Weight LossOpioid Antagonist / Atypical Antidepressant CombinationsContrave coupons
Contrave

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This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life. Naltrexone belongs to a class of drugs known as opiate antagonists. Bupropion is an antidepressant that helps to restore the balance of certain natural substances (dopamine, norepinephrine) in the brain. These two medications work together on separate parts of the brain to reduce appetite and how much you eat. Most opiates should not be used for 7 to 10 days before starting naltrexone, but some opiate drugs (such as methadone) should not be used for 10 to 14 days before starting naltrexone. Ask your doctor or pharmacist for more details. Other forms of naltrexone or bupropion are used to treat a variety of conditions including depression, other mental/mood disorders, smoking cessation, addiction to opioid medication, and alcohol abuse. This combination product is not approved for these other uses. Discuss the risks and benefits of this medication, as well as other ways to lose weight, with your doctor.
Our Contrave coupons are free to use. You can print the coupon, email it to yourself, or receive the Contrave coupon via text message. To get your free discount, show the pharmacist your Contrave savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Contrave prices will update based on your prescription needs. Above our Contrave coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Contrave savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.
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8-90MG, Contrave (30 Tablet Extended Release 12 Hours)

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CVS

$146.37

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Warnings

This medication is a combination of bupropion and naltrexone. Bupropion is an antidepressant used to treat a variety of conditions, including depression and other mental/mood disorders. It can also be prescribed to help with smoking cessation or weight loss. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. However, studies have shown that a small number of people (especially people younger than 25) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. It is very important to talk with the doctor about the risks and benefits of antidepressant medication (especially for people younger than 25), even if treatment is not for a mental/mood condition. Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed. If you are using naltrexone/bupropion to lose weight, stop taking this medication and tell your doctor right away if you have any of the symptoms listed above. Tell your doctor right away if you have any of these symptoms after stopping treatment.

Contrave Side Effects

See also Warning, How to Use, and Precautions sections. Nausea, vomiting, constipation, stomach pain, headache, dizziness, trouble sleeping, increased sweating, flushing, and dry mouth or strange taste in the mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (anxiety, agitation, confusion, memory loss), uncontrolled movements (tremor), ringing in the ears, fainting, severe headache, fast/pounding/irregular heartbeat, chest pain. Get medical help right away if you have any very serious side effects, including: eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbow around lights at night). If you have been taking opioid medications regularly, you could have withdrawal symptoms within minutes after taking naltrexone. Tell your doctor right away if you have any of the following symptoms of opioid withdrawal: mental/mood changes (such as anxiety/irritability), fast breathing, yawning, sweating, watering eyes, goose bumps, muscle twitching. This drug may rarely cause seizures. Get medical help right away if you have a seizure. If you have a seizure while taking bupropion, you should not take this drug again. Naltrexone may rarely cause serious (possibly fatal) liver disease. The risk is increased when larger doses are used. Discuss the risks and benefits with your doctor. Stop using this medication and tell your doctor right away if you have symptoms of liver damage, including: nausea/vomiting that doesn't stop, loss of appetite, severe stomach/abdominal pain, yellowing eyes/skin, dark urine. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: dextromethorphan, diarrhea medications (such as diphenoxylate), disulfiram, pimozide, opioid pain or cough relievers (such as codeine, hydrocodone), tamoxifen, thioridazine. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication. This medication may interfere with certain medical/lab tests (such as urine tests for amphetamine, opioid drug tests, and brain scan for Parkinson's disease), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Contrave FAQs
What does Contrave do for weight loss?

Contrave is a prescription medication that combines two drugs, bupropion and naltrexone, to aid in weight loss. It works by affecting the central nervous system to help reduce appetite and control cravings. This medication is typically used in conjunction with a reduced-calorie diet and increased physical activity for adults who are obese or overweight with weight-related medical problems.

Contrave and Ozempic are not the same. Contrave is a combination medication containing bupropion and naltrexone, primarily used for weight management. Ozempic, on the other hand, is a medication containing semaglutide, used to improve blood sugar control in adults with type 2 diabetes and also for weight management. They have different active ingredients and mechanisms of action.

Contrave and Wellbutrin are not the same, although they both contain bupropion. Contrave is a combination medication that includes bupropion and naltrexone, and it is used for weight management. Wellbutrin, on the other hand, contains only bupropion and is primarily used as an antidepressant and for smoking cessation.

Contrave, a medication used for weight management, may have several potential downsides or side effects. Common side effects include nausea, constipation, headache, vomiting, dizziness, insomnia, and dry mouth. More serious side effects can include increased blood pressure, increased heart rate, liver damage, seizures, and potential for suicidal thoughts or behaviors. It is important for individuals to discuss their medical history and any potential risks with their healthcare provider before starting Contrave.

An alternative to Ozempic, which is a GLP-1 receptor agonist used for managing type 2 diabetes, could be other medications within the same class. These include drugs like Trulicity (dulaglutide), Victoza (liraglutide), and Bydureon (exenatide extended-release). The choice of an alternative should be based on individual patient needs, medical history, and a healthcare provider's recommendation.

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