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Diarrhea may occur. If this effect lasts or gets worse, tell your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: symptoms of high magnesium levels (such as muscle weakness, slow/irregular heartbeat, slow/shallow breathing, mental/mood changes such as confusion), symptoms of dehydration (such as decreased urination, dizziness, extreme thirst, very dry mouth), stomach/abdominal pain, bloody stools, rectal bleeding. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Some products that may interact with this drug include: raltegravir, sodium polystyrene sulfonate. Magnesium hydroxide can decrease the absorption of other drugs such as dasatinib, atazanavir, gabapentin, digoxin, mycophenolate, phosphate supplements (such as potassium phosphate), tetracycline antibiotics (such as doxycycline, minocycline), certain azole antifungals (ketoconazole, itraconazole), and quinolone antibiotics (such as ciprofloxacin, levofloxacin). Separate your doses of these medications as far as possible from your doses of magnesium hydroxide. Ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.