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Lubiprostone

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generic Amitiza

This medication is used to treat certain types of constipation (chronic idiopathic constipation, irritable bowel syndrome with constipation). Chronic idiopathic constipation has an unknown cause and is not due to diet, other diseases, or drugs. Lubiprostone is also used to treat constipation caused by opioid medications in people with ongoing pain due to medical conditions other than cancer. This medication may improve symptoms such as bloating and abdominal discomfort, improve stool texture, lessen the need to strain, and decrease the feeling of not completely relieving oneself. Lubiprostone belongs to a class of drugs known as chloride channel activators. It works by increasing the amount of fluid within your intestines, making the passage of stool easier.
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24MCG, Lubiprostone (30 Capsules)

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CVS

$25.29

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$27.25

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$39.72

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$43.57

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$50.10

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Lubiprostone Side Effects

Nausea, diarrhea, gas, vomiting, dry mouth, runny nose, cough, fever, headache, joint/back pain, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: swelling of arms/legs, mental/mood changes. This medication may cause low blood pressure and possibly fainting. Diarrhea and vomiting may increase the risk of these side effects. Stop taking this medication and tell your doctor right away if any of these serious side effects occur: fainting, dizziness, severe diarrhea/vomiting. Lubiprostone may rarely cause trouble breathing and chest tightness within 30 to 60 minutes after the first dose. This reaction is usually not serious and generally goes away within 3 hours. It may happen again with other doses. However, you may not be able to tell this reaction apart from a rare, severe reaction that also causes trouble breathing and/or chest pain. Get medical help right away if you develop any trouble breathing or chest tightness/discomfort/pain. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Lubiprostone FAQs
What are the disadvantages of lubiprostone?

Lubiprostone may have several disadvantages or side effects. Common side effects include nausea, diarrhea, headache, abdominal pain, and flatulence. Some patients may experience difficulty breathing or chest tightness shortly after taking the medication, although this is typically transient. It is also important to note that lubiprostone is not recommended for individuals with a history of bowel obstruction. As with any medication, it is essential to discuss potential risks and benefits with a healthcare provider.

Lubiprostone is not a stimulant laxative. It is a type of medication known as a chloride channel activator, which works by increasing fluid secretion in the intestines to help ease the passage of stool.

Amitiza and Linzess are not the same medication, although both are used to treat certain types of constipation. Amitiza (lubiprostone) is typically used for chronic idiopathic constipation and irritable bowel syndrome with constipation in adults. Linzess (linaclotide) is used for similar conditions but works through a different mechanism. It is important for patients to follow their healthcare provider's recommendations regarding which medication is appropriate for their specific condition.

Lubiprostone is generally well-tolerated, but long-term effects can include nausea, diarrhea, and abdominal pain. Some patients may experience headaches or dizziness. It is important for patients to discuss any persistent or concerning symptoms with their healthcare provider to ensure appropriate management. Regular follow-up is recommended to monitor the effectiveness and any potential side effects of the medication.

Lubiprostone should not be taken by individuals who have a known hypersensitivity to the drug or any of its components. It is also contraindicated in patients with mechanical gastrointestinal obstruction. Additionally, it should be used with caution in individuals with severe diarrhea. Pregnant women should consult their healthcare provider before using lubiprostone, as its safety during pregnancy has not been fully established.

If someone is considering alternatives to lubiprostone, they should consult with their healthcare provider to determine the most appropriate option based on their specific condition and medical history. Some potential alternatives for treating chronic idiopathic constipation or irritable bowel syndrome with constipation may include:1. Linaclotide (Linzess): Another medication that can help increase bowel movements.2. Plecanatide (Trulance): Used for chronic idiopathic constipation and IBS-C.3. Polyethylene glycol (MiraLAX): An over-the-counter osmotic laxative.4. Lactulose: A prescription osmotic laxative.5. Dietary changes: Increasing fiber intake and staying hydrated.6. Lifestyle modifications: Regular exercise and establishing a routine for bowel movements.It's important to discuss these options with a healthcare provider to ensure safety and effectiveness.

Lubiprostone is not known to have a direct effect on kidney function. It primarily acts on the gastrointestinal tract to increase fluid secretion and improve bowel movements. However, as with any medication, it is important for patients with kidney issues to consult their healthcare provider before starting lubiprostone to ensure it is safe for their specific condition.

Amitiza is not a stimulant laxative. It is a type of medication known as a chloride channel activator, which works by increasing fluid secretion in the intestines to help ease the passage of stool.

The effectiveness of lubiprostone versus Miralax (polyethylene glycol 3350) depends on the individual's specific condition and response to treatment. Lubiprostone is typically prescribed for chronic idiopathic constipation and irritable bowel syndrome with constipation, while Miralax is an over-the-counter osmotic laxative used for occasional constipation. A healthcare provider can help determine which medication is more appropriate based on the patient's symptoms and medical history.

Lubiprostone has been shown to be effective in treating chronic idiopathic constipation and irritable bowel syndrome with constipation. Clinical trials have demonstrated that approximately 57% to 63% of patients experience significant improvement in symptoms. However, individual responses can vary, and it is important for patients to discuss their specific situation with their healthcare provider.

The effectiveness of Linzess (linaclotide) versus Amitiza (lubiprostone) can vary depending on the individual and the specific condition being treated. Both medications are used to treat chronic constipation and irritable bowel syndrome with constipation (IBS-C), but they work in different ways. Linzess is often prescribed for its ability to increase fluid secretion in the intestines and speed up the movement of stool through the bowel. Amitiza, on the other hand, works by increasing fluid in the intestines to help with stool passage.The choice between Linzess and Amitiza should be based on a healthcare provider's assessment of the patient's specific symptoms, medical history, and response to previous treatments. It is important for patients to discuss with their healthcare provider which medication might be more suitable for their condition.

A healthcare provider may consider alternatives to Linzess (linaclotide) based on the patient's specific condition and response to treatment. Possible substitutes could include other medications for irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation (CIC), such as:- Lubiprostone (Amitiza): Another medication that increases fluid secretion in the intestines to help with bowel movements.- Plecanatide (Trulance): Similar to Linzess, it works by increasing intestinal fluid and accelerating transit.- Over-the-counter options: Such as fiber supplements, stool softeners, or osmotic laxatives like polyethylene glycol (MiraLAX).It is important for the patient to consult with their healthcare provider to determine the most appropriate alternative based on their medical history and symptoms.

Amitiza (lubiprostone) and Linzess (linaclotide) are both medications used to treat certain types of constipation. While there is no direct contraindication to taking them together, it is important for a patient to consult with their healthcare provider before doing so. The healthcare provider can assess the patient's specific condition, potential benefits, and risks, and determine the most appropriate treatment plan.