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Antidepressant medications, such as Vilazodone (Viibryd), are commonly prescribed for treating depression and other mood disorders. While they can offer significant benefits, there are important safety considerations and potential risks to be aware of. Below is a summary of vital warnings and precautions:

• Risk of Suicidal Thoughts or Behavior: Antidepressants may increase the risk of suicidal thoughts and behavior, particularly in individuals aged 24 years or younger. This risk is heightened during the initial months of treatment or following a dose adjustment. It's crucial to monitor for any signs of worsening depression or unusual mood changes and report them to your healthcare provider immediately.

• Serotonin Syndrome: This rare but potentially life-threatening condition can occur if there's an excess of serotonin in the body, often when combined with other serotonergic medications. Symptoms include a rapid heart rate, sweating, muscle stiffness, fever, and confusion. Seek emergency medical attention if these symptoms develop.

• Increased Risk of Bleeding: Vilazodone may elevate the risk of bleeding, especially when taken with other medications such as non-steroidal anti-inflammatory drugs, aspirin, or warfarin. Be vigilant for signs of serious bleeding, such as persistent bruising, difficult-to-control bleeding, or dark stools, and inform your healthcare provider promptly.

• Hyponatremia (Low Sodium Levels): This medication can cause low sodium levels in the blood, leading to symptoms like headache, confusion, and weakness. Older adults and those taking diuretics are at higher risk. Contact your provider if you experience these symptoms, as severe cases can result in serious complications.

• Eye Issues: Vilazodone can cause pupil dilation, which may trigger problems in individuals with angle-closure glaucoma. It's advisable to have an eye exam before starting treatment if you have a history of glaucoma, and report any eye discomfort or changes in vision to your provider.

• Worsening of Mania or Hypomania: In those with bipolar disorder, Vilazodone may induce manic or mixed episodes. It's important to disclose any history of bipolar disorder or manic episodes to your healthcare provider.

• Sexual Dysfunction: Some individuals may experience sexual side effects, including delayed ejaculation, reduced libido, or erectile dysfunction in males, and delayed orgasm or low libido in females. Discuss any pre-existing sexual health concerns with your provider before beginning treatment.

Contraindications: Do not use Vilazodone if you are currently taking or have recently stopped using a monoamine oxidase inhibitor (MAOI) within the past two weeks, as this may pose serious health risks.

Always consult your healthcare provider for personalized advice and report any concerning symptoms or side effects immediately.

When taking this medication, some common side effects you might experience include diarrhea, nausea, headache, vomiting, trouble sleeping, sleepiness, dizziness, and dry mouth. These effects are typically mild, but if they persist or worsen, it's important to consult with your healthcare provider for further advice and assistance.

There are also more serious side effects that, although rare, require immediate medical attention. These include suicidal thoughts and behaviors, serotonin syndrome (characterized by high fever, seizures, irregular heartbeat, confusion, and loss of consciousness), and serious bleeding issues such as bleeding that won't stop, persistent bruising, blood in the urine, or dark, tarry stools. Additionally, watch for symptoms like easy bleeding/bruising, numbness or tingling, tremors, inability to stay still, difficulty concentrating, confusion, memory problems, weakness, unsteadiness, decreased interest in sex, and changes in sexual ability, as these may require prompt medical evaluation.

Rarely, a severe allergic reaction may occur, with symptoms like rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing. If you notice any of these symptoms, seek medical help immediately. Although the list provided covers various potential side effects, if you notice any other unusual symptoms, reach out to your healthcare provider for guidance.

Some medications may interact with this drug, potentially causing increased risk of bleeding or other serious effects. For example, using this drug with other medications that can cause bleeding or bruising, such as antiplatelet drugs like clopidogrel, NSAIDs like ibuprofen or naproxen, and blood thinners such as dabigatran or warfarin, may heighten bleeding risk. Aspirin can also increase bleeding risk; however, if your doctor has advised you to use low-dose aspirin (81-162 milligrams daily) to prevent heart attack or stroke, you should continue unless directed otherwise by your doctor.

Avoid taking MAO inhibitors such as isocarboxazid, linezolid, and others listed during treatment with this drug, as this combination can lead to a dangerous, potentially fatal reaction. Most MAO inhibitors should not be used for two weeks before and after taking this medication. Consult your doctor on when to start or stop these medications.

Additionally, the risk of serotonin syndrome or toxicity is higher if you are using other drugs that increase serotonin levels, including certain antidepressants, street drugs like MDMA, St. John's wort, or tryptophan. This risk is particularly significant when starting or increasing the dose of these drugs.

Lastly, this medication may affect certain medical or laboratory tests, such as brain scans for Parkinson's disease, leading to incorrect results. Inform all healthcare providers and lab personnel that you are using this drug.