Glipizide-metformin Hcl Coupons & Discount Card – Guaranteed Prices from $34.20
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2.5-250MG, Glipizide-metformin Hcl (180 Tablets)
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$34.20
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$47.15
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$56.37
COUPON PRICEGlipizide-metformin Hcl savings card
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$34.20
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More prescriptions for diabetes type 2
More prescriptions for diabetes type 2
Glipizide-metformin Hcl dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 5-500MG | 180 Tablets | $34.2 | $0.19 |
| 2.5-500MG | 180 Tablets | $34.2 | $0.19 |
| 2.5-250MG | 180 Tablets | $34.2 | $0.19 |
Glipizide-metformin Hcl Warnings
This medication, combining glipizide and metformin, has specific safety information and warnings that must be carefully considered to minimize potential risks. Below are critical details regarding its use:
Lactic Acidosis Risk: Rarely, metformin can accumulate in the body, leading to a potentially fatal condition known as lactic acidosis. This is more likely in older adults, or individuals with kidney or liver issues, dehydration, heart failure, heavy alcohol use, or those undergoing surgery or procedures involving iodinated contrast. Symptoms include unusual tiredness, dizziness, severe drowsiness, muscle pain, fast or difficult breathing, irregular heartbeat, and stomach pain with nausea or vomiting. Immediate medical attention is required if these symptoms occur.
Heart Health Concerns: While more research is needed, studies suggest that sulfonylureas, similar to glipizide, may increase the risk of fatal heart problems. Report any signs of heart attack or heart failure, such as chest pain, trouble breathing, or sudden weight gain, to your healthcare provider promptly. Hospitalization and discontinuation of the medication might be necessary.
Hypoglycemia (Low Blood Sugar): This medication can cause dangerously low blood sugar levels, especially when combined with other diabetes drugs like insulin or if meals are skipped. Symptoms include shakiness, fast heartbeat, sweating, confusion, or intense hunger. Monitoring blood sugar levels is advised, particularly when starting the medication. Risks increase with alcohol consumption, intense exercise, or in older adults with kidney or liver issues.
Vitamin B12 Deficiency: Long-term use of glipizide/metformin may lower vitamin B12 levels, potentially leading to anemia. Providers should check vitamin B12 levels every 2-3 years and may recommend supplements if necessary. Report symptoms like low energy, dizziness, or numbness in extremities to your healthcare provider.
Contraindications:
- Do not use this medication if you have severe kidney problems or diabetic ketoacidosis, as it may pose serious health risks.
Always discuss your complete medical history and any current medications with your healthcare provider before starting glipizide/metformin. Stay informed about all potential risks and consult your provider with any concerns.
Glipizide-metformin Hcl Side Effects
Common side effects:
- Nausea
- Diarrhea
- Headaches
- Muscle aches
- Stomach upset
- Dizziness
- Symptoms resembling a cold or flu
Less common but important to monitor:
- Low blood sugar (hypoglycemia)
Serious side effects:
- Persistent nausea
- Easy bruising or bleeding
- Signs of infection
- Severe stomach or abdominal pain
- Yellowing of eyes or skin
- Dark urine
- Lactic acidosis
- Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
Glipizide-metformin Hcl Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- Acetrizoic Acid
- Diatrizoate
- Ethiodized Oil
- Iohexol
- Iobenzamic Acid
- Iobitridol
- Iocarmic Acid
- Iocetamic Acid
- Iodamide
- Iodipamide
- Iodixanol
- Iodohippuric Acid
- Iodopyracet
- Iodoxamic Acid
- Ioglicic Acid
- Ioglycamic Acid
- Iomeprol
- Iopamidol
- Iopanoic Acid
- Iopentol
- Iophendylate
- Iopromide
- Iopronic Acid
- Ioseric Acid
- Iosimide
- Iotasul
- Iothalamate
- Iotrolan
- Iotroxic Acid
- Ioxaglate
- Ioxitalamic Acid
- Ipodate
- Metrizamide
- Metrizoic Acid
- Tyropanoate Sodium
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Acarbose
- Aspirin
- Balofloxacin
- Besifloxacin
- Bupropion
- Capmatinib
- Ceritinib
- Chloroquine
- Ciprofloxacin
- Dasabuvir
- Desmopressin
- Disopyramide
- Dofetilide
- Dolutegravir
- Dulaglutide
- Enoxacin
- Entacapone
- Fleroxacin
- Flumequine
- Gatifloxacin
- Gemifloxacin
- Hydroxychloroquine
- Ioversol
- Lanreotide
- Levofloxacin
- Lixisenatide
- Lomefloxacin
- Metreleptin
- Moxifloxacin
- Nadifloxacin
- Norfloxacin
- Octreotide
- Ofloxacin
- Ombitasvir
- Paritaprevir
- Pasireotide
- Pazufloxacin
- Pefloxacin
- Pioglitazone
- Porfimer
- Prulifloxacin
- Ritonavir
- Rufloxacin
- Sitagliptin
- Sparfloxacin
- Tafenoquine
- Thioctic Acid
- Tosufloxacin
- Vandetanib
Interactions with low risk that usually do not require a change in therapy:
- Acebutolol
- Aminolevulinic Acid
- Atenolol
- Betaxolol
- Bisoprolol
- Bitter Melon
- Carteolol
- Carvedilol
- Celiprolol
- Cimetidine
- Clarithromycin
- Colesevelam
- Cyclosporine
- Esmolol
- Fenugreek
- Furazolidone
- Gemfibrozil
- Glucomannan
- Guar Gum
- Iproniazid
- Isocarboxazid
- Labetalol
- Levobunolol
- Linezolid
- Methylene Blue
- Metipranolol
- Metoprolol
- Moclobemide
- Nadolol
- Nebivolol
- Nialamide
- Oxprenolol
- Patiromer
- Penbutolol
- Phenelzine
- Pindolol
- Practolol
- Procarbazine
- Propranolol
- Psyllium
- Ranitidine
- Ranolazine
- Rasagiline
- Rifampin
- Safinamide
- Saxagliptin
- Selegiline
- Sotalol
- Timolol
- Tranylcypromine
- Verapamil
- Voriconazole
What happens if you take glipizide and metformin together?
Taking glipizide and metformin together is a common practice for managing type 2 diabetes. These medications work in different ways to help control blood sugar levels. Glipizide stimulates the pancreas to release more insulin, while metformin decreases glucose production in the liver and improves insulin sensitivity. When used together, they can provide a synergistic effect, leading to better blood sugar control. However, there is an increased risk of hypoglycemia (low blood sugar), so monitoring blood sugar levels regularly and following the healthcare provider's instructions is important.
Does glipizide metformin cause weight gain?
Glipizide, which is a sulfonylurea, can potentially cause weight gain as a side effect. Metformin, on the other hand, is generally associated with weight neutrality or even weight loss. When combined, the effect on weight can vary depending on the individual's response to the medication. It is important for patients to discuss any concerns about weight changes with their healthcare provider.
What does glipizide metformin do?
Glipizide metformin is a combination medication used to help control blood sugar levels in individuals with type 2 diabetes. Glipizide works by stimulating the pancreas to release insulin, while metformin decreases glucose production in the liver and improves insulin sensitivity. Together, they help manage blood sugar levels more effectively.
Which type 2 diabetes medications cause weight gain?
Certain medications used to treat type 2 diabetes can lead to weight gain. These include:1. Insulin: While essential for managing blood sugar, insulin can sometimes cause weight gain.2. Sulfonylureas: Medications like glipizide, glyburide, and glimepiride can lead to weight gain.3. Thiazolidinediones (TZDs): Drugs such as pioglitazone and rosiglitazone are associated with weight gain.Patients should discuss any concerns about weight gain with their healthcare provider to explore alternative treatments or strategies to manage weight.
Why are doctors no longer prescribing metformin?
Doctors may still prescribe metformin, as it remains a common and effective treatment for type 2 diabetes. However, there have been some concerns about impurities found in certain batches of metformin, specifically NDMA (N-nitrosodimethylamine), which is a potential carcinogen. This has led to recalls of specific lots of the medication. Additionally, some patients may experience side effects or have contraindications that make other medications more suitable. It is important for patients to discuss any concerns with their healthcare provider to determine the best treatment plan for their individual needs.