Acetaminophen-ibuprofen Coupons & Discount Card - Compare Prices Near You

This medication combines acetaminophen and ibuprofen, which may pose certain risks and require careful consideration before use. Please review the following safety information thoroughly and discuss any concerns with your healthcare provider.

• Heart Attack and Stroke Risk: This medication can elevate the risk of heart attacks and strokes due to potential blood clot formation. This risk is heightened if you have heart issues, are taking high doses, or use the medication for prolonged periods. It is contraindicated for those who have had or will undergo heart surgery. Seek immediate medical help if you experience chest pain, difficulty breathing, sudden weakness on one side, or trouble speaking or walking.

• Liver Damage: Excessive acetaminophen intake can lead to severe liver damage, which can be life-threatening. The daily maximum for adults is generally 4,000 mg, but may be lower based on individual health conditions. Avoid mixing with other acetaminophen-containing products and limit alcohol consumption. Signs of liver issues include dark urine, fatigue, stomach pain, or yellowing of the skin or eyes. Contact your healthcare provider if these arise.

• Kidney Damage: Use of this medication may result in kidney problems, especially if you are older, have diabetes, or are on other kidney-risk medications. Symptoms like changes in urination, fatigue, dry skin, low appetite, and muscle cramps require medical attention.

• Stomach Bleeding and Ulcers: There is a risk of stomach bleeding and ulcers, particularly for older adults, those with a history of bleeding issues, or if combined with alcohol and tobacco use. Seek immediate medical help if you experience fainting, vomiting blood, bloody or dark stools, or severe stomach pain.

• High Blood Pressure and Heart Failure: This medication can cause fluid retention, potentially raising blood pressure or leading to heart failure. Discuss any history of heart problems or blood pressure medication use with your provider.

• Severe Allergic and Skin Reactions: Allergic reactions, including anaphylaxis, may occur. Avoid use if you're allergic to aspirin or other NSAIDs. Seek immediate medical attention if you experience hives, rash, facial swelling, or breathing difficulties.

• Accidental Overdose: Be cautious of combining with other medications containing acetaminophen or ibuprofen, as this increases overdose risks. Symptoms of overdose require urgent medical attention or contacting Poison Control at 1-800-222-1222.

Contraindications: Do not use this medication if you are taking other acetaminophen, ibuprofen, or NSAID-containing drugs, have a history of asthma or allergic reactions to these medications, or after coronary artery bypass graft surgery (CABG).

Always consult with your healthcare provider to fully understand the benefits and risks before starting this medication.

When taking this medication, some people may experience common side effects such as dizziness, nausea, upset stomach, heartburn, skin rashes, headaches, or constipation. These symptoms are usually mild, but if they persist or worsen, consult a healthcare professional for guidance. Diarrhea, vomiting, and gas may also occur, and while not as common, they are generally not severe.

It's important to monitor for serious side effects, although they are rare. These can include symptoms of heart problems such as heart attack or heart failure, indicated by dizziness, tiredness, chest pain, swelling, or sudden weight gain. Stroke symptoms like lightheadedness, blurred vision, and difficulty speaking or walking should be addressed immediately. Additionally, be aware of potential liver issues, which may present as persistent nausea, vomiting, severe abdominal pain, yellowing of the skin or eyes, and dark urine. Kidney problems could manifest through changes in urination, swelling in the lower extremities, or seizures.

In very rare cases, a serious allergic reaction can occur, characterized by fever, swollen lymph nodes, severe dizziness, rash, itching, or trouble breathing. Immediate medical attention is necessary for any signs of a severe allergic reaction, severe asthma attack, or significant skin reaction, such as painful blisters or peeling skin. Always stay vigilant for any unusual symptoms and seek medical assistance when needed.

Certain medications can interact with this drug, influencing its effectiveness or increasing the risk of side effects. It's important to watch for interactions with:

• Blood Pressure Medications: These include Aliskiren, ACE inhibitors like Captopril and Lisinopril, and angiotensin II receptor blockers such as Losartan and Valsartan. The interaction may affect how these medications control blood pressure.

• Cidofovir and Methotrexate: These drugs may interact adversely, potentially affecting kidney function.

• Corticosteroids (e.g., Prednisone): The combination can increase the risk of side effects.

• Ketoconazole and Levoketoconazole: These antifungals may alter the drug's effects.

• Lithium: This interaction can increase lithium levels, raising the risk of toxicity.

• Diuretics (e.g., Furosemide): These "water pills" can interact and potentially affect kidney function.

This medication may also elevate the risk of bleeding, especially if taken with other drugs that cause bleeding, like anti-platelet drugs (e.g., Clopidogrel) or "blood thinners" (e.g., Dabigatran, Enoxaparin, Warfarin).

Be cautious with over-the-counter medications, particularly those containing pain relievers or fever reducers like Aspirin or NSAIDs (e.g., Celecoxib, Ketorolac, Naproxen), as they are similar to ibuprofen and may increase side effects. If prescribed low-dose aspirin for heart attack or stroke prevention, continue taking it unless advised otherwise by your doctor, as daily ibuprofen use can reduce aspirin's protective effects. Discuss with your doctor about possibly using Acetaminophen for pain or fever instead. If taking both medications, space your ibuprofen and aspirin doses: take this drug at least eight hours before or two hours after aspirin.

Inform your healthcare providers and lab personnel about this medication as it might interfere with certain lab tests, leading to inaccurate results. Always consult your doctor before making any changes to your medication regimen.