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Minocycline may cause mild side effects such as nausea, vomiting, diarrhea, lightheadedness, dizziness, or a spinning sensation. These effects usually subside on their own, but if they persist or worsen, it’s important to consult a healthcare professional. Some side effects can be more serious and require immediate attention. These include difficulty swallowing, changes in hearing like ringing or decreased hearing, joint pain or swelling, and signs of kidney or liver issues such as a change in urine output, yellowing of the skin or eyes, and dark urine. Additionally, tooth discoloration and changes in skin color might occur. Rarely, minocycline can lead to increased pressure in the brain, especially in overweight women of childbearing age or those with a history of this condition. Symptoms to watch for include persistent headaches, vision changes, or nausea and vomiting that do not subside. In such cases, seeking urgent medical care is crucial due to the risk of permanent vision loss. This medication may also rarely cause a serious intestinal condition due to C. difficile bacteria, potentially occurring during or after treatment. Symptoms such as severe diarrhea, abdominal pain, or blood in stools should prompt immediate medical consultation. Avoid using anti-diarrhea or opioid products as they may worsen the condition. Long-term use can lead to oral thrush or yeast infections, indicated by white patches in the mouth or changes in vaginal discharge. A severe allergic reaction is rare but requires emergency medical attention if symptoms like persistent fever, lymph node swelling, severe rash, itching, or difficulty breathing develop. This overview does not encompass all possible side effects, so any new or unusual symptoms should be discussed with a healthcare provider.