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Chlordiazepoxide carries several important safety warnings and precautions that should be carefully considered before use. Here is a summary of the key points for your awareness:

• Risk of Abuse and Addiction: Chlordiazepoxide can be habit-forming. Misuse of this medication can lead to serious effects, including overdose and death. It is crucial to use the smallest effective dose for the shortest duration necessary as advised by your healthcare provider.

• Interactions with Other Substances: Combining chlordiazepoxide with alcohol or other drugs that cause drowsiness or breathing difficulties, particularly opioids like codeine or hydrocodone, can result in severe side effects such as extreme drowsiness, slowed breathing, coma, or death.

• Dependence and Withdrawal: Prolonged use can lead to physical dependence. If you suddenly stop taking chlordiazepoxide or reduce the dose too quickly, withdrawal symptoms such as nausea, tremors, anxiety, and more severe symptoms like seizures and depression may occur. To minimize these risks, it is important to follow your provider’s plan for gradually reducing your dosage.

• Effects on Mental Alertness: This medication may impair your ability to focus and react. Until you are familiar with how it affects you, avoid activities that require full alertness, like driving or operating heavy machinery. Be particularly cautious if taking other medications that also reduce alertness.

• Pregnancy Warnings: Use of chlordiazepoxide during pregnancy may harm your unborn child, potentially causing breathing problems, excessive sleepiness, and withdrawal symptoms in the newborn. Discuss the potential risks with your healthcare provider if you are pregnant or planning to become pregnant.

• Contraindications: Chlordiazepoxide should not be used if you have certain medical conditions, such as glaucoma, enlarged prostate, or bladder obstruction. Consult with your healthcare provider if you have any of these conditions before starting the medication.

• Emergency Situations: Seek immediate medical attention if you experience severe side effects such as slow or shallow breathing, unusual lightheadedness, severe drowsiness, dizziness, or difficulty waking up.

It is vital to adhere strictly to your healthcare provider’s guidance and report any adverse effects or concerns promptly.

Common side effects:

• dizziness
• drowsiness
• confusion
• blurred vision
• dry eyes
• dry mouth
• constipation
• nausea
• abdominal bloating
• trouble urinating

Less common but important to monitor:

• decreased sweating
• hot or flushed skin
• irregular heartbeat
• loss of coordination
• mental changes such as confusion or unusual excitement
• difficulty speaking
• uncontrollable muscle movements
• changes in libido
• changes in menstrual cycles
• trouble with balance

Serious side effects:

• excessive drowsiness
• difficulty breathing
• eye pain
• vision changes
• signs of an allergic reaction such as rash, swelling, or trouble breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Flumazenil
• Potassium tablets/capsules

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Opioids (e.g., codeine, hydrocodone)
• Other sedatives (e.g., Alprazolam, Zolpidem)
• Muscle relaxants (e.g., Carisoprodol)
• Certain antihistamines (e.g., Cetirizine, diphenhydramine)
• Azole antifungals (e.g., Ketoconazole, Itraconazole)
• Cimetidine
• Disulfiram
• Smoking