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This medication carries important safety considerations that need to be understood to ensure its safe use. Below are key points regarding the risks, precautions, and specific instructions for taking this medication:

• Potential for Abuse and Addiction: This medication contains an opioid component, posing risks for misuse and addiction. This can lead to overdose and possibly death, even at recommended doses. Individuals with a personal or family history of substance abuse or mental health conditions are at increased risk.

• Respiratory Risks: It can cause dangerously slow breathing, especially within the first few days of treatment or if taken incorrectly. Combining it with alcohol or other sedatives increases this risk. Older adults, children under 18, and those with respiratory conditions or brain injuries should exercise caution.

• Cognitive and Sedative Effects: This medication may cause extreme drowsiness and impair focus and reaction times. The risk is heightened when combined with other sedatives like benzodiazepines or alcohol.

• Overdose Precautions: To prevent overdose, take the medication exactly as prescribed, using an accurate measuring device. Store securely to prevent accidental ingestion by children, pets, or others. Avoid alcohol consumption during treatment.

• Drug Interactions: Inform your healthcare provider about all other medications you are taking to avoid harmful interactions. Do not alter dosages without consulting your care team, as sudden changes can be dangerous.

• Pregnancy and Newborn Risks: Use during pregnancy is not recommended due to potential harm to the unborn child, including dependency and withdrawal symptoms in newborns. Consult your doctor if you are pregnant or planning to become pregnant.

• Blood Pressure and Adrenal Effects: This medication can cause low blood pressure, particularly when standing up, and may also lead to low adrenal hormone levels after extended use. Monitor for symptoms such as dizziness and nausea, and contact your healthcare provider if they occur.

• Seizure Risks: Those with a history of seizures should be aware that this medication may increase seizure frequency. Seek immediate medical attention if a seizure occurs.

• Gastrointestinal Concerns: It can slow gut movement, leading to constipation or bowel obstruction. Stay hydrated and consume fiber-rich foods to mitigate these effects. Avoid use if you have pre-existing bowel obstructions.

• Contraindications: Do not use this medication if you are under 6 years old, have severe asthma or breathing problems, stomach passageway obstructions, or allergies to its components.

In case of severe side effects such as slow breathing or difficulty waking, seek emergency medical assistance immediately. Always keep this medication in a secure location to prevent misuse or accidental ingestion.

When using hydrocodone, you may experience common side effects such as nausea, drowsiness, dizziness, lightheadedness, dry mouth, headache, constipation, and vomiting. These effects are usually mild and tend to improve after the first few doses. To help manage these, consider taking the medication with food and staying hydrated. If any of these symptoms persist or worsen, consult your healthcare provider.

Some individuals may also encounter other side effects like flushing, itching, rash, stomach pain, and a reduced appetite. These are typically less common, and you should inform your healthcare provider if they occur, especially if they become troublesome.

It's important to be aware of rare but serious side effects that require immediate medical attention. These include severe breathing difficulties, symptoms of overdose such as extreme drowsiness and confusion, and signs of an allergic reaction like rash and difficulty breathing. Additionally, if the medication is stopped suddenly after long-term use, withdrawal symptoms may occur, including anxiety and irritability.

Promptly seek medical help if you notice severe symptoms such as dangerously slow breathing, seizures, or excessive drowsiness. While serious allergic reactions are rare, immediate medical assistance is necessary if you experience swelling or severe dizziness. Always communicate any unexpected or severe side effects to your healthcare provider for appropriate guidance.

When taking Hydromet (hydrocodone/homatropine), be aware of potential interactions with other medications. Certain pain relievers, like mixed opioid agonist-antagonists (Butorphanol, Nalbuphine, pentazocine) and Naltrexone, can interact with Hydromet. Additionally, potassium tablets/capsules, pramlintide, and samidorphan may also have interactions. These combinations can increase the risk of severe side effects, such as slowed or shallow breathing and pronounced drowsiness or dizziness. Inform your doctor if you are using other substances that cause drowsiness or affect breathing, such as other opioids (codeine, Hydromorphone), alcohol, marijuana, sleep or anxiety medications (Alprazolam, Lorazepam, Zolpidem), muscle relaxants (Carisoprodol, Cyclobenzaprine), or antihistamines (Cetirizine, diphenhydramine).

Check all your medications for ingredients that might cause drowsiness and consult your pharmacist on how to use them safely. Some drugs can alter how Hydromet is removed from your body, impacting its effectiveness. Examples include certain antifungals (Ketoconazole), antibiotics (Erythromycin), HIV medications (tipranavir), and others like rifamycins (Rifabutin, Rifampin) and seizure medications (Carbamazepine, Phenytoin).

Hydromet may also interfere with lab tests, potentially leading to inaccurate results. Ensure that all healthcare professionals involved in your care are informed of your Hydromet use. Always keep your doctor and pharmacist updated on all medications and supplements you are taking to manage and prevent possible interactions effectively.