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Dexmethylphenidate carries the risk of significant heart and blood pressure issues if misused or abused, which could potentially be fatal. It has the potential for dependence and should be used with caution, particularly in individuals with mental health disorders or a history of substance misuse.

Key precautions include:

• Individuals with a personal or family history of substance use disorders should inform their healthcare provider before starting this medication.
• Do not increase the dosage, frequency, or duration of use beyond what your healthcare provider prescribes, as this can lead to reduced efficacy, drug dependence, or unusual thoughts and behaviors.
• If you have been taking this medication for an extended period or in high doses, your doctor may continue to monitor your condition after cessation to ensure safety.

Always adhere strictly to the prescribed guidelines and consult your healthcare provider with any concerns.

You might experience some common side effects, such as difficulty sleeping, nervousness, nausea, stomach pain, headaches, loss of appetite, weight loss, or dizziness. These are generally mild, but if they persist or worsen, it's important to consult with a healthcare provider. Regularly check your blood pressure, as this medication can cause an increase. Report any significant rise to your healthcare provider.

Be aware of more serious side effects that need prompt medical attention. These include signs of blood flow issues in fingers or toes, such as coldness, numbness, pain, or color changes, unusual wounds, or a fast, pounding, or irregular heartbeat. Mental or mood changes, such as agitation, aggression, mood swings, abnormal thoughts, or suicidal thoughts, should also be reported immediately. Uncontrolled muscle movements, sudden outbursts, or vision changes like blurred vision require urgent medical consultation.

Seek immediate medical help for severe side effects like fainting, seizures, heart attack symptoms (chest, jaw, or left arm pain, shortness of breath, unusual sweating), or stroke symptoms (weakness on one side of the body, trouble speaking, sudden vision changes, confusion). Males, including young boys and teens, should be cautious of a rare but serious side effect of a prolonged or painful erection lasting over four hours, as it requires immediate medical intervention to prevent permanent damage.

A serious allergic reaction is rare but requires urgent care if symptoms like rash, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing occur. This summary does not include all possible side effects. If you notice any other unusual symptoms, consult your healthcare provider.

Avoid using this medication with MAO inhibitors, as it can result in a severe, potentially life-threatening interaction. MAO inhibitors include drugs like isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, and Tranylcypromine. You should not take most MAO inhibitors for two weeks before starting this medication. Consult your doctor for guidance on when to begin or discontinue this medication.

Dexmethylphenidate is closely related to Methylphenidate, so you should not take any medicines containing methylphenidate while on dexmethylphenidate.

This medication can affect certain medical or laboratory tests, such as brain scans for Parkinson's disease, leading to inaccurate results. Ensure that all medical personnel involved in your care are aware that you are taking this medication.