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When taking this medication, some individuals might experience nausea, vomiting, headache, bloating, breast tenderness, or swelling of the ankles/feet due to fluid retention. Weight changes can also occur. In the initial months, vaginal bleeding between periods or changes in the menstrual cycle, such as missed or irregular periods, are possible. These effects are generally mild, but if they persist or worsen, it is important to consult a healthcare provider.

This medication may also lead to an increase in blood pressure, so regular monitoring is advised. If serious side effects develop, such as lumps in the breast, significant mood changes, severe abdominal pain, or unusual vaginal bleeding, contact a healthcare professional immediately. Rarely, this medication can cause serious blood clotting issues, potentially leading to heart attack, stroke, or clots in the lungs or legs. Seek urgent medical attention if symptoms like chest pain, sudden dizziness, severe headaches, or changes in vision occur.

While severe allergic reactions are rare, they may present with symptoms like rash, swelling, or difficulty breathing, necessitating immediate medical intervention. This summary does not cover all possible side effects. If any unlisted effects occur, it is advisable to reach out to a healthcare provider for further guidance.

Certain medications can interact with this drug, so it's important to be aware of them and discuss with your healthcare provider. Some of these include aromatase inhibitors like Anastrozole and Exemestane, as well as other drugs such as fezolinetant, ospemifene, Tamoxifen, Tizanidine, and Tranexamic Acid.

Additionally, some medications may reduce the effectiveness of hormonal birth control by lowering the levels of birth control hormones in your body, potentially leading to pregnancy. These include griseofulvin, Modafinil, certain antibiotics like Rifampin and Rifabutin, and herbal supplements such as St. John's wort. Other examples include seizure medications (such as barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, Topiramate) and certain HIV medications (such as nelfinavir and Nevirapine).

If you start any new medication, inform your doctor and consider using an additional form of reliable birth control. Also, report any unexpected spotting or breakthrough bleeding to your healthcare provider, as these could indicate that your birth control is not fully effective.

Finally, this medication may affect the results of some laboratory tests, including those assessing blood clotting factors and thyroid function. It is important for lab personnel and all your doctors to know that you are taking this medication to avoid misinterpretation of test results.