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The safety and warning information for Symbicort (budesonide / formoterol) is critical for users to understand the potential risks and precautions associated with its use. Below are the key points to consider:

• Exacerbation of Asthma or COPD: In rare cases, Symbicort can lead to a condition known as paradoxical bronchospasm, which may worsen asthma or COPD symptoms. If you experience increased wheezing, shortness of breath, or coughing after using this medication, discontinue use immediately and contact your healthcare provider.

• Overdose Risks: Taking Symbicort more frequently, in higher doses than prescribed, or in combination with other long-acting beta-agonists (LABAs) like Striverdi Respimat can lead to overdose. Symptoms include chest pain, rapid heartbeat, dizziness, headache, dry mouth, muscle cramps, nausea, or difficulty sleeping. Seek medical help immediately if overdose is suspected.

• Oral Thrush: Fungal infections such as oral thrush can occur, especially if you do not rinse your mouth after using Symbicort. Signs include white patches, redness, or soreness in the mouth. Consult your provider if symptoms appear, as antifungal treatment may be necessary.

• Increased Infection Risk: Symbicort can make individuals more susceptible to infections like tuberculosis, chickenpox, and measles. Avoid use if you have an active or recurrent infection without consulting your provider. Report any symptoms of infection, such as fever or sore throat, to your healthcare provider promptly.

• Transitioning from Oral to Inhaled Steroids: Transitioning may lead to withdrawal symptoms. Watch for signs like nausea, fatigue, or joint pain. Do not alter steroid forms without professional guidance.

• Adrenal Suppression: Long-term use can result in decreased adrenal function, leading to dependence on steroids. Symptoms can include fever, joint pain, and fatigue in adults, and growth issues in children. Adhere to prescribed doses and consult your provider before stopping the medication.

• Cardiovascular Concerns: Excessive use can provoke serious issues such as seizures and heart problems. Avoid using Symbicort with other LABAs and adhere to prescribed usage.

• Bone and Growth Health: Prolonged use may lead to bone loss or growth issues. Regular bone density assessments are advised for those with a history of osteoporosis or fractures.

• Eye Health: Long-term use can increase eye pressure and exacerbate glaucoma or cataracts. Report any visual changes to your provider.

• Allergic Reactions: If you have a history of allergies to budesonide, avoid this medication. Seek immediate medical attention for symptoms such as wheezing, dizziness, or swelling.

• Electrolyte Imbalance: Symbicort may cause temporary low potassium levels, affecting heart rhythm. Notify your provider if you experience muscle weakness or abnormal heartbeats.

Contraindications: This medication should not be used during asthma attacks or severe episodes of asthma or COPD. Always consult your healthcare provider if you are unsure about the suitability of this medication for your condition.

When taking this medication, some individuals may experience mild side effects such as headache, sore throat, or an upset stomach. These are generally not serious, but if they persist or worsen, it's important to consult a healthcare provider. Common ailments like a common cold, upper respiratory tract infections, and a stuffy nose might also occur.

In rare instances, more serious side effects may arise, requiring prompt medical attention. These include sudden worsening of breathing problems or asthma, severe dizziness, chest pain, irregular heartbeat, fainting, or seizures. Additionally, watch for symptoms such as white patches in the mouth, signs of infection like a persistent sore throat or fever, mental changes, trouble sleeping, vision issues, increased thirst or urination, muscle cramps, and tremors.

Severe allergic reactions are infrequent but can be serious. Symptoms to look out for include rash, itching, swelling (particularly of the face, tongue, or throat), and sudden breathing difficulties. If you experience these, seek medical help immediately.

It's important to monitor your blood pressure during treatment, as this medication can cause an increase. Regular monitoring can help manage any potential issues. Although this medication is beneficial for many, always stay alert to any unusual side effects and discuss them with your healthcare provider.

Symbicort (budesonide/formoterol) may interact with several other medications. It is crucial to inform your healthcare provider about all medicines and supplements you are taking, including prescription, over-the-counter, vitamins, and herbal products.

Some medications should not be used with Symbicort due to potential interactions. These include Desmopressin, Bepridil, Cisapride, Dronedarone, Mesoridazine, Pimozide, Piperaquine, Saquinavir, Sparfloxacin, Terfenadine, Thioridazine, and Ziprasidone. If you are currently using any of these, your doctor might suggest an alternative treatment or adjust your medications.

In certain situations, using Symbicort with other drugs like Mifepristone, Acebutolol, Aceclofenac, Amiodarone, Aripiprazole, Atazanavir, Azithromycin, and other listed medications is generally not recommended. However, if both drugs are necessary for your treatment, your healthcare provider may modify the dose or frequency of use to minimize risks.

Lastly, combining Symbicort with medicines such as Auranofin, Erythromycin, and Ketoconazole might increase the risk of side effects. Nonetheless, your doctor might decide that the combined treatment is essential, in which case they will closely monitor and adjust your treatment as needed. Always follow your healthcare provider's guidance on medication use to ensure safe and effective treatment.