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You might experience some mild side effects like drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or a dry mouth, nose, or throat. These effects are usually temporary, but if they persist or worsen, it's important to seek advice from a healthcare professional. To ease dry mouth, consider using sugarless gum, candies, or ice chips, and stay well-hydrated. This medication can sometimes thicken mucus in the lungs, making breathing more challenging, so drinking plenty of fluids can help, unless advised otherwise.

To minimize dizziness or lightheadedness, rise slowly from sitting or lying positions. Serious side effects are less common, but be vigilant for symptoms like mental or mood changes, ringing in the ears, tremors, difficulty urinating, unexplained weakness, easy bruising or bleeding, or irregular heartbeat. These require immediate medical attention.

Although rare, severe allergic reactions can occur. Seek emergency help if you experience symptoms such as a rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing. This list does not include all possible side effects, so consult a healthcare provider if you notice other unusual symptoms.

Some MAO inhibitors can lead to a severe and potentially life-threatening reaction when combined with this medication. Do not use isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine while taking this medication. Additionally, most MAO inhibitors should not be used for two weeks before and after your treatment with this medication. Consult your doctor for guidance on when to begin or discontinue this medication.

Certain products might interact with this medication, including skin-applied antihistamines (like diphenhydramine cream, ointment, or spray) and rolapitant. Inform your doctor or pharmacist if you are using other substances that cause drowsiness, such as opioid pain or cough medications (like codeine or hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety medications (like alprazolam, lorazepam, or zolpidem), muscle relaxants (like carisoprodol or cyclobenzaprine), or other antihistamines (such as cetirizine or diphenhydramine).

Review the labels on all your medications, including allergy or cough-and-cold products, as they may contain ingredients that cause drowsiness. Your pharmacist can provide advice on safe usage.

This medication could affect certain medical or laboratory tests (such as brain scans for Parkinson's disease, urine drug screening tests, and allergy skin tests), potentially leading to inaccurate results. Ensure that all lab personnel and healthcare providers are aware that you are using this medication.