Nucala

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Nucala (mepolizumab) is an injection used as an add-on treatment to manage severe asthma that isn't controlled by other medications. It is also used to treat certain inflammatory conditions like chronic rhinosinusitis with nasal polyps, eosinophilic granulomatosis with polyangiitis, and hypereosinophilic syndrome. Nucala works by targeting interleukin-5 (IL-5), a protein responsible for the production of eosinophils, a type of white blood cell that contributes to inflammation. By reducing eosinophil levels, Nucala helps lower inflammation, making breathing easier and alleviating symptoms like pain and swelling. The medication comes in a prefilled autoinjector or syringe for convenience, allowing for administration by a healthcare provider or at home with proper training. It is important to use Nucala regularly as it does not provide immediate relief and should not be used during sudden asthma attacks. For acute asthma symptoms, continue using your prescribed quick-relief inhaler. Potential side effects include headache, reactions at the injection site, and pain in the throat, back, or joints. Always consult with your healthcare provider before starting any new medication.
Our Nucala coupons are free to use. You can print the coupon, email it to yourself, or receive the Nucala coupon via text message. To get your free discount, show the pharmacist your Nucala savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Nucala prices will update based on your prescription needs. Above our Nucala coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Nucala savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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100MG, Nucala (30 Solution Reconstituteds)

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Rite Aid

$105532.65

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$109984.19

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Nucala dosage forms

The average cost for 30 Solution Reconstituteds of Nucala at 100MG is $106814.97 with a free coupon. This is 27.94% off the average retail price of $382348.17
DosageQuantityPrice fromPer unit
100MG30 Solution Reconstituteds$106814.97$3560.5

Nucala Warnings

This information outlines critical safety considerations for the use of Nucala (mepolizumab). It is important to read and understand these warnings, and consult your healthcare provider if you have any questions or concerns.

  • Allergic Reactions: Nucala (mepolizumab) has the potential to cause severe allergic reactions, such as hives, wheezing, breathing difficulties, or swelling of the face, mouth, tongue, or throat (anaphylaxis). These reactions may occur within hours or even days after administration. Therefore, initial treatments should be conducted under medical supervision, with close monitoring following each dose to ensure no serious reactions occur. If you experience any symptoms of an allergic reaction outside a healthcare facility, seek emergency medical help immediately by calling 911.

  • Not for Acute Asthma Attacks: Nucala (mepolizumab) is designed to be an adjunctive maintenance therapy for asthma, meant to be used alongside other asthma medications for long-term management. It is not suitable for treating acute asthma attacks; for immediate relief during an asthma attack, use a rescue inhaler such as albuterol.

  • Corticosteroid Use: If you are on oral or inhaled corticosteroids, do not abruptly discontinue them without consulting your healthcare provider, even if you notice improvements with Nucala (mepolizumab). Stopping corticosteroids suddenly can lead to withdrawal symptoms such as dizziness, extreme fatigue, body aches, and vomiting. Your healthcare provider will guide you on how to safely reduce or discontinue corticosteroid use if necessary.

  • Infection Risk: There is a rare risk of developing herpes zoster (shingles) while on Nucala (mepolizumab). Discuss with your healthcare provider whether you should receive the herpes zoster vaccine (Shingrix) before starting this medication.

Nucala Side Effects

When using this medication, there are a few common side effects that may occur. These include headaches and reactions at the injection site, such as pain, redness, swelling, itching, or burning. These are generally mild and affect a small percentage of users. Fatigue and back pain are also reported but are usually manageable. If these effects persist or worsen, consulting a healthcare provider is advisable to ensure your comfort and safety.

In addition to the common side effects, some individuals may experience throat or joint pain. While these are less common, they should be monitored. If the symptoms become bothersome or more severe, it's important to contact a healthcare provider for guidance.

Although serious side effects are rare, it is crucial to be aware of them. A severe allergic reaction, identified by symptoms such as a rash, swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing, requires immediate medical attention. Muscle aches, pain, or spasms should also be promptly reported to a healthcare professional. Remember, while these severe reactions are unlikely, being informed helps you respond effectively should they occur.

Nucala FAQs
What exactly does NUCALA do?

NUCALA (mepolizumab) is a monoclonal antibody that targets and inhibits interleukin-5 (IL-5), a protein involved in the growth and survival of eosinophils, which are a type of white blood cell. By reducing the levels of eosinophils, NUCALA helps manage conditions characterized by high eosinophil counts, such as severe eosinophilic asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). It is used as an add-on maintenance treatment to help control symptoms and reduce the frequency of exacerbations in these conditions.

The cost of a NUCALA (mepolizumab) injection can vary depending on factors such as location, insurance coverage, and the pharmacy or healthcare provider. On average, the price without insurance can range from $3,000 to $5,000 per injection. Patients are advised to check with their insurance provider for coverage details and potential out-of-pocket costs. Additionally, there may be patient assistance programs available to help reduce the cost.

Weight gain is not commonly reported as a side effect of NUCALA (mepolizumab). However, individual reactions to medications can vary. If there are concerns about weight changes while taking NUCALA, it is advisable to consult with a healthcare provider for personalized advice and evaluation.

NUCALA (mepolizumab) and Dupixent (dupilumab) are both biologic medications used to treat different conditions, although there is some overlap. NUCALA is primarily used for severe eosinophilic asthma and other eosinophilic conditions, working by targeting interleukin-5 (IL-5) to reduce eosinophil levels. Dupixent, on the other hand, is used for moderate-to-severe atopic dermatitis, asthma, and chronic rhinosinusitis with nasal polyposis. It targets interleukin-4 (IL-4) and interleukin-13 (IL-13) pathways to reduce inflammation. The choice between them depends on the specific condition being treated and the patient's medical history.

The effectiveness of Nucala can be assessed by monitoring the patient's symptoms and overall health. If Nucala is working, the patient may experience a reduction in the frequency and severity of asthma attacks, improved lung function, and a decrease in the need for oral corticosteroids. Additionally, the patient might notice an improvement in their ability to perform daily activities without experiencing asthma-related symptoms. Regular follow-up appointments with a healthcare provider are essential to evaluate the treatment's effectiveness and make any necessary adjustments.

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