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Serevent Diskus (salmeterol) is a medication used in the treatment of asthma and other related respiratory conditions. However, it is important to be aware of certain safety precautions and potential risks associated with its use. Please review the following information carefully and discuss any concerns with your healthcare provider.

• Asthma Treatment: Salmeterol should not be used as the sole medication for asthma. It must be combined with an inhaled corticosteroid. Using salmeterol alone increases the risk of severe asthma-related events, including hospitalization or death. This warning does not apply to individuals with COPD or exercise-induced bronchospasm without persistent asthma.

• Bronchospasm Warning: Some inhaled medications, including salmeterol, can induce bronchospasm, a condition where the airways tighten, leading to breathing difficulties, wheezing, and chest discomfort. Use a rescue inhaler immediately if you experience these symptoms after using salmeterol and seek medical attention.

• Allergic Reactions: There is a risk of severe allergic reactions to salmeterol, such as facial swelling, anaphylaxis, or shock. If you experience hives, rash, swelling of the lips or tongue, or difficulty breathing, seek emergency medical care. Note that individuals with a milk protein allergy should be particularly cautious.

• Immediate Relief: Salmeterol is not intended for rapid relief of sudden breathing problems. For immediate treatment, use a rescue inhaler like albuterol.

• Heart Health: Salmeterol may elevate blood pressure and heart rate or cause changes in heart rhythm. These effects are uncommon at recommended doses, but monitor your heart rate and blood pressure if you have heart conditions. Avoid using salmeterol more frequently than prescribed, and consult your healthcare team if you experience symptoms like dizziness, rapid heartbeat, or fatigue.

• Potassium Levels: Beta agonists, such as salmeterol, might lower potassium levels in the blood, although this was not observed in clinical trials. Be aware of symptoms like tiredness and muscle cramps, especially if using higher doses.

• Contraindications: Do not use salmeterol without an inhaled corticosteroid if you have asthma. Avoid using it during an acute asthma attack or COPD flare-up. Individuals with severe milk protein allergies should not use this medication.

If you suspect an overdose of salmeterol, seek immediate medical assistance. Always follow your healthcare provider’s instructions and report any unusual symptoms or concerns during treatment.

This medication may lead to a variety of side effects, some of which are common and others more severe. Common side effects include headache, muscle pain, stuffy nose, sore throat, and respiratory infections. These effects are generally mild, but if they persist or worsen, it is advisable to consult a healthcare provider. Other side effects that might occur are runny nose, cough, rash, itching, nausea or vomiting, and dizziness. These are typically not serious but should be discussed with a healthcare provider if they become problematic.

In more serious cases, this medication can cause severe side effects that require immediate medical attention. Such severe reactions include a sudden narrowing of the airways, also known as bronchospasm, which can result in throat swelling, difficulty breathing, wheezing, chest pain, and coughing. Serious heart problems may also occur, presenting symptoms like an irregular heartbeat, severe dizziness, fainting, seizures, or chest pain. Additionally, a severe allergic reaction, though rare, can happen and is characterized by hives, swelling of the face, lips, or tongue, and difficulty breathing.

It is important to monitor your condition and seek immediate medical help if any of these serious side effects occur. Regularly check your blood pressure, as this medication may elevate it. Remember that while many people do not experience serious side effects, being aware and vigilant about any changes can help ensure your safety while using this medication.