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Please take a moment to review the following important safety information regarding the use of this medication. It is essential to understand these risks and precautions to ensure safe usage. Consult your healthcare provider if you have any questions or concerns.

• Risk of Addiction and Misuse: Oxycodone is a controlled substance with a potential for addiction and misuse. Use it strictly as prescribed. Do not alter the dosage or frequency without consulting your healthcare provider. Individuals with a personal or family history of substance use disorder or mental health issues may be at higher risk.

• Respiratory Depression: Oxycodone can cause dangerously slow breathing, which can be life-threatening, even at recommended doses. The risk is heightened when starting the medication or increasing the dose, and for those taking medications that depress breathing, consuming alcohol, or having conditions like COPD, asthma, or a head injury.

• Opioid Overdose Risk: Follow the prescription exactly to avoid overdose. Keep oxycodone out of reach of children, pets, and visitors to prevent accidental ingestion. The risk is elevated for individuals with a history of opioid use disorder or previous overdose, those taking high doses, and those consuming alcohol.

• Impaired Concentration and Drowsiness: Oxycodone may cause extreme drowsiness and impair your ability to concentrate. Avoid alcohol and other medications that cause drowsiness, such as benzodiazepines, muscle relaxants, and sleep aids, as these effects may increase.

• Drug Interactions: Oxycodone interacts with various medications. Inform your healthcare team about all medications you are taking to ensure compatibility. Do not make any changes to your medication regimen without consulting your healthcare provider.

• Harm to Newborns: Long-term use during pregnancy can lead to newborn dependency due to oxycodone passing through the placenta.

• Physical Dependence and Withdrawal: Regular long-term use can lead to physical dependence, resulting in withdrawal symptoms such as anxiety, restlessness, and sweating if the medication is stopped suddenly or the dose is reduced quickly.

• Low Blood Pressure: Oxycodone may cause significant drops in blood pressure, particularly when standing up from a seated or lying position, leading to dizziness or fainting. Rise slowly to avoid these effects.

• Low Adrenal Hormone Levels: Long-term use may lead to reduced adrenal hormone levels, causing symptoms like fatigue and nausea. Consult your healthcare provider if you experience these symptoms.

• Seizures: Oxycodone may increase seizure risk, especially in those with a history of seizures. Seek medical help immediately if a seizure occurs during your treatment.

Contraindications: Oxycodone should not be used under the following conditions due to potential serious health risks:

• Severe respiratory depression
• Severe asthma
• Blockage in the stomach passageway
• Allergy to oxycodone

If any of these conditions apply to you, please discuss them with your healthcare provider before using this medication.

When using this medication, some individuals may experience common side effects, which are usually mild but should be discussed with a healthcare provider if they persist or worsen. These include nausea, constipation, vomiting, itching, headache, dizziness, weakness, sleepiness, and trouble sleeping.

Other side effects have also been noted, such as stomach pain, chills, diarrhea, cough, and shortness of breath. While these may not occur frequently, it's important to contact a healthcare provider if they are severe or persistent.

There are also rare but serious side effects that require immediate medical attention. These include dangerously slow breathing, indicated by trouble breathing or bluish-colored lips, fingers, or toes. An overdose may be identified by symptoms such as unresponsiveness, slowed breathing, a slow heartbeat, extreme sleepiness, or cold and clammy skin. Signs of opioid withdrawal, such as anxiety, suicidal thoughts, restlessness, irritability, runny nose, yawning, sweating, chills, and wide pupils, also warrant urgent care. Additionally, a serious allergic reaction may occur, characterized by an itchy, red rash, shortness of breath, chest tightness, or swelling of the lips, tongue, throat, face, or eyes, and should be treated immediately.