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Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) that carries several important safety warnings. It's essential to be aware of the potential risks and take precautions if you are considering using this medication. Below are key safety points to consider:

• Heart Attack and Stroke Risks: Meloxicam may increase the risk of heart attack or stroke, which can occur at any time during treatment. This risk is higher in individuals with heart disease, those who smoke, or have conditions like high blood pressure or diabetes. Avoid using meloxicam right before or after coronary artery bypass graft (CABG) surgery. Seek immediate medical attention if you experience symptoms such as chest pain, shortness of breath, or sudden weakness on one side of the body.

• Stomach and Intestinal Bleeding: This drug may rarely cause severe and potentially fatal bleeding from the stomach or intestines, which can occur without warning. Older adults and those with a history of stomach bleeding are at higher risk. If you experience persistent stomach/abdominal pain, bloody or black stools, or vomit that resembles coffee grounds, stop taking meloxicam and seek medical help immediately.

• High Blood Pressure and Heart Failure: Meloxicam can elevate blood pressure or increase the risk of heart failure by causing fluid retention. Individuals with a history of heart problems should discuss this risk with their healthcare provider. Monitor your blood pressure while on meloxicam and report any changes or symptoms such as chest pain, swelling, or difficulty breathing.

• Liver and Kidney Issues: Rarely, meloxicam can lead to serious liver or kidney damage. This risk is higher in those with pre-existing liver or kidney conditions, or who are on certain blood pressure medications. Be alert for symptoms like abdominal swelling, jaundice, or changes in urine and seek prompt medical attention if they occur.

• Severe Allergic Reactions and Asthma: Allergic reactions to meloxicam, including anaphylaxis, can be life-threatening. Individuals with allergies to aspirin or other NSAIDs should use caution. Also, meloxicam may exacerbate asthma symptoms, particularly in those with known sensitivities to aspirin or NSAIDs. Seek immediate medical assistance if you experience hives, difficulty breathing, or throat tightness.

• Risks During Pregnancy: Taking meloxicam during the second half of pregnancy can harm the unborn baby or cause complications during delivery. Pregnant individuals or those planning to become pregnant should consult their healthcare provider to weigh the risks and benefits.

• Contraindications: Do not use meloxicam if you have a history of asthma or allergic reactions after taking aspirin or other NSAIDs, or if you have undergone recent heart surgery.

Always discuss your health conditions and any other medications you are taking with your healthcare provider before starting meloxicam to ensure it is safe and appropriate for your use. If you suspect an overdose or experience severe side effects, seek emergency medical attention immediately.

When taking this medication, some individuals may experience mild side effects such as stomach upset, diarrhea, headache, joint pain, or flu-like symptoms. These are usually not a cause for concern, but if they persist or worsen, it's advisable to consult with a healthcare provider. Additionally, some people may experience swelling, urinary tract infections, or constipation.

It's important to be aware that this medication can potentially raise blood pressure. Regular monitoring of blood pressure is recommended, and any significant increases should be discussed with a healthcare provider. While serious side effects are rare, they can occur. These include symptoms like easy bruising or bleeding, mental or mood changes, signs of kidney problems such as a change in urine output, and symptoms of heart failure like swelling in the ankles or feet, unusual tiredness, or sudden weight gain.

There is a rare but serious risk of liver damage associated with this medication. Symptoms to watch for include persistent nausea and vomiting, loss of appetite, dark urine, abdominal pain, and yellowing of the skin or eyes. Immediate medical attention is necessary if these occur. Also, in rare cases, serious allergic reactions can happen, presenting symptoms like fever, swollen lymph nodes, rash, itching, swelling, severe dizziness, or trouble breathing. If you experience any of these, seek medical help promptly. If you notice other side effects not mentioned here, contact your healthcare provider for further guidance.

Certain medications can interact with this drug and may require caution. These include aliskiren, ACE inhibitors like captopril and lisinopril, angiotensin II receptor blockers such as losartan and valsartan, cidofovir, lithium, high doses of methotrexate, and diuretics like furosemide. Additionally, this medication can increase bleeding risk if combined with other drugs that have similar effects, such as anti-platelet medications like clopidogrel and blood thinners including dabigatran, enoxaparin, or warfarin.

If you are taking the liquid form of meloxicam, inform your doctor if you also use sodium polystyrene sulfonate. Be mindful of all prescription and over-the-counter medications, as many contain pain relievers or fever reducers (such as aspirin, NSAIDs like celecoxib, ibuprofen, or ketorolac) that are similar to meloxicam and may heighten side effects when used together. However, if your doctor has advised you to take low-dose aspirin to prevent heart attack or stroke, continue unless instructed otherwise. Always consult your doctor or pharmacist for more guidance.