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Diclofenac, a nonsteroidal anti-inflammatory drug, carries certain risks and precautions that must be considered before use. Here is a summary of important safety information:

• Cardiovascular Risk: Diclofenac may infrequently increase the likelihood of a heart attack or stroke, potentially occurring at any time during treatment. This risk is heightened with prolonged use and is more pronounced in older adults or individuals with pre-existing heart conditions or factors such as smoking, family history, high blood pressure, or diabetes. It is critical not to use diclofenac immediately before or after coronary artery bypass graft (CABG) surgery.

• Gastrointestinal Risk: There is a rare but serious risk of bleeding in the stomach or intestines, which could be life-threatening. This can occur without any prior symptoms. Older adults may be particularly susceptible to this adverse effect.

• Emergency Symptoms: Discontinue use and seek immediate medical attention if you experience persistent stomach or abdominal pain, black or bloody stools, vomit resembling coffee grounds, chest, jaw, or left arm pain, shortness of breath, unusual sweating, sudden confusion, weakness on one side of the body, abrupt changes in vision, or difficulty speaking.

• Consultation: It is important to discuss the potential benefits and risks of diclofenac with your healthcare provider to ensure it is suitable for your condition.

When using this medication, some individuals might experience skin irritation or redness at the application site. These are usually mild, but if the irritation persists or worsens, it is advisable to consult a healthcare professional. It's also important to monitor your blood pressure regularly, as this medication can cause an increase. If you notice high blood pressure readings, seek advice from a healthcare provider.

In rare cases, this medication may lead to serious side effects, such as signs of kidney problems, including changes in urination, or symptoms of heart failure like swelling in the ankles or feet, unusual fatigue, or sudden weight gain. Seek immediate medical attention if you experience any of these symptoms.

Additionally, although extremely rare, there is a possibility of developing severe liver disease, which can be potentially fatal. Symptoms indicating liver damage include persistent nausea or vomiting, loss of appetite, abdominal pain, yellowing of the eyes or skin, and dark urine. Prompt medical intervention is critical if these occur.

A very serious allergic reaction to this drug is unlikely, but it is important to be aware of the symptoms, such as fever, swollen lymph nodes, rash, itching or swelling particularly of the face, tongue, or throat, severe dizziness, or difficulty breathing. Immediate medical help is essential if you experience these reactions.

This summary does not cover all possible side effects. If you notice any other unusual reactions, consult your healthcare provider for further guidance.