Deferasirox Coupons & Discount Card – Guaranteed Prices from $333.97

Deferasirox is associated with several serious potential risks that require careful consideration and monitoring. Below are important safety warnings and precautions to be aware of when using this medication:

• Kidney Risks: Deferasirox may lead to severe kidney problems, which could be life-threatening and require dialysis. This risk is heightened in individuals with pre-existing kidney conditions, serious blood diseases, or those taking other medications affecting the kidneys, such as young children or dehydrated children. Regular kidney function monitoring is essential.

• Liver Risks: This medication can cause severe liver complications, particularly in older adults, individuals with cirrhosis or organ failure, and dehydrated children. Liver function should be closely monitored, especially if there is a history of liver issues or serious medical conditions.

• Gastrointestinal Bleeding: The medication may cause stomach bleeding and ulcers, especially in older adults with severe blood disorders. Certain drugs, like NSAIDs, corticosteroids, bisphosphonates, and blood thinners, can increase this risk. Immediate medical attention is necessary if there are symptoms such as severe stomach pain, black stools, or blood in the urine.

• Blood Cell Reduction: Deferasirox can reduce blood cell counts, posing significant risks to those with existing blood disorders. Regular blood tests will be conducted to monitor this, and any signs of bleeding or infections should be reported to a healthcare provider.

• Excessive Iron Removal: In some cases, deferasirox may cause too much iron to be removed, harming the kidneys and liver. Patients undergoing blood transfusions or with non-transfusion-dependent thalassemia (NTDT) will have their iron levels checked regularly to ensure safe dosing.

• Skin Reactions: Rash or severe skin reactions may occur. If mild, continue the medication and inform your provider. Severe reactions, such as blistering or skin pain, require immediate medical attention and may necessitate pausing the medication.

• Vision and Hearing Concerns: Vision and hearing issues can arise, particularly in children on higher doses. Eye and hearing examinations are recommended before starting treatment and annually thereafter. Any changes in vision or hearing should be promptly discussed with a healthcare provider.

Contraindications:

Deferasirox should not be used in the following conditions due to significant health risks:

• Moderate or severe kidney disease.
• High-risk myelodysplastic syndromes.
• Aggressive tumors or advanced blood cancers.
• Severely low platelet counts.
• Poor performance status, such as an inability to care for oneself.

In case of an overdose, immediate medical attention is necessary. Regular follow-ups and adherence to prescribed dosages are crucial to minimize risks and ensure safe treatment with deferasirox. Always consult with a healthcare provider for personalized guidance and report any concerning symptoms or side effects.

Common side effects:

• Diarrhea
• Stomach pain
• Nausea
• Vomiting
• Skin rash

Less common but important to monitor:

• Dizziness
• Anxiety
• Sleep problems
• Changes in skin color
• Alterations in vision or hearing

Serious side effects:

• Sudden kidney injury
• Liver damage
• Stomach bleeding
• Low blood cell counts
• Severe skin reactions
• Serious allergic reaction

Interactions with high risk of serious adverse effects and should be avoided:

• Fezolinetant
• Aspirin
• Antiplatelet drugs such as Clopidogrel
• NSAIDs such as Ibuprofen/Naproxen
• Blood thinners such as Dabigatran/Warfarin

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Tovorafenib
• Hormonal birth control methods (e.g., pills, patches, rings)
• Aluminum-based compounds
• Amiodarone
• Busulfan
• Cholestyramine
• Colesevelam
• Colestipol
• Duloxetine
• Enzalutamide
• Fosphenytoin
• Pexidartinib
• Phenobarbital
• Phenytoin
• Rifampin
• Ritonavir
• Selexipag
• Theophylline
• Tizanidine
• Tucatinib
• Warfarin

Interactions with low risk that usually do not require a change in therapy:

• Repaglinide