Promethazine-phenyleph-codeine Coupons & Discount Card - Compare Prices Near You
generic Promethazine Vc/codeine
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118ML of 6.25-5-10MG/5ML, Promethazine-phenyleph-codeine (1 Bottle)
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CVS
$61.61
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Walgreens
$11.83
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Rite Aid
$23.39
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Albertsons
$25.19
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Walmart
$53.79
COUPON PRICEPromethazine-phenyleph-codeine savings card
Show this card to your pharmacistCVS
$61.61
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019876
LHD4A9D79D
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Promethazine-phenyleph-codeine dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 118ML of 6.25-5-10MG/5ML | 1 Bottle | $11.83 | $11.83 |
Promethazine-phenyleph-codeine Warnings
This medication carries a potential for abuse and addiction, which may result in overdose and even death. It is important to be aware that this medication can also lead to severe, potentially fatal, breathing issues. To minimize these risks, your healthcare provider should prescribe the smallest effective dose for the shortest duration necessary.
- The likelihood of experiencing severe breathing problems is elevated when initiating this treatment, or if you take the incorrect dose or consume more than prescribed.
- Combining this medication with alcohol or other substances that induce drowsiness or respiratory depression can lead to serious, life-threatening side effects.
- Certain medications may interfere with the elimination of this drug from your system, affecting its efficacy. Ensure you understand how to take this medication and know which drugs to avoid in conjunction with it.
Seek immediate medical attention if you experience symptoms such as slow or shallow breathing, unusual lightheadedness, severe drowsiness or dizziness, or difficulty waking up. Store this medication safely to prevent theft, misuse, or abuse. If someone accidentally ingests this drug, obtain medical help immediately.
Women of childbearing age should consult their healthcare provider about the risks and benefits before using this medication. If you are pregnant or suspect you might be, inform your doctor, as this medication is not recommended during pregnancy. It may slightly increase the risk of birth defects in the first two months of pregnancy and can harm the unborn baby if used long-term or in high doses near the expected delivery date. To reduce these risks, use the smallest effective dose for the shortest time possible. Newborns exposed to this drug for an extended period may experience severe, potentially fatal withdrawal symptoms. Contact your doctor immediately if you notice symptoms in your newborn such as persistent crying, slow or shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight.
Promethazine-phenyleph-codeine Side Effects
Common side effects:
- Drowsiness
- Dizziness
- Headache
- Lightheadedness
- Blurred vision
- Upset stomach
- Nausea
- Nervousness
- Trouble sleeping
- Constipation
- Dry mouth
Serious side effects:
- Sleep apnea
- Involuntary movements
- Changes in mood or mental state
- Ringing in the ears
- Tremors
- Difficulty urinating
- Weakness
- Persistent nausea or vomiting
- Chest pain
- Easy bruising or bleeding
- Slow heartbeat
- Severe abdominal pain
- Yellowing of the skin or eyes
- Shallow breathing
- Extreme drowsiness
- Confusion
- Neuroleptic malignant syndrome (NMS)
- Allergic reactions
Promethazine-phenyleph-codeine Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine)
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Other opioid pain or cough medications (morphine, hydrocodone)
- Alcohol
- Marijuana (cannabis)
- Drugs for sleep or anxiety (alprazolam, lorazepam, zolpidem)
- Muscle relaxants (carisoprodol, cyclobenzaprine)
- Other antihistamines (cetirizine, diphenhydramine)
- Azole antifungals (ketoconazole)
- Bupropion
- Fluoxetine
- Macrolide antibiotics (erythromycin)
- Paroxetine
- Quinidine
- Rifamycins (rifabutin, rifampin)
- Ritonavir
- Seizure medications (carbamazepine, phenytoin)
Interactions with low risk that usually do not require a change in therapy:
- Antihistamines applied to the skin (diphenhydramine cream, ointment, spray)
- Cimetidine
- Metoclopramide
- Naltrexone
- Samidorphan
Why did they discontinue promethazine with codeine?
Promethazine with codeine was discontinued in some areas due to concerns about misuse, abuse, and the potential for addiction. The combination of an opioid (codeine) and an antihistamine (promethazine) can lead to serious side effects, including respiratory depression, especially in children. Regulatory agencies have taken steps to limit its availability to reduce the risk of these adverse effects and to address the opioid crisis.
What is the difference between codeine phosphate and promethazine?
Codeine phosphate and promethazine are two different medications with distinct uses. Codeine phosphate is an opioid used primarily for its analgesic (pain-relieving) and antitussive (cough-suppressing) properties. Promethazine, on the other hand, is an antihistamine used to treat allergy symptoms, nausea, and motion sickness, and it also has sedative properties. While they can sometimes be combined in certain formulations to treat specific conditions, they serve different primary purposes.
Why is promethazine a high risk medication?
Promethazine is considered a high-risk medication due to its potential for causing significant side effects and adverse reactions. These can include severe respiratory depression, especially in children under two years of age, and sedation, which can impair cognitive and motor functions. Additionally, promethazine can cause severe tissue injury if administered improperly, such as through intravenous injection. It also has the potential for misuse and can interact with other medications, leading to increased risk of complications. Therefore, it requires careful monitoring and consideration when prescribed.
What is stronger than codeine phosphate?
Medications that are generally considered stronger than codeine phosphate include hydrocodone, oxycodone, and morphine. These opioids are typically used for managing more severe pain and are prescribed based on the specific needs and medical condition of the patient. It is important for a healthcare provider to determine the most appropriate medication and dosage.
Who should avoid promethazine?
Individuals who should avoid promethazine include those with a known allergy to promethazine or any of its components. It should also be avoided by individuals with certain medical conditions such as severe respiratory depression, asthma, or sleep apnea. Additionally, it is not recommended for use in children under two years of age due to the risk of severe respiratory depression. Pregnant or breastfeeding women should consult their healthcare provider before using promethazine. It is also important for individuals with a history of seizures, cardiovascular disease, or liver problems to discuss the use of promethazine with their healthcare provider.