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The following information outlines critical safety warnings associated with the use of Trileptal (oxcarbazepine). It's important to carefully review these warnings and discuss any concerns with your healthcare provider.

• Low Blood Sodium Levels: Trileptal (oxcarbazepine) can lead to low sodium levels in the blood, although this is uncommon. This side effect often occurs within the first three months of treatment. Symptoms might not be apparent, so regular monitoring of sodium levels through blood tests is advised. Seek immediate medical attention if you experience symptoms like weakness, confusion, headache, or memory issues, as these may indicate a medical emergency. Higher risk groups include older adults and those on medications that also lower sodium levels.

• Severe Allergic and Skin Reactions: There is a possibility of severe allergic reactions to Trileptal, including life-threatening conditions such as facial swelling and anaphylaxis. Inform your healthcare provider if you are allergic to carbamazepine (Tegretol). Increased risk is noted in individuals of Asian descent or those with certain genetic predispositions.

• Risk of Suicidal Thoughts: Trileptal (oxcarbazepine) can increase the risk of suicidal thoughts or behaviors, potentially occurring as soon as one week after starting the medication. If you or others notice suicidal ideation or unusual behaviors such as anxiety, restlessness, or irritability, seek medical help immediately. Individuals with a history of depression or mental health disorders are at greater risk.

• Cognitive and Motor Impairment: This medication may affect brain function, leading to issues with speech, concentration, and coordination. It can also cause significant dizziness and drowsiness, affecting your ability to perform tasks that require focus. The risk is heightened if you are taking high doses, consuming alcohol, or using other medications that cause sleepiness. Consult your healthcare provider if you experience excessive drowsiness.

• Increased Risk of Seizures: While effective in controlling seizures, Trileptal can occasionally exacerbate them, particularly in children. If seizures worsen, discontinue use and seek immediate medical assistance.

• Withdrawal: Abruptly stopping Trileptal can increase seizure risk. Always consult your healthcare provider before discontinuing the medication; they will guide you in gradually reducing the dose to lessen seizure risk.

• Contraindications: Do not use this medication if you have a known allergy to Aptiom (eslicarbazepine). Always discuss any past allergic reactions with your healthcare provider before starting Trileptal.

This information aims to ensure the safe use of Trileptal (oxcarbazepine) and must be used in consultation with a healthcare professional.

When taking this medication, some individuals may experience common side effects such as dizziness, nausea, headache, vomiting, and diarrhea. These symptoms are usually mild, but if they persist or worsen, consulting a healthcare provider is advisable. Other reported side effects include constipation, heartburn, poor balance or coordination, and nervousness. Upper respiratory symptoms like a runny nose and sore throat may also occur.

It is important to be aware of more serious side effects, although they are rare. Immediate medical attention is necessary if you experience serious allergic reactions such as hives, rash, blisters, or swelling of the lips or tongue, which can cause difficulty breathing. The medication may also lead to serious skin reactions, particularly in certain ethnic groups, with symptoms like skin reddening or peeling. Additionally, low sodium levels can manifest as nausea, extreme fatigue, confusion, hallucinations, or seizures, requiring urgent care.

Furthermore, a small number of people may experience mood changes or suicidal thoughts. If such mental health changes are noticed, prompt communication with a healthcare provider is crucial. Lastly, any unusual symptoms or side effects not listed should be reported to a healthcare professional for guidance.

When taking Trileptal (oxcarbazepine), it's important to be aware of potential interactions with other substances. For instance, Orlistat and Trileptal may alter the speed at which medications are removed from your body, potentially impacting their effectiveness. This can particularly affect medications such as cabotegravir, cobicistat, elvitegravir, sofosbuvir, and rilpivirine.

Additionally, Trileptal can reduce the efficacy of hormonal birth control methods like pills, patches, or rings, increasing the risk of pregnancy. Consult your doctor about using an additional reliable form of contraception and inform them if you experience unusual spotting or breakthrough bleeding.

Be cautious when combining Trileptal with substances that cause drowsiness. This includes alcohol, marijuana, certain antihistamines (e.g., Cetirizine, diphenhydramine), sleep or anxiety medications (e.g., Alprazolam, Diazepam, Zolpidem), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), and opioid painkillers (e.g., codeine, hydrocodone). Always check your medicine labels for ingredients that may cause drowsiness and consult your pharmacist for safe use.

Trileptal is similar to eslicarbazepine, so avoid using both simultaneously.

In some cases, using Trileptal with certain medications is not advisable. Your doctor may choose alternatives or adjust dosages. These medications include cabotegravir, doravirine, and rilpivirine. In other situations, although not typically recommended, it may be necessary to use Trileptal with medications such as alfentanil, Amiodarone, cobicistat, and many others. If this is the case, your doctor will manage dosages and monitor any side effects.

Lastly, combining Trileptal with some medications might increase side effect risks, but could still be beneficial. These include felodipine, ginkgo, Lamotrigine, Simvastatin, Valproic Acid, and Verapamil. Your doctor will adjust your treatment plan as needed. Always keep your healthcare providers informed about all medications and supplements you are taking.