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This document outlines crucial safety information and warnings associated with the use of ipratropium/albuterol solution. It's essential to understand these risks and take necessary precautions. Please consult your healthcare provider for any concerns or questions.

• Narrowing of Airways (Bronchospasm): Although very rare, the use of ipratropium/albuterol can cause bronchospasm, leading to breathing difficulties, wheezing, coughing, and chest discomfort. Seek immediate medical attention if shortness of breath occurs after using this medication.

• Heart Issues: This medication can affect blood pressure and heart rate, potentially worsening existing heart conditions, especially with overuse. Be aware of symptoms such as dizziness, fatigue, tremor, rapid heartbeat, or weakness, and inform your healthcare provider if these occur. This is particularly important for individuals with high blood pressure, heart failure, or heart rhythm problems.

• Eye Concerns: Ipratropium/albuterol may increase eye pressure and exacerbate glaucoma. Consult your eye care provider before use if you have glaucoma or other eye conditions. Avoid spraying the medication into your eyes to prevent pain, discomfort, or vision changes.

• Urinary Issues: Those with prostate problems should use this medication cautiously, as it can worsen urinary difficulties. Contact your provider if you experience trouble urinating.

• Severe Allergic Reactions: There is a risk of severe allergic reactions, including facial swelling, shock, and anaphylaxis. Seek immediate medical help if you develop hives, rash, swelling of the lips or tongue, or difficulty breathing.

• Low Potassium Levels: Overdosing can cause low potassium levels, leading to tiredness, weakness, muscle cramps, a racing heart, and a tingling sensation in the extremities. Do not exceed the prescribed dosage and seek medical attention if breathing does not improve.

Contraindications:

• Do not use if you have an allergy to atropine or similar anticholinergic medications.

Always follow the prescribed dosage and consult your healthcare provider if you have any conditions or are taking other medications that might interact with ipratropium/albuterol solution.

Common side effects:

• Headache
• Dizziness
• Nausea
• Dry mouth
• Shaking
• Nervousness
• Constipation

Less common but important to monitor:

• Lung problems
• Sore throat
• Diarrhea
• Raised blood pressure
• Urinary tract infections
• Bronchitis
• Pneumonia

Serious side effects:

• Chest pain
• Fast or irregular heartbeat
• Rapid breathing
• Confusion
• Eye pain or vision changes
• Sudden worsening of breathing problems
• Serious allergic reactions
• Rash
• Severe dizziness
• Difficulty breathing

Interactions with high risk of serious adverse effects and should be avoided:

• Levalbuterol

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Acebutolol
• Amineptine
• Amitriptyline
• Amitriptylinoxide
• Amoxapine
• Arotinolol
• Atenolol
• Atomoxetine
• Befunolol
• Betaxolol
• Bevantolol
• Bisoprolol
• Bopindolol
• Bucindolol
• Bupranolol
• Carteolol
• Carvedilol
• Celiprolol
• Clomipramine
• Clozapine
• Desipramine
• Dibenzepin
• Dilevalol
• Doxepin
• Esmolol
• Glucagon
• Glycopyrrolate
• Glycopyrronium Tosylate
• Imipramine
• Iobenguane I 123
• Labetalol
• Landiolol
• Levalbuterol
• Levobunolol
• Lofepramine
• Melitracen
• Mepindolol
• Methacholine
• Metipranolol
• Metoprolol
• Nadolol
• Nebivolol
• Nortriptyline
• Opipramol
• Oxprenolol
• Penbutolol
• Pindolol
• Practolol
• Propranolol
• Protriptyline
• Quetiapine
• Revefenacin
• Scopolamine
• Secretin Human
• Sotalol
• Talinolol
• Tertatolol
• Tianeptine
• Timolol
• Tiotropium
• Trimipramine

Interactions with low risk that usually do not require a change in therapy:

• Betel Nut
• Digoxin