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This medication requires careful attention regarding its usage due to potential risks and necessary precautions. Below are important safety guidelines and warnings:

• Pregnancy Alert: This medication can cause severe harm, possibly fatal, to an unborn baby. It should not be used during pregnancy. Effective birth control methods should be employed while on this medication. If you plan to become pregnant, are pregnant, or suspect you might be, contact your healthcare provider immediately to discuss safer alternatives.

• Low Blood Pressure: This drug may cause a significant drop in blood pressure, potentially leading to dizziness, fatigue, or lightheadedness, especially when starting the treatment or increasing the dose. It is important to stay hydrated. If experiencing symptoms, sit down slowly and inform your healthcare provider. If a fall occurs resulting in a head injury, seek medical assistance promptly. Risk factors include dehydration, prolonged diarrhea or vomiting, low sodium levels, high doses of diuretics, and dialysis.

• Allergic Reactions: Individuals with a history of asthma or allergies may have an increased risk of allergic reactions. Seek emergency medical help if symptoms such as rash, hives, difficulty breathing, swallowing, or facial swelling occur.

• Lupus: In rare instances, this medication can worsen or cause new lupus symptoms. Notify your healthcare provider if you observe a facial rash or experience extreme fatigue.

• Electrolyte, Blood Sugar, and Cholesterol Changes: The medication may alter levels of sodium, potassium, magnesium, and blood sugar, or impact cholesterol. Regular blood tests may be necessary to monitor these levels. Report symptoms like rapid heartbeat, fatigue, muscle pain or cramps, reduced urination, nausea, or vomiting to your healthcare team.

• Kidney Damage: The medication may impair kidney function, especially in individuals with severe congestive heart failure or pre-existing kidney issues. Regular lab tests may be needed to monitor kidney health. Report any urinary issues to your healthcare provider. Contributing factors include severe heart failure, kidney problems, dehydration, and concurrent use of other kidney-impacting medications.

• Vision Problems: Some individuals might experience visual changes due to this medication. Report any changes in vision or eye pain immediately. Discontinuation might be necessary, and in some cases, surgery could be required to prevent permanent vision loss. Risks include allergies to sulfa or penicillin.

Contraindications:

• Avoid using this medication in combination with aliskiren (Tekturna) in diabetic individuals.
• Not suitable for individuals who do not produce urine.
• Contraindicated for those with allergies to sulfa medications or ARBs.

These precautions are essential for ensuring safe and effective use of the medication. Always consult with your healthcare provider for personalized advice and guidance.

When taking this medication, you might experience some common side effects such as dizziness, tiredness, and muscle pain. These effects are generally mild and often subside as your body adjusts. However, if they persist or worsen, it's advisable to consult a healthcare provider. To mitigate dizziness and lightheadedness, try rising slowly from sitting or lying positions.

In some cases, individuals might encounter other side effects like flu-like symptoms, swelling, nausea, vomiting, chest pain, or an increased heart rate. While these are not as common, it's important to contact your healthcare provider if you notice them, particularly if they become severe.

There are also rare but serious side effects that require immediate medical attention. These include severe allergic reactions characterized by trouble breathing, rash, and swelling of the face, arms, or legs. Additionally, be alert for signs of dangerously low blood pressure, such as dizziness, lightheadedness, and pale skin. Liver issues can manifest as yellowing of the skin or eyes, stomach pain, and confusion, while serious kidney problems might present as reduced urination and swelling in the extremities. If you experience any of these severe symptoms, seek urgent medical care. Always communicate with your healthcare provider about any other effects that may not be listed here.