Bunavail Coupons & Savings Card – Discount Prices from $250.54

The following information outlines critical safety warnings associated with the use of Suboxone film (buprenorphine/naloxone). Please read carefully and consult your healthcare provider if you have any questions or concerns.

• Addiction and Misuse Risk: Suboxone is a Schedule III controlled substance due to its inclusion of buprenorphine, which poses a risk for misuse and dependence. Using more than the prescribed dosage can increase the risk of addiction and severe side effects, including dangerously slow breathing and overdose. Individuals with a history of alcohol or substance use disorder should be particularly cautious.

• Respiratory Depression: Buprenorphine in Suboxone can lead to dangerously slow breathing, which may be life-threatening, especially when combined with benzodiazepines, opioids, or alcohol. People over 65, those with chronic obstructive pulmonary disease (COPD), or other conditions that cause slow breathing should exercise caution.

• Opioid Overdose Risk: There is a risk of relapse and overdose in people treated for opioid use disorder. Overdose can occur even at recommended doses and is potentially fatal, particularly in children who accidentally ingest the medication. Those with a history of opioid use disorder or previous overdoses should be aware.

• Impaired Concentration and Sleepiness: Suboxone can cause extreme drowsiness and impair cognitive function. Concurrent use with alcohol or medications such as sedatives can exacerbate these effects. This is especially relevant for individuals over 65.

• Pregnancy Risks: Use of Suboxone during pregnancy can result in the unborn baby becoming dependent on the medication. Pregnant individuals should discuss potential risks with their healthcare provider.

• Adrenal Insufficiency: Long-term use of Suboxone can lead to low adrenal hormone levels, resulting in symptoms like nausea, tiredness, and dizziness. If you experience these symptoms, contact your healthcare provider.

• Withdrawal Symptoms: Long-term use can cause physical dependence, and sudden cessation may lead to withdrawal symptoms, such as anxiety and body aches. Gradual dose reduction is advised.

• Liver Damage: Use of buprenorphine-containing medications can lead to liver damage. Regular liver function tests are recommended, especially for those with a history of liver damage, hepatitis B or C, or injection drug use.

• Dental Health Issues: Some users have experienced dental problems, including cavities and tooth loss, due to the medication dissolving in the mouth.

• Heart Rhythm Abnormalities (QT Prolongation): Buprenorphine can cause QT prolongation, potentially leading to severe heart rhythm issues. Those with existing heart conditions should be cautious.

• Low Blood Pressure: Suboxone may cause a significant drop in blood pressure, leading to dizziness or fainting. Standing up slowly from a sitting or lying position can help minimize these effects.

• Not Suitable for Pain Management or Opioid-Naïve Individuals: Suboxone is not intended for pain relief or individuals who have never taken opioids, as fatal overdoses have occurred under these circumstances.

Contraindications: Suboxone should not be used by individuals with a severe allergy to buprenorphine or naloxone. If applicable, discuss alternatives with your healthcare provider.

When taking Bunavail, it's important to be aware of potential interactions with other substances, as these can affect how the medication works and may lead to serious side effects. Here are some key interactions to consider:

Central Nervous System (CNS) Depressants: Combining Bunavail with other CNS depressants, such as benzodiazepines (e.g., Diazepam, Alprazolam), sedatives, muscle relaxants, or alcohol, can enhance sedative effects. This may result in profound drowsiness, respiratory depression, coma, or even death. It's crucial to avoid using these substances together unless specifically directed by a healthcare provider.

Certain Medications: Some drugs can alter the effectiveness of Bunavail by affecting how it's metabolized in the body. For instance:

• CYP3A4 Inhibitors: Medications like certain antibiotics (e.g., Erythromycin), antifungals (e.g., Ketoconazole), and HIV protease inhibitors (e.g., Ritonavir) can increase Bunavail levels, potentially leading to enhanced effects or side effects. Monitoring and possible dose adjustments may be necessary when these are used concurrently.

• CYP3A4 Inducers: Drugs such as Rifampin, Carbamazepine, and Phenytoin can decrease Bunavail levels, possibly reducing its effectiveness. Your doctor may need to adjust your Bunavail dose if you're taking these medications.

Serotonergic Drugs: Using Bunavail alongside medications that affect serotonin levels, like certain antidepressants (e.g., SSRIs, SNRIs), can increase the risk of serotonin syndrome—a potentially life-threatening condition. Symptoms include agitation, hallucinations, rapid heartbeat, and high blood pressure. Immediate medical attention is required if these occur.

Herbal Supplements: Some herbal products, such as St. John's Wort, can interact with Bunavail, potentially altering its effectiveness. Always inform your healthcare provider about any supplements you're taking.

Alcohol: Consuming alcohol while on Bunavail can intensify CNS depressant effects, leading to dangerous side effects like respiratory depression and loss of consciousness. It's advisable to avoid alcohol during treatment.

Other Medications: Certain drugs, including antihistamines (e.g., diphenhydramine), antipsychotics, and specific antibiotics, may interact with Bunavail. These interactions can lead to increased side effects or reduced effectiveness of the medications involved.

Always inform your healthcare provider about all medications, supplements, and substances you're using to ensure safe and effective treatment with Bunavail.