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Promethazine

Promethazine Coupons & Discount Card - Compare Prices Near You

generic Phenergan, Promethegan

Promethazine is a medication primarily used to prevent and treat nausea and vomiting associated with certain conditions, such as post-surgery and motion sickness. It can also be combined with other medications to manage severe allergic reactions like anaphylaxis and responses to blood transfusions. For milder allergic reactions, promethazine is an option when oral administration is not feasible. Additionally, it is helpful in inducing relaxation and sleepiness before and after surgery, during procedures, or during labor. Promethazine can enhance the effectiveness of certain opioid pain relievers, such as meperidine. As an antihistamine, promethazine works by blocking histamine, a substance produced during allergic reactions. Its additional effects, such as relieving nausea and providing sedation, result from its action on other natural substances like acetylcholine and specific brain regions. It is important to note that this drug is not recommended for children under 2 years old due to the heightened risk of side effects, including slow or shallow breathing. Please refer to the Warning section for more details.
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Promethazine WarningsPromethazine Side EffectsInteractionsFAQs

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1ML of 25MG/ML, Promethazine (1 Ampule)

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CVS

$20.16

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$1.01

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$2.00

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$2.48

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Promethazine dosage forms

The average cost for 1 Ampule of Promethazine (generic Phenergan, Promethegan) at 1ML of 25MG/ML is $1.01 with a free coupon. This is 7.97% off the average retail price of $12.67
DosageQuantityPrice fromPer unit
1ML of 25MG/ML1 Ampule$1.01$1.01
1ML of 50MG/ML1 Ampule$1.01$1.01

Promethazine Warnings

Promethazine should not be used by children younger than 2 years because it may cause serious (possibly fatal) slow/shallow breathing. When this medication is used by children 2 years and older, use the lowest effective dosage and avoid other drugs that affect breathing. Get medical help right away if slow/shallow breathing occurs. In children, drugs for nausea should only be used in cases of prolonged vomiting of a known cause. Avoid use of promethazine in children with liver disease (including possible Reye's syndrome). This medication can cause severe tissue damage, possibly requiring surgery. Tell your health care professional right away if you have burning, pain, redness, swelling, or numbness at or near the injection site. If this occurs, the injection should be stopped and the injection site checked. It is preferred that this medication be given by injection into a muscle. There may be an increased risk of side effects if this medication is given by injection into a vein. This medication must not be given by injection under the skin.

Promethazine Side Effects

You might experience some common side effects like drowsiness, dizziness, constipation, blurred vision, or dry mouth while using this medication. These effects are typically mild and temporary. To ease dry mouth, consider using sugarless hard candy, ice chips, sugarless gum, drinking water, or saliva substitutes.

However, if any side effects persist or worsen, it's important to seek advice from a healthcare professional. Although most people do not experience serious side effects, be vigilant for any signs of infection, such as a persistent sore throat, fever, or chills. Other serious side effects to watch for include loss of coordination, fainting, confusion, slow heartbeat, tremors, unusual movements, mood changes, trouble urinating, easy bleeding/bruising, severe abdominal pain, or yellowing of the skin or eyes.

Seek immediate medical attention if you experience very serious side effects like slow or shallow breathing, seizures, or symptoms of a rare condition known as neuroleptic malignant syndrome, which includes fever, muscle stiffness, severe tiredness, confusion, sweating, irregular heartbeat, or dark urine. Also, although rare, a serious allergic reaction can occur, presenting as a rash, itching, swelling, severe dizziness, or trouble breathing. If you notice any such symptoms, seek medical help promptly. Always consult a healthcare provider for any effects not listed here.

Interactions

This medication can interact with certain products, including skin-applied antihistamines like diphenhydramine creams, ointments, or sprays, and medications such as Metoclopramide. Using this drug with other substances that can cause drowsiness or breathing difficulties may raise the risk of severe side effects, such as slow or shallow breathing and pronounced drowsiness or dizziness. Inform your doctor or pharmacist if you're using other products like opioid pain relievers or cough suppressants (e.g., codeine, hydrocodone), alcohol, marijuana, sleep or anxiety medications (e.g., Alprazolam, Lorazepam, Zolpidem), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), or other antihistamines (e.g., Cetirizine, diphenhydramine). Always check the labels on your medications, including those for allergies or cold symptoms, since they might contain ingredients that cause drowsiness. Consult your pharmacist about using these products safely. Additionally, this medication may affect certain laboratory tests, like some pregnancy or blood sugar tests, potentially leading to inaccurate results. Ensure that lab personnel and all your healthcare providers are aware that you are using this drug.
Promethazine FAQs
Can I take Benadryl while taking promethazine?

It is generally not recommended to take Benadryl (diphenhydramine) and promethazine together without consulting a healthcare provider. Both medications are antihistamines and can cause increased sedation, drowsiness, and other side effects when combined. It is important to seek advice from a healthcare professional to ensure safe use.

Promethazine and Zofran are not the same. Promethazine is an antihistamine used to treat allergy symptoms, nausea, and vomiting, while Zofran (ondansetron) is a selective serotonin 5-HT3 receptor antagonist used primarily to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. They work differently and are used for different purposes.

A suitable substitute for Benadryl (diphenhydramine) could be another antihistamine, such as cetirizine (Zyrtec) or loratadine (Claritin). These alternatives are also used to relieve allergy symptoms and are less likely to cause drowsiness compared to Benadryl. However, it is important to consult with a healthcare provider to determine the most appropriate option based on individual needs and medical history.

Promethazine is used to treat allergy symptoms, such as itching, runny nose, and sneezing. It is also used to prevent motion sickness, treat nausea and vomiting, and as a sedative or sleep aid. Additionally, it may be used to enhance the effects of certain pain medications.

Yes, promethazine is effective for treating nausea. It is an antihistamine that is commonly used to relieve symptoms of nausea and vomiting. However, it is important for individuals to use it under the guidance of a healthcare professional, as it may have side effects and interactions with other medications.

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