Odefsey Coupons & Savings Card – Discount Prices from $3875.81

The following safety information outlines critical warnings and risks associated with the use of Odefsey. It is vital to understand these warnings and consult your healthcare provider if you have any concerns or questions.

• Worsening of Hepatitis B: Discontinuing Odefsey can lead to a severe flare-up of hepatitis B. Do not stop taking Odefsey unless advised by your healthcare provider. If instructed to stop or switch medications, ensure regular lab tests are conducted to monitor liver function and hepatitis B virus (HBV) levels.

• Liver Problems and Toxicity: Odefsey, which includes emtricitabine and tenofovir, may cause a serious liver condition known as lactic acidosis with hepatic steatosis, particularly in individuals with liver disease or infection. It is not recommended for those with moderate to severe liver conditions. Symptoms such as loss of appetite, abdominal pain, muscle pain, rapid breathing, fatigue, and sudden weakness require immediate medical attention. Regular liver function tests are necessary during treatment.

• Depression and Mood Changes: There is a risk of mood alterations, including depression and suicidal thoughts, with Odefsey. Contact your healthcare provider if you experience mood changes, and seek immediate help if you have thoughts of self-harm.

• Kidney Problems: Odefsey can lead to kidney issues, either shortly after starting or over time. Avoid combining it with other nephrotoxic medications, such as high-dose NSAIDs. Regular kidney function tests are recommended.

• Bone Problems: The medication may reduce bone mineral density, increasing the risk of osteoporosis and fractures. Calcium and vitamin D supplements may be advised. Your provider might conduct bone density tests if fractures occur or if you are at risk for bone issues.

• Immune Reconstitution Syndrome: As your immune system strengthens while on Odefsey, it may cause inflammation by fighting underlying infections. Consult your provider if you experience fever, breathing difficulties, or sudden health changes after beginning treatment.

Please ensure you follow these guidelines and maintain open communication with your healthcare provider to manage your health effectively while on Odefsey.

When taking Odefsey, it's important to be aware of potential interactions with other medications and substances, as these can affect how well Odefsey works or increase the risk of side effects. Here are some key points to consider:

Medications to Avoid:

• Proton Pump Inhibitors (PPIs): Drugs like Omeprazole, esomeprazole, and others can reduce the effectiveness of Odefsey by lowering rilpivirine levels. Therefore, using PPIs with Odefsey is not recommended.

• Certain Anticonvulsants: Medications such as Carbamazepine, Oxcarbazepine, Phenobarbital, and Phenytoin can decrease rilpivirine levels, potentially leading to treatment failure. Avoid combining these with Odefsey.

• Specific Antibiotics: Rifampin and rifapentine can lower rilpivirine concentrations, which may reduce Odefsey's effectiveness. These should not be used concurrently with Odefsey.

• St. John's Wort: This herbal supplement can decrease rilpivirine levels, potentially leading to treatment failure. It's advisable to avoid St. John's Wort while on Odefsey.

Medications Requiring Special Timing:

• Antacids: Products containing aluminum, Magnesium Hydroxide, or Calcium Carbonate can interfere with rilpivirine absorption. To minimize this interaction, take antacids at least two hours before or at least four hours after Odefsey.

• H₂-Receptor Antagonists: Drugs like Famotidine, Cimetidine, and ranitidine can also affect rilpivirine levels. If you need to use these, take them at least 12 hours before or at least four hours after Odefsey.

Other Considerations:

• Medications Affecting Kidney Function: Odefsey contains components that are processed by the kidneys. Using it alongside drugs that impact kidney function, such as certain antivirals (e.g., Acyclovir, ganciclovir) or nonsteroidal anti-inflammatory drugs (NSAIDs), may increase the risk of side effects. Consult your healthcare provider before combining these medications.

• QT Prolonging Drugs: Some medications can prolong the QT interval on an ECG, which may lead to heart rhythm issues. While the risk with Odefsey is low at recommended doses, it's important to discuss any medications with known QT prolongation effects with your doctor.

Always inform your healthcare provider about all medications, supplements, and over-the-counter products you are taking. They can provide guidance on potential interactions and help you manage your treatment effectively.