marijuana (cannabis)
• medications for sleep or anxiety (such as Alprazolam, Lorazepam, Zolpidem)
• muscle relaxants (such as Carisoprodol, Cyclobenzaprine)
• other antihistamines (such as Cetirizine, chlorpheniramine)