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The following information outlines essential safety warnings and potential risks associated with the use of Admelog (insulin lispro). It is crucial to understand these details and discuss any concerns with your healthcare provider.

• Infection Risk from Shared Injection Supplies: Do not share Admelog pens, syringes, needles, or cartridges with others, as this can spread serious infections.

• Blood Sugar Variability: Adjustments in your insulin routine, such as changing the site of injection or switching insulin brands, can lead to fluctuating blood sugar levels. Injecting into areas with lipodystrophy may also result in high blood sugar. Factors like diet changes, alcohol consumption, other diabetes medications, and liver or kidney issues can increase this risk.

• Hypoglycemia (Low Blood Sugar): Using Admelog alone or with other blood sugar-lowering medications can cause hypoglycemia, a potentially life-threatening condition. Risks include dietary changes, alcohol use, improper insulin use, and pre-existing liver or kidney conditions.

• Allergic Reactions: Though rare, some individuals may experience an allergic response to Admelog. Seek immediate medical attention if you encounter breathing difficulties, or swelling of the face, lips, tongue, or throat, or develop a rash.

• Hypokalemia (Low Potassium Levels): Admelog may reduce potassium levels, which can be hazardous, especially if you are on potassium-lowering medications such as certain diuretics. Symptoms include weakness, muscle cramps, nausea, and irregular heartbeats. Regular potassium level monitoring by your prescriber is recommended.

• Fluid Retention and Heart Failure Risk: Using Admelog with glitazones (thiazolidinediones) like pioglitazone can cause fluid retention, exacerbating or leading to heart failure. Notify your healthcare provider of any sudden weight gain or heart failure symptoms such as breathlessness, fatigue, or headaches.

• High Blood Sugar and Ketoacidosis with Insulin Pumps: For those using insulin pumps, ensure correct usage and functionality to avoid extreme blood sugar spikes or ketoacidosis. Contact your healthcare provider promptly if pump issues arise and consider alternative injection methods if needed.

Contraindications: Do not use Admelog if you have symptoms of hypoglycemia. Always consult your healthcare provider before use if you have any contraindicated conditions.

When using this medication, some common side effects might include injection site reactions like pain, redness, or irritation, as well as weight gain. These effects are generally mild, but if they persist or worsen, it's important to consult a healthcare provider. Low blood sugar, or hypoglycemia, is another potential side effect and may manifest as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling in the hands or feet. To manage low blood sugar, it's helpful to carry glucose tablets or gel, or consume a quick source of sugar such as candy or fruit juice. Regular meals and avoiding skipping meals can help prevent this condition.

More serious, though rare, side effects require immediate medical attention. These include signs of severely low blood sugar, such as confusion, irritability, or faintness, and symptoms of very low potassium levels, like muscle cramps, weakness, or irregular heartbeat. Ketoacidosis, characterized by nausea, vomiting, stomach pain, and fruity breath, is another severe side effect that demands urgent care. Allergic reactions, though uncommon, can also occur, leading to rash, itching, swelling, severe dizziness, or trouble breathing.

Additionally, some users might experience other side effects like rash, itchiness, lumps or thickened skin at the injection site, swelling, common cold symptoms, or upper respiratory tract infections. While these are generally not severe, discussing them with a healthcare provider is advised if they become troublesome. Always be vigilant for any unusual symptoms and seek medical advice as needed.