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Using Low-Ogestrel, a combined oral contraceptive, comes with important safety considerations. Carefully review the following information and consult with your healthcare provider if you have any questions or concerns.

• Smoking and Cardiovascular Risks: Avoid using this medication if you smoke cigarettes and are over 35 years old, as it significantly increases the risk of stroke, heart attack, and blood clots. Smoking, especially in older individuals, heightens these risks. Discuss safer birth control options with your healthcare provider if you smoke.

• Blood Clots and Strokes: Low-Ogestrel can elevate the risk of blood clots, which may manifest in the lungs, legs, brain, or heart. Immediate medical attention is needed if you show any signs of blood clots, especially if you are over 35 and smoke, have undergone recent surgery, started the medication shortly after childbirth, or have pre-existing conditions like high blood pressure, obesity, high cholesterol, or diabetes.

• Cancer Risks: There is a potential increase in the risk of breast and cervical cancer with prolonged use of Low-Ogestrel. This is particularly concerning for individuals with a history of breast cancer.

• Liver Complications: Although rare, Low-Ogestrel may cause liver issues such as liver damage or tumors. Do not use this medication if you have existing liver problems. Contact your healthcare provider immediately if you experience symptoms like fatigue, abdominal pain, or jaundice.

• Blood Sugar and Triglycerides: This contraceptive may raise blood sugar and triglyceride levels, which is particularly important for those with diabetes or a family history of high triglycerides. Regular monitoring by your healthcare team is recommended.

• High Blood Pressure: Low-Ogestrel can cause increased blood pressure. Regular monitoring is advised, and if you have uncontrolled high blood pressure, consider alternative contraceptives.

• Headaches and Migraines: Common side effects include headaches. Seek medical advice if you experience new, worsening, or severe migraines.

• Irregular Bleeding: Breakthrough bleeding or spotting may occur, especially within the first three months. Inform your healthcare provider if irregular bleeding persists.

• Depression: Monitor for signs of depression or worsening symptoms while using Low-Ogestrel. Discuss with your healthcare provider if you have a history of depression.

• Gallbladder Issues: There may be an increased risk of gallbladder disease, especially for individuals with a history of such conditions.

• Drug Interactions: Certain medications can impact the effectiveness of Low-Ogestrel, increasing the risk of pregnancy or side effects. Inform your healthcare provider of all medications you are taking to prevent interactions.

Contraindications: Do not use Low-Ogestrel if you have a history of blood clotting disorders, cardiovascular diseases, certain types of migraines, uncontrolled high blood pressure, hormone-sensitive cancers, liver disease, or are pregnant. Also, avoid use if taking specific hepatitis C medications.

Always consult with a healthcare professional for tailored advice and to ensure safe use of Low-Ogestrel, especially if you have existing health conditions or are taking other medications.

When using this medication, some common side effects may include nausea, vomiting, headaches, bloating, and breast tenderness. You might also experience swelling in the ankles or feet due to fluid retention, and changes in weight. It is not unusual to have vaginal bleeding between periods or to miss periods, especially during the first few months. If these side effects persist or worsen, it is important to consult with your healthcare provider. Additionally, this medication can potentially increase blood pressure, so regular monitoring is advised.

Some individuals may notice mood changes, such as depression or nervousness, as well as physical symptoms like back pain, acne, or changes in appetite. Fatigue, darker skin patches, and aggravated varicose veins are also possible. While these are generally mild, seeking medical advice if they become bothersome is recommended.

There are serious side effects that, although rare, require immediate medical attention. These include symptoms indicative of a heart attack (chest pain, nausea, dizziness), stroke (sudden numbness, confusion, headache), deep vein thrombosis (leg pain, swelling), and pulmonary embolism (chest pain, trouble breathing). Serious liver issues may present as yellowing of the skin or eyes and require urgent care.

In rare cases, allergic reactions can occur, characterized by rash, itching, or swelling of the face, tongue, or throat. If you experience severe dizziness or trouble breathing, seek emergency medical help. Always report any unusual or severe side effects to your healthcare provider promptly.

Certain medications can interact with this drug, potentially altering its effectiveness. These include aromatase inhibitors like anastrozole and exemestane, fezolinetant, ospemifene, tamoxifen, tizanidine, and tranexamic acid. Additionally, some medications might reduce the effectiveness of hormonal birth control by lowering hormone levels, which could lead to an unintended pregnancy. Such medications include griseofulvin, modafinil, certain antibiotics like rifampin and rifabutin, ritonavir, herbal supplements like St. John's wort, and drugs used for seizures, such as barbiturates, carbamazepine, felbamate, phenytoin, primidone, and topiramate, as well as HIV treatments like nelfinavir and nevirapine.

It's important to inform your doctor of any new medications you start and consider using an additional form of birth control if necessary. If you notice unusual spotting or bleeding, contact your doctor, as these may indicate that your birth control is not fully effective. Be aware that this medication can also affect the results of certain lab tests, such as those measuring blood clotting factors and thyroid function, so ensure that all healthcare providers are informed that you are taking this drug.