Sitagliptin

Drug Details

Sitagliptin, marketed as Januvia, is a prescription medication designed to help manage Type 2 diabetes in adults. It is most effective when used in combination with a healthy diet and regular exercise. Sitagliptin belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors or gliptins. This medication works by enhancing the levels of natural hormones called incretins. Incretins play a crucial role in regulating blood sugar by boosting insulin release, especially after meals, and reducing the amount of sugar produced by the liver. By effectively controlling blood sugar levels, sitagliptin helps prevent complications associated with diabetes, such as kidney damage, vision problems, nerve issues, and cardiovascular events like heart attack or stroke. Taken orally, usually once a day, sitagliptin is generally well-tolerated, with common side effects including minor symptoms like a stuffy or runny nose, sore throat, and headache. Always consult with a healthcare professional for personalized medical advice before starting any new medication.