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This medication comes with several important safety warnings and precautions. Please read through this information carefully and consult your healthcare provider if you have any questions or concerns.

• Liver Damage: Erythromycin can potentially cause severe or life-threatening liver damage, especially if you have a history of liver problems. Be alert for symptoms such as unexplained stomach pain, nausea, vomiting, dark urine, pale stools, or yellowing of the skin or eyes, and contact your healthcare provider immediately if these occur. Regular blood tests are recommended to monitor liver function.

• Heart Rhythm Changes (QT Prolongation): In rare cases, erythromycin may cause a serious heart rhythm problem known as QT prolongation, which could be fatal. This risk is heightened in individuals with certain heart conditions or those over 65. Avoid taking erythromycin with other medications that also cause QT prolongation. Inform your healthcare provider about any heart conditions and provide a comprehensive list of all medications and supplements you are taking.

• Syphilis in Infants: Erythromycin may not fully prevent syphilis transmission from mother to baby during pregnancy, as it might not reach the baby effectively. If you were treated with erythromycin for syphilis during pregnancy, inform your healthcare provider; your baby will require antibiotics after birth.

• Severe Diarrhea (C. difficile): Erythromycin may increase the risk of Clostridioides difficile-associated diarrhea (CDAD), a potentially life-threatening condition. Stop taking erythromycin and seek medical attention if you experience bloody or watery stools. This risk is higher in individuals over 65, those with weakened immune systems, recent hospital stays, or prolonged antibiotic use.

• Drug Interactions: Erythromycin interacts with many medications, some of which can be dangerous. Consult your healthcare provider about all medications you are taking to avoid potential heart rhythm complications.

• Myasthenia Gravis: Erythromycin can exacerbate symptoms of myasthenia gravis, such as muscle weakness and breathing difficulties. Discuss any concerns with your healthcare provider if you have this condition.

• Intestinal Blockage in Infants: Erythromycin can cause a blockage between the stomach and small intestine in infants, especially with prolonged use. It is generally not recommended for infants unless necessary for life-threatening conditions. Watch for symptoms like vomiting or fussiness while eating and contact your child's healthcare provider immediately if they occur.

Contraindications: This medication should not be used if you are taking terfenadine, astemizole, pimozide, cisapride, ergotamine, dihydroergotamine, lovastatin, or simvastatin (Zocor). Consult your healthcare provider if you are on any of these medications.

When taking Ery-Tab (erythromycin), it's important to be aware of potential interactions with other medications, certain health conditions, and specific foods. These interactions can affect how Ery-Tab works or increase the risk of side effects.

Drug Interactions:

• Heart Rhythm Medications: Combining Ery-Tab with drugs that prolong the QT interval, such as certain antiarrhythmics, can increase the risk of serious heart rhythm problems.

• Statins: Ery-Tab may raise the levels of statins like Simvastatin and Lovastatin in your body, potentially leading to muscle-related side effects.

• Migraine Medications: Using Ery-Tab with ergotamine or Dihydroergotamine can enhance their effects, increasing the risk of adverse reactions.

• Blood Thinners: Ery-Tab can interact with anticoagulants like Warfarin, affecting blood clotting and increasing bleeding risk.

• Immunosuppressants: Medications such as Cyclosporine may have increased levels when taken with Ery-Tab, heightening the risk of side effects.

Disease Interactions:

• Liver Disease: Ery-Tab is processed by the liver, so individuals with liver conditions should use it cautiously to avoid potential complications.

• Myasthenia Gravis: This medication may worsen symptoms of myasthenia gravis, a condition causing muscle weakness.

• Heart Conditions: Ery-Tab can prolong the QT interval, which may lead to serious heart rhythm issues, especially in those with existing heart problems.

Food Interactions:

• Grapefruit Products: Consuming grapefruit or grapefruit juice can increase Ery-Tab levels in your body, potentially leading to more side effects. It's advisable to avoid grapefruit products while taking this medication.

• Food Intake: Food can decrease the absorption of Ery-Tab. To ensure optimal effectiveness, take it on an empty stomach, at least 30 minutes before or 2 hours after a meal.

Always inform your healthcare provider about all medications, supplements, and health conditions before starting Ery-Tab. This will help manage potential interactions and ensure the medication is safe and effective for you.