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Acarbose is a medication used to help manage blood sugar levels in individuals with diabetes. It is important to be aware of potential risks and necessary precautions when using this medication. Acarbose can interact with various other medicines and supplements, which may affect how it works or increase the risk of certain side effects. You should always inform your doctor or pharmacist about any other prescribed or over-the-counter medicines, vitamins, or herbal supplements you are taking. Certain medications, including some antibiotics, antidiabetes drugs, and digestive enzyme products such as amylase and pancreatin, may require special adjustments if used together with acarbose. Products containing charcoal and other medicines like pramlintide can also interact with acarbose.

Beta blocker medications, such as metoprolol, propranolol, and certain glaucoma eye drops like timolol, may make it harder for you to recognize some symptoms of low blood sugar, such as a rapid or pounding heartbeat. However, other symptoms like dizziness, hunger, or sweating are not affected by these medications. Additionally, medicines such as warfarin and a number of other prescription drugs listed may either increase the risk of side effects or require dosage adjustments when combined with acarbose.

When starting, stopping, or changing any medications, it is important to consult your healthcare provider to understand how the change may impact your blood sugar control. Regularly monitoring your blood sugar as directed and promptly reporting any symptoms of high or low blood sugar to your doctor is essential. Your healthcare provider may need to adjust your diabetes medication, diet, or exercise program based on your response to treatment. By maintaining ongoing communication with your medical team and following their instructions, you can help ensure the safe and effective use of acarbose.

Common side effects:

• Excessive gas
• Diarrhea
• Abdominal pain

Less common but important to monitor:

• Rash
• Itching
• Skin redness
• Swelling

Serious side effects:

• Ongoing nausea
• Ongoing vomiting
• Loss of appetite
• Yellowing of the eyes or skin (jaundice)
• Stomach pain
• Dark urine
• Pneumatosis cystoides intestinalis
• Persistent diarrhea
• Constipation
• Blood in the stool
• Mucus in the stool
• Low blood sugar (hypoglycemia)
• Sweating
• Shaking
• Fast heartbeat
• Hunger
• Blurred vision
• Dizziness
• Tingling in the hands or feet
• Allergic reactions (including swelling of the face, tongue, or throat, severe dizziness, difficulty breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Acetohexamide
• Aspirin
• Balofloxacin
• Besifloxacin
• Chloroquine
• Chlorpropamide
• Ciprofloxacin
• Digoxin
• Enoxacin
• Fleroxacin
• Flumequine
• Gatifloxacin
• Gemifloxacin
• Gliclazide
• Glipizide
• Glyburide
• Hydroxychloroquine
• Lanreotide
• Levofloxacin
• Lomefloxacin
• Moxifloxacin
• Nadifloxacin
• Norfloxacin
• Octreotide
• Ofloxacin
• Pasireotide
• Pazufloxacin
• Pefloxacin
• Pioglitazone
• Prulifloxacin
• Rufloxacin
• Sitagliptin
• Sparfloxacin
• Thioctic Acid
• Tolazamide
• Tolbutamide
• Tosufloxacin

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Acebutolol
• Atenolol
• Betaxolol
• Bisoprolol
• Bitter Melon
• Carteolol
• Carvedilol
• Celiprolol
• Esmolol
• Fenugreek
• Furazolidone
• Glucomannan
• Guar Gum
• Iproniazid
• Isocarboxazid
• Labetalol
• Levobunolol
• Linezolid
• Methylene Blue
• Metipranolol
• Metoprolol
• Moclobemide
• Nadolol
• Nebivolol
• Nialamide
• Oxprenolol
• Penbutolol
• Phenelzine
• Pindolol
• Practolol
• Procarbazine
• Propranolol
• Psyllium
• Rasagiline
• Safinamide
• Selegiline
• Sotalol
• Timolol
• Tranylcypromine
• Warfarin

Interactions with low risk that usually do not require a change in therapy:

• Charcoal products
• Digestive enzyme products (such as amylase, pancreatin)
• Pramlintide