Progesterone Wettable

Drug Details

Wettable progesterone is a form of progesterone powder designed to blend more easily with melted bases, making it particularly suitable for compounding high-concentration troches or suppositories. This enhanced compatibility facilitates the preparation of these dosage forms, especially when progesterone concentrations exceed 200 mg. However, it's important to note that higher concentrations of progesterone can result in increased bitterness, which may affect the palatability of troches and, consequently, patient compliance. Therefore, while wettable progesterone offers advantages in certain formulations, careful consideration of dosage and patient experience is essential.