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Medroxyprogesterone

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medroxyprogesterone

Medroxyprogesterone acetate, also known as Depo-Provera or Depo-SubQ Provera, is a progestin-only contraceptive used to prevent pregnancy. It is administered by a healthcare professional through an injection into the muscle or under the skin every three months. In addition to birth control, it is specifically used to manage pain associated with endometriosis, particularly with the Depo-SubQ Provera 104 formulation. The medication functions by halting ovulation, which is the release of an egg from the ovaries, and by preventing any fertilized egg from attaching to the uterine wall. For endometriosis-related pain, it works by thinning the uterine lining. It is important to note that Medroxyprogesterone does not provide protection against sexually transmitted infections, including HIV, gonorrhea, and chlamydia. Common side effects may include alterations in menstrual cycles, headaches, and weight gain. Long-term use can lead to bone density reduction, thus its use is generally limited to a period of two years unless otherwise advised by a healthcare provider. Always consult with a healthcare professional for personalized medical advice.
Our Depo-provera coupons are free to use. You can print the coupon, email it to yourself, or receive the Depo-provera coupon via text message. To get your free discount, show the pharmacist your Depo-provera savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Depo-provera prices will update based on your prescription needs. Above our Depo-provera coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Depo-provera savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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1ML of 150MG/ML, Medroxyprogesterone (1 Vial)

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CVS

$28.20

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Walgreens

$23.44

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Rite Aid

$26.64

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$29.87

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Depo-provera savings card

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CVS

$28.20

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Depo-provera dosage forms

The average cost for 1 Vial of Depo-provera (medroxyprogesterone) at 1ML of 150MG/ML is $23.44 with a free coupon. This is 43.41% off the average retail price of $54
DosageQuantityPrice fromPer unit
1ML of 150MG/ML1 Vial$23.44$23.44

Depo-provera Warnings

When considering the use of medroxyprogesterone (Depo-Provera), it is essential to be aware of certain safety warnings and precautions. This information outlines potential risks, recommended precautions, and instructions for specific populations. Please discuss any concerns with your healthcare provider to ensure this medication is appropriate for you.

  • Bone Health: Use of medroxyprogesterone can lead to calcium loss in bones, increasing the risk of osteoporosis and fractures. This risk is higher with long-term use, especially beyond two years, and in individuals who smoke or have a history of anorexia nervosa, prolonged corticosteroid use, or a family history of osteoporosis.

  • Blood Clots: There is a potential risk of developing blood clots while using this medication. If you have a personal history of blood clots, this medication may not be suitable. Seek immediate medical attention if you experience symptoms such as leg pain, chest pain, severe headaches, or difficulties in breathing.

  • Breast Cancer Risk: Those with a personal or family history of breast cancer should avoid using medroxyprogesterone, as it may stimulate hormone-sensitive cancers. Monthly breast self-exams are advised, and any changes should be reported to your healthcare provider.

  • Ectopic Pregnancy: Although rare, the risk of ectopic pregnancy exists. Notify your provider if you experience severe pelvic pain or unusual vaginal bleeding, especially if you become pregnant within three months of your last dose.

  • Menstrual Changes: This medication can cause changes in menstrual cycles, leading to light, heavy, or absent periods. Consult your provider if you experience excessively heavy bleeding.

  • Allergic Reactions: Severe allergic reactions, including anaphylaxis, are possible. If you experience symptoms such as hives, swelling, or difficulty breathing, seek emergency medical help immediately.

  • Weight Changes: Weight gain is a reported side effect, with an average increase of 5 pounds in one year and up to 17 pounds over six years. Discuss any concerns about weight with your healthcare provider.

  • Fertility Post-Medication: Fertility may take time to return after stopping medroxyprogesterone, with some individuals taking two years or more to conceive. Consider this if planning for pregnancy in the future.

  • Seizure Risk: Seizures have been reported in some users. If you have a history of seizures, discuss this with your provider before starting the medication.

  • Liver Health: Report symptoms suggestive of liver problems, such as stomach pain, yellowing of the skin or eyes, or clay-colored stools, to your provider immediately for assessment and potential discontinuation of the medication.

Contraindications:

  • Do not use medroxyprogesterone if you are pregnant or suspect pregnancy, have a history of blood clots, known or suspected breast cancer, serious liver issues, or unexplained vaginal bleeding. Always consult your healthcare provider to ensure this medication is safe for your health condition.

Depo-provera Side Effects

When taking this medication, some common side effects may include nausea, bloating, headache, changes in appetite, weight gain, tiredness, swelling, acne, hot flashes, breast tenderness, and irritation or pain at the injection site. You might also experience changes in your menstrual cycle, such as no menstrual period, irregular periods, or spotting, particularly in the initial months of use. These effects are generally mild, but if they persist or worsen, consult your healthcare provider.

In some cases, more serious side effects can occur, necessitating immediate medical attention. These include persistent nausea or vomiting, mental or mood changes like depression, changes in sexual interest or ability, swelling of the ankles or feet, bone pain, unusual changes in vaginal bleeding, severe abdominal or pelvic pain, unusual tiredness, dark urine, and yellowing of the eyes or skin. Be vigilant for symptoms that may suggest blood clots, such as sudden shortness of breath, chest pain, unusual sweating, confusion, sudden dizziness or fainting, pain or swelling in the groin or calf, severe headaches, trouble speaking, weakness on one side of the body, or sudden vision changes.

It's important to be aware of a rare but serious risk of blood clots, which can lead to heart attack, stroke, or clots in the lungs, legs, or eyes. Additionally, your risk of breast cancer may increase; look out for symptoms like a lump in the breast or unusual nipple discharge and seek medical advice promptly. Although severe allergic reactions are rare, seek urgent care if you experience symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing.

Always report any side effects to your healthcare provider, as they can provide guidance and support tailored to your specific situation.

Depo-provera Interactions

Certain medications may reduce the effectiveness of hormonal birth control, potentially leading to unintended pregnancy. These include drugs like griseofulvin, Modafinil, various rifamycins (such as Rifampin and Rifabutin), Ritonavir, St. John's Wort, and medications for seizures (such as barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, and Topiramate). Some HIV medications, including nelfinavir and Nevirapine, can also have this effect. If you begin taking any new medication, inform your doctor to discuss the need for additional birth control methods. Spotting or breakthrough bleeding may indicate reduced birth control efficacy, so report these symptoms to your doctor.

Medroxyprogesterone (Depo-Provera) can interact with various medications and supplements. It is crucial to inform your healthcare provider and pharmacist about all the medications and supplements you are using, including prescription, over-the-counter, vitamins, and herbal products. Tranexamic Acid should not be used with Medroxyprogesterone. In some cases, combining Medroxyprogesterone with other medications like apalutamide, Armodafinil, carbamazepine, and several others (including some anti-epileptics, HIV medications, and herbal supplements like St. John's Wort) may require dosage adjustments or careful monitoring. Always consult your doctor when managing your medication regimen.

Depo-provera FAQs
What is a bad side effect of Depo?

A notable side effect of Depo-Provera (medroxyprogesterone acetate) is a potential decrease in bone mineral density, which can increase the risk of osteoporosis and fractures over time. Other side effects may include weight gain, changes in menstrual cycles, and mood changes. It is important for individuals to discuss these potential risks with their healthcare provider.

The signs of Depo-Provera wearing off can include the return of menstrual periods, which may initially be irregular. Some individuals might experience symptoms such as changes in mood, weight fluctuations, or a return of premenstrual symptoms. Fertility may gradually return, but it can take some time for ovulation to resume. If there are concerns about specific symptoms or the timing of fertility return, consulting a healthcare provider is recommended.

Depo-Provera, a form of birth control, can lead to weight gain in some individuals, which may include an increase in belly fat. However, weight changes can vary from person to person, and not everyone will experience this side effect. It's important to discuss any concerns about weight gain with a healthcare provider, who can provide personalized advice and guidance.

The disadvantages of the Depo-Provera shot, a form of birth control, may include the following:1. Irregular Menstrual Bleeding: Users may experience changes in their menstrual cycle, including irregular bleeding or spotting, especially in the first few months.2. Weight Gain: Some individuals may experience weight gain while using the Depo shot.3. Bone Density Loss: Long-term use can lead to a decrease in bone mineral density, which may increase the risk of osteoporosis.4. Delayed Fertility Return: After stopping the shot, it may take some time for fertility to return to normal, sometimes up to 10 months or more.5. Mood Changes: Some users report mood swings or depression.6. Other Side Effects: These can include headaches, breast tenderness, and changes in libido.It is important for individuals to discuss these potential disadvantages with their healthcare provider to determine if the Depo shot is the right contraceptive method for them.

The Depo-Provera shot, a form of birth control, is generally considered safe and effective for many individuals. However, like any medication, it may have side effects and risks. Some people may experience changes in menstrual cycles, weight gain, or decreased bone density with long-term use. It is important for individuals to discuss their medical history and any concerns with their healthcare provider to determine if the Depo shot is a suitable option for them.