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This medication requires careful consideration due to several safety risks and warnings. It is crucial to be aware of these potential issues and discuss any concerns with your healthcare provider. Below are key safety details:

• Pregnancy Risk: This medication can cause significant harm, potentially fatal, to an unborn baby. It is imperative to avoid pregnancy while using this drug. If you become pregnant, suspect pregnancy, or are planning to become pregnant, immediately consult your doctor to explore safer treatment alternatives.

• Angioedema Warning: Use of this medication can result in angioedema, a rare but severe swelling that can affect the face, throat, and tongue, potentially obstructing breathing. This risk is greater in Black individuals. If you experience any swelling, stomach pain, or breathing difficulties, seek immediate medical attention and discontinue the medication.

• Low Blood Pressure Alert: The drug might cause your blood pressure to drop excessively, leading to dizziness, tiredness, or lightheadedness, especially when starting or increasing the dose. Stay hydrated, and if you feel faint or dizzy, sit down carefully and contact your healthcare team. Immediate medical help is necessary if you fall and hit your head.

• Kidney Health Monitoring: This medication can impair kidney function, especially in those with existing kidney issues or severe heart failure. Regular kidney function tests may be required. Inform your doctor if you notice a decrease in urination.

• Liver Complications: In rare cases, this drug can cause liver problems or liver failure. Blood tests to monitor liver health might be performed. Report symptoms like fatigue, stomach pain, or yellowing of the skin to your healthcare provider promptly.

• Electrolyte and Metabolic Changes: The medication can alter electrolyte, blood sugar, and cholesterol levels. Regular blood tests may be needed. Notify your doctor if you experience a rapid heartbeat, weakness, or muscle pain, as these may signal electrolyte imbalances.

• Vision Issues: Rarely, this drug can lead to vision changes. Report any such changes or eye pain immediately. In some instances, surgery might be necessary to prevent permanent vision loss.

• Lupus Symptoms: The medication may rarely exacerbate or induce lupus. Notify your doctor if you observe a rash across the cheeks and nose or feel excessively tired.

Contraindications:

• Do not use this medication if you have diabetes and are taking aliskiren (Tekturna).
• Avoid if you are using neprilysin inhibitors like Entresto (sacubitril/valsartan) within 36 hours.
• Contraindicated for those not producing urine, or with allergies to sulfa medications or ACE inhibitors.
• Not suitable for individuals with a history of severe swelling (angioedema).

Always consult your healthcare provider for personalized advice and before making any changes to your medication regimen.

When taking this medication, you might experience some common side effects as your body adjusts. These can include dizziness, tiredness, headaches, or a persistent dry cough. It's also possible to feel lightheaded, particularly when standing up too quickly, or experience blurred vision. While these effects are generally mild, if they continue or worsen, it's advisable to consult your healthcare provider for guidance.

There are other side effects that, though less common, may occur such as nausea, drowsiness, or a sensation of spinning. Some individuals might also encounter difficulties with maintaining an erection. If these symptoms become severe or troubling, seeking medical advice is recommended.

Serious side effects, though rare, demand immediate medical attention. Such symptoms include severe allergic reactions like angioedema, characterized by swelling of the face, lips, tongue, or throat, and trouble breathing. Additionally, any signs of dangerously low blood pressure, such as feeling faint or having pale skin, should be addressed urgently. Kidney issues might manifest as reduced urination or swelling in the extremities, while liver problems could present as yellowing of the skin or eyes, abdominal pain, or persistent nausea and vomiting. Always remain vigilant and seek prompt medical care if any severe side effects arise.

When taking Lotensin HCT, which contains benazepril and hydrochlorothiazide, it's important to be aware of potential interactions with other medications. Inform your healthcare provider about all medicines and supplements you are currently using, including over-the-counter drugs, vitamins, and herbal supplements.

Some medications should not be used together with Lotensin HCT, such as aliskiren, dofetilide, and sacubitril, as they can cause significant interactions. Others, like aceclofenac, losartan, and lithium, might be used together only if absolutely necessary, in which case your doctor may adjust their dosages.

Additionally, using Lotensin HCT alongside medications or supplements that raise potassium levels, such as certain ARBs (e.g., losartan or valsartan) and birth control pills containing drospirenone, can pose risks. Also, caution is advised with drugs that may affect your immune system, such as everolimus and sirolimus, as well as gold injections and probenecid.

Moreover, if you are receiving injections for bee or wasp sting allergies, taking Lotensin HCT can lead to a severe reaction. Always ensure that all your healthcare providers are aware of your complete medication list to manage these risks effectively.

Finally, some products, especially cough-and-cold medications, diet aids, and NSAIDs (e.g., ibuprofen and naproxen), may increase your blood pressure or worsen heart failure, so consult your pharmacist on how to use them safely.