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The following safety information outlines potential risks and necessary precautions associated with the use of hyoscyamine. It is important to review these carefully and consult with your healthcare provider if you have any questions or concerns.

• Dizziness and Drowsiness: Hyoscyamine may induce sleepiness, dizziness, or blurred vision. Avoid driving or engaging in tasks that require full attention until you understand how this medication affects you.

• Mood and Cognitive Changes: This medication can affect mood, thoughts, or cognitive abilities, potentially causing confusion, memory issues, or disorientation. Symptoms might include agitation, hallucinations, or euphoria, and in severe cases, may lead to a coma. These effects usually resolve within 12 to 48 hours after discontinuing the medication. Notify your provider immediately if you experience any mood or cognitive alterations. Higher risk is observed in individuals aged 65 or older and those with mental health conditions.

• Increased Heart Rate: Patients with heart conditions such as heart failure, previous heart attacks, or hypertension should inform their healthcare provider, as hyoscyamine might elevate heart rate, potentially aggravating these conditions. Report any heart rate changes or symptoms like a racing or pounding heart to your provider. Risks increase with pre-existing heart issues or high blood pressure.

• Autonomic Nervous System Changes: Hyoscyamine can influence involuntary bodily functions. It may slow gut muscles, leading to constipation, reduce saliva or sweat production resulting in dry mouth and thirst, and increase susceptibility to heat stroke. It may also affect heartbeat and vision. Inform your provider about any changes in bodily functions. Avoid taking hyoscyamine if you have a fever without consulting your provider first. The elderly are at higher risk.

• Urination Issues: Those with prostate conditions should use hyoscyamine cautiously as it may exacerbate difficulties in urination.

• Gastrointestinal Precautions: Inform your provider if you have had a colostomy or similar procedures before using hyoscyamine for diarrhea. Diarrhea might indicate a gut blockage, and taking hyoscyamine under such conditions could be harmful.

Contraindications: Hyoscyamine should not be used in the presence of certain conditions due to serious health risk potential. Consult your healthcare provider if you have:

• Glaucoma
• Urinary tract blockage
• Stomach or intestinal blockage
• Long-term constipation
• Unstable heart or bleeding issues
• Severe ulcerative colitis with toxic megacolon
• Myasthenia gravis

This information is crucial for ensuring safe medication use and avoiding adverse effects. Always discuss any concerns with your healthcare provider.

When taking this medication, it's common to experience mild side effects such as dizziness, drowsiness, blurred vision, dry mouth, headache, trouble sleeping, constipation, and flushing. These are typically not serious and should ease with time. To mitigate dry mouth, consider sucking on sugarless candy, chewing gum, or drinking water. Additionally, some individuals may experience dry skin and a decreased ability to sweat, which can usually be managed effectively.

Although less common, some users may experience trouble urinating, dry eyes, and a slightly elevated heart rate. These effects are generally mild but should be monitored. If you notice any persistent or worsening symptoms, consulting a healthcare provider is advisable.

In rare cases, more serious side effects can occur and should be addressed immediately. These include severe mood changes, confusion, or hallucinations, as well as a fast or irregular heartbeat. If you experience symptoms like chest discomfort, shortness of breath, or severe dizziness, seek medical attention promptly.

An allergic reaction to this medication is rare but serious. Symptoms can include rash, itching, swelling, severe dizziness, or trouble breathing. If these occur, immediate medical intervention is necessary. Always inform your healthcare provider if you notice any side effects not listed, as this helps ensure your safety and wellbeing.

When taking this medication, it's important to be aware of possible interactions with other drugs. Some medications that may interact include certain antifungal drugs like Ketoconazole and Itraconazole, bisphosphonates such as Alendronate and Risedronate, corticosteroids like Prednisone, slow-dissolving Digoxin tablets, potassium supplements, and pramlintide. Additionally, drugs that induce drowsiness, such as opioid pain relievers (e.g., codeine, hydrocodone), alcohol, marijuana, sleep or anxiety medications (e.g., Alprazolam, Lorazepam, Zolpidem), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), and antihistamines (e.g., Cetirizine, diphenhydramine), can also interact with this medication.

Certain medications should not be combined with this drug, such as ambenonium, bepridil, bromopride, cisapride, dronedarone, and Pimozide, due to potential adverse effects. In some cases, the combination of medications might be necessary, but your doctor may adjust the dosage or frequency. This includes medicines like alprazolam, codeine, digoxin, hydrocodone, lorazepam, and Potassium Chloride, among others.

Always inform your healthcare provider about any medications, vitamins, or supplements you are taking. Also, check with your pharmacist to ensure all your medications, including over-the-counter products, are safe to use together. This medication may also interfere with certain lab tests, leading to inaccurate results, so make sure your healthcare team is informed of all the medications you are using.