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When taking this medication, you might experience some mild side effects such as nausea, vomiting, stomach or abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination. These are generally not serious and often improve over time. However, if they persist or worsen, it's important to consult your healthcare provider.

There are more significant side effects to be aware of, including persistent nausea or vomiting, irregular heartbeat, muscle cramps, fainting, confusion, or dizziness. These require prompt attention from a healthcare professional. Additionally, though rare, seizures are a very serious side effect that necessitates immediate medical assistance.

Allergic reactions to this medication are uncommon but can be severe. Seek urgent medical help if you experience symptoms such as a rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. Always be vigilant for any other side effects not mentioned here and consult with your healthcare provider if you encounter any.

This medication can interact with certain substances, including riociguat. Additionally, some drugs may alter how theophylline is metabolized in your body, impacting its effectiveness. Such drugs include cimetidine, disulfiram, fluvoxamine, interferon, mexiletine, rifampin, seizure medications like carbamazepine and phenytoin, St. John's wort, ticlopidine, and viloxazine. Smoking tobacco or marijuana can lower the levels of theophylline in your blood. Inform your healthcare provider if you smoke or have recently quit.

Caffeine and alcohol may heighten the side effects of theophylline. It is advisable to limit the intake of caffeinated or alcoholic beverages, such as coffee, tea, and colas, as well as chocolate and over-the-counter products with caffeine. Theophylline is closely related to aminophylline and oxtriphylline, so avoid using medications containing these substances concurrently.

This drug might also affect certain laboratory tests, like those for blood sugar, cholesterol, uric acid, and dipyridamole-thallium imaging, potentially leading to inaccurate results. Ensure that all medical professionals involved in your care are aware of your theophylline use.