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The following safety information outlines critical warnings and precautions associated with the use of haloperidol injection. Please review these points carefully and discuss any concerns with your healthcare provider.

• Increased Mortality in Elderly with Dementia-Related Psychosis: Individuals aged 65 and older with dementia-related psychosis are at a heightened risk of death when using medications like haloperidol injection. Therefore, it is not recommended for this population. Inform your healthcare provider if you or someone you care for has dementia before beginning treatment.

• Life-Threatening Heart Rhythm Issues (QT Prolongation): Haloperidol injection may cause QT prolongation, a potentially fatal heart rhythm disorder. This risk is elevated in those with low potassium or magnesium levels, existing heart conditions, or those taking other QT-prolonging drugs. Notify your healthcare provider about all medications you are taking. Immediate medical attention is necessary if you experience symptoms like chest pain or severe lightheadedness.

• Uncontrolled Body Movements: Prolonged use or high doses of haloperidol injection can lead to irreversible uncontrolled movements, especially in older adults, females, or those with Parkinson's disease or certain dementias. Report any involuntary movements to your healthcare provider immediately.

• Neuroleptic Malignant Syndrome (NMS): This rare but serious condition can occur with antipsychotic medications, marked by symptoms such as high fever, muscle stiffness, and confusion. Seek urgent medical help if these symptoms arise.

• Increased Fall Risk: Haloperidol injection may cause drowsiness, low blood pressure, or balance issues, raising the risk of falls. Exercise caution when standing up and consult your provider if concerns about balance arise.

• Risk of Pneumonia: The use of haloperidol injection may lead to bronchopneumonia, particularly in older adults, smokers, or those with respiratory issues. Seek medical advice if you develop symptoms like fever or breathing difficulties.

• Low White Blood Cell Counts: Haloperidol may reduce white blood cell counts, increasing infection risk. Regular blood tests are necessary to monitor this condition. Contact your provider if you experience signs of infection.

• Pregnancy Considerations: Pregnant individuals should use haloperidol injection only if the benefits justify the potential risks to the unborn baby. Discuss with your healthcare provider if you are pregnant or planning to become pregnant.

Contraindications: Haloperidol injection should not be used in individuals with conditions such as coma, Parkinson's disease, Lewy body dementia, or any condition causing reduced brain activity, which may lead to symptoms like slowed breathing and reflexes. Consult your healthcare provider if any of these conditions apply to you.

When using this medication, some common side effects may occur, generally mild, but if they persist or worsen, consider consulting your healthcare provider. These include stiff or rigid muscles, tremors, trouble speaking, and other symptoms associated with parkinsonism, which can affect about 31% of users.

Other side effects reported by some individuals, which should be monitored, include spasms in the muscles of the eye, loss of muscle control, restlessness, stomach pain, and headaches. These are generally less severe but should be communicated to your healthcare provider if they become bothersome.

There are rare but serious side effects that warrant immediate medical attention. These include abnormal heart rhythms, characterized by symptoms such as chest pounding, shortness of breath, chest pain, and feeling faint or lightheaded. Neuroleptic malignant syndrome (NMS) is another critical condition that may present with fever, sweating, stiff muscles, confusion, and a rapid or irregular heartbeat. Additionally, be alert for signs of a severe infection, like fever, pale skin, fast heart rate, lightheadedness, and feeling unwell. Lastly, symptoms of a stroke, such as sudden numbness in the face, arms, or legs, especially on one side of the body, or sudden difficulty with speech, vision, walking, or understanding others, require urgent medical care.