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This document outlines crucial safety information for individuals considering the use of Necon 7/7/7, a form of oral contraceptive. It is essential to thoroughly review these warnings and discuss any concerns with your healthcare provider.

• Cardiovascular Risks: Necon 7/7/7 can increase the risk of heart problems and strokes, particularly in women over 35 who smoke. This risk elevates with age, the amount of smoking, high blood pressure, high cholesterol, obesity, and diabetes. Women over 35 who smoke are advised against using this medication.

• Blood Clots: The likelihood of developing blood clots is heightened during the first year of use, or if the medication is restarted after a break of four weeks or more. Risks are elevated post-surgery, during prolonged immobility, or shortly after childbirth. It is advised to cease usage four weeks prior to surgery and for two weeks post-surgery or during bed rest. After childbirth, avoid starting Necon 7/7/7 until four weeks after delivery if not breastfeeding. Be alert for symptoms like sharp chest pain, coughing up blood, shortness of breath, or leg pain, and seek immediate medical attention if these occur.

• Metabolic Effects: This medication may increase blood sugar and cholesterol levels. Individuals with diabetes, prediabetes, or high cholesterol should consult their healthcare provider before starting Necon 7/7/7 and may require regular monitoring.

• Blood Pressure Concerns: Necon 7/7/7 can raise blood pressure, particularly in older individuals or those with prolonged use. Women with significantly high blood pressure should opt for alternative contraceptives. If blood pressure exceeds 160/100 mmHg, consult your provider to consider other birth control options.

• Cancer Risks: There is potential for an increased risk of breast and cervical cancer with the use of Necon 7/7/7, particularly for those with a history of breast cancer or prolonged use of combined oral contraceptives.

• Liver Health: Do not use Necon 7/7/7 if you have liver issues, such as viral liver infection, severe liver scarring, or liver tumors. Discontinue use and consult a provider if you experience symptoms of liver problems, such as jaundice, fever, fatigue, loss of appetite, or dark urine.

Contraindications highlight situations where the use of Necon 7/7/7 could be harmful:

• Blood Disorders: Current or historical blood clots or conditions that increase clotting risk.
• Cardiovascular Issues: History of heart attacks, strokes, or heart valve problems with complications.
• Hypertension: Consistent blood pressure readings over 160/100 mmHg.
• Diabetes Complications: Diabetes accompanied by blood vessel issues.
• Neurological Symptoms: Headaches with nerve complications.
• Post-Surgery: Major surgeries resulting in prolonged immobility.
• Cancer: Current or past breast cancer, uterine cancer, or tumors sensitive to estrogen.
• Unexplained Bleeding: Vaginal bleeding without a diagnosis.
• Liver Concerns: Jaundice during pregnancy or previous medication use, liver problems, or cancer.
• Pregnancy and Drug Interactions: Pregnancy or concurrent use of specific hepatitis C medications.

Always consult with a healthcare provider to ensure this medication is appropriate for your condition and health status.

Common side effects:

• Nausea
• Vomiting
• Stomach cramps
• Bloating
• Bleeding between periods
• Spotting
• Changes in menstrual flow
• Missed periods

Serious side effects:

• Chest pain (heart attack symptom)
• Stomach discomfort (heart attack symptom)
• Sweating (heart attack symptom)
• Nausea (heart attack symptom)
• Dizziness (heart attack symptom)
• Sudden numbness or weakness in the arm, leg, or face (stroke symptom)
• Confusion (stroke symptom)
• Vision problems (stroke symptom)
• Headaches (stroke symptom)
• Difficulty walking (stroke symptom)
• Leg cramps (deep vein thrombosis symptom)
• Swelling (deep vein thrombosis symptom)
• Pain (deep vein thrombosis symptom)
• Muscle tightness (deep vein thrombosis symptom)
• Coughing (pulmonary embolism symptom)
• Chest pain (pulmonary embolism symptom)
• Trouble breathing (pulmonary embolism symptom)
• Racing heart (pulmonary embolism symptom)

When taking Alyacen 7/7/7, it's important to be aware of potential interactions with other medications, herbal products, and certain foods, as these can affect the pill's effectiveness or increase the risk of side effects.

Medications That May Reduce Effectiveness:

Some drugs can decrease the levels of hormones in Alyacen 7/7/7, potentially making it less effective at preventing pregnancy. These include:

• Antibiotics: Certain antibiotics, such as Rifampin and Rifabutin, may reduce the effectiveness of hormonal contraceptives.

• Seizure Medications: Drugs like Phenytoin, Carbamazepine, barbiturates, Topiramate, and Felbamate can lower hormone levels.

• HIV Medications: Some HIV treatments, including nelfinavir and Nevirapine, may interfere with birth control effectiveness.

• Herbal Products: St. John's wort is known to decrease hormone levels in birth control pills.

If you're prescribed any of these, consult your healthcare provider. They may recommend using an additional non-hormonal contraceptive method, like condoms, during and for 28 days after completing the medication to ensure protection against pregnancy.

Medications That May Increase Hormone Levels:

Other substances can raise hormone levels in your body, potentially leading to increased side effects. These include:

• Antifungal Medications: Drugs such as Itraconazole, Ketoconazole, and Fluconazole can elevate hormone concentrations.

• Certain HIV Medications: Medications like Atazanavir and indinavir may increase hormone levels.

• Statins: Cholesterol-lowering drugs like Atorvastatin and Rosuvastatin can affect hormone metabolism.

Food Interactions:

Grapefruit juice can increase the levels of certain hormones in Alyacen 7/7/7, potentially leading to more pronounced side effects. It's advisable to limit or avoid grapefruit juice while taking this medication.

Other Considerations:

Alyacen 7/7/7 may interact with Lamotrigine, a medication used to treat epilepsy, potentially reducing its effectiveness and increasing the risk of seizures. If you're taking lamotrigine, discuss this with your healthcare provider, as dosage adjustments may be necessary.

Additionally, this birth control pill can affect the results of certain laboratory tests, such as those measuring blood clotting factors and thyroid function. Inform your healthcare provider and lab personnel that you're using Alyacen 7/7/7 to ensure accurate test results.

Always inform your healthcare provider about all medications, supplements, and herbal products you're taking to manage potential interactions effectively.