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This medication has specific safety warnings and contraindications that are important for your health. Please read the following information carefully and consult your healthcare provider if you have any questions or concerns.

• Dizziness and Drowsiness: Hyoscyamine may cause sleepiness, dizziness, and blurred vision. Avoid driving or engaging in activities that require full attention until you know how the medication affects you.

• Mental Changes: This medication can alter your mood, cognitive functions, and behavior, leading to confusion, memory issues, or disorientation. Severe symptoms may include agitation, hallucinations, or euphoria, and in rare cases, coma. These effects usually subside within 12 to 48 hours after discontinuation. Notify your provider immediately if you notice any mental changes. Those aged 65 or older and individuals with mental health conditions are at higher risk.

• Increased Heart Rate: Hyoscyamine may raise your heart rate, worsening conditions like heart failure, previous heart attacks, or high blood pressure. Report any changes in heart rate or symptoms like a pounding or racing heart to your provider. Individuals with heart problems or high blood pressure should exercise caution.

• Autonomic Function Changes: This medication can affect involuntary body functions, potentially slowing gut muscles, leading to constipation, reducing saliva or sweat production, and increasing the risk of heat stroke. It can also impact heartbeat and vision. Report any bodily function changes to your provider. Do not take hyoscyamine if you have a fever without consulting your provider. Those aged 65 or older should take extra precautions.

• Urinary Issues: Use hyoscyamine cautiously if you have prostate problems, as it may exacerbate difficulty urinating.

• Gut Problems: Consult your provider if you have had a colostomy or similar procedures before using hyoscyamine for diarrhea, as it might indicate a gut blockage, making the medication harmful.

Contraindications

Do not use this medication if you have any of the following conditions, as it can pose serious health risks:

• Glaucoma
• Urinary tract blockage
• Stomach or intestinal blockage
• Long-term constipation
• Unstable heart or bleeding problems
• Severe ulcerative colitis with toxic megacolon
• Myasthenia gravis

Always seek medical advice from your healthcare provider to ensure safe use of this medication.

When taking this medication, you might experience some common side effects that are generally mild in nature. These include dizziness, drowsiness, blurred vision, dry mouth, headache, trouble sleeping, constipation, flushing, dry skin, and decreased sweating. To alleviate dry mouth, consider using sugarless gum or candy, ice chips, or a saliva substitute, and ensure you stay hydrated.

However, there are more serious side effects that you should be aware of. If you encounter mental or mood changes such as confusion or unusual excitement, a fast or irregular heartbeat, difficulty urinating, decreased sexual ability, loss of coordination, trouble speaking, or vomiting, it is important to contact your healthcare provider promptly.

In rare cases, this medication can lead to severe eye pain, swelling, redness, or vision changes, such as seeing rainbows around lights at night. These require immediate medical assistance.

Serious allergic reactions are also rare but can manifest through symptoms like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. Seek urgent medical help if you notice any of these signs. While many people tolerate this medication well, staying informed about potential side effects is crucial for your safety.

When taking this medication, it's important to be aware of potential drug interactions. Some drugs that could interact include certain antifungals like ketoconazole and itraconazole, bisphosphonates such as alendronate and risedronate, corticosteroids like prednisone, as well as digoxin, potassium supplements, and pramlintide. Additionally, medications that cause drowsiness might increase side effects, including opioid pain relievers (e.g., codeine, hydrocodone), alcohol, cannabis, sleep aids (e.g., alprazolam, lorazepam, zolpidem), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), and antihistamines (e.g., cetirizine, diphenhydramine).

Furthermore, certain medications should not be used together with this drug, such as ambenonium, bepridil, bromopride, cisapride, dronedarone, and others due to increased risk of serious side effects. In some cases, combining this medication with others like aclidinium, alfentanil, alprazolam, among many others, may require careful management by your doctor, potentially adjusting doses to minimize interactions.

It's crucial to inform your healthcare provider of all medications and supplements you're taking, including over-the-counter products, vitamins, and herbal supplements. This medication may also interfere with some lab tests, leading to inaccurate results, so ensure that all health professionals involved in your care are informed about your medication use.