Doxepin Coupons & Discount Card – Guaranteed Prices from $11.26
generic Zonalon, Prudoxin, Silenor
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100MG, Doxepin (30 Capsules)
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$20.70
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$11.26
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$13.38
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$15.46
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$22.02
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$11.26
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Doxepin dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 10MG | 30 Capsules | $2.87 | $0.1 |
| 100MG | 30 Capsules | $9.87 | $0.33 |
| 150MG | 30 Capsules | $18.65 | $0.62 |
| 25MG | 30 Capsules | $4.41 | $0.15 |
| 50MG | 30 Capsules | $7.2 | $0.24 |
| 75MG | 30 Capsules | $9.84 | $0.33 |
Doxepin Warnings
Antidepressant medications, such as doxepin (Sinequan), are prescribed for the treatment of depression and other mood disorders. While these medications can be beneficial, they also carry certain risks and require careful monitoring. Below are important safety and warning considerations to keep in mind:
Suicidal Thoughts and Behavior: Individuals, particularly those aged 24 and younger, may experience worsening depression or suicidal thoughts when taking antidepressants. It's crucial to monitor for any mood or behavioral changes, especially during the initial months of treatment or following a dosage adjustment. Contact your healthcare provider immediately if you notice any unusual mental or mood changes.
Bipolar Disorder Considerations: Doxepin (Sinequan) is not recommended for treating bipolar disorder as it may trigger manic episodes. Your healthcare provider should evaluate you for bipolar disorder and assess your risk before initiating treatment with this medication.
Serotonin Syndrome Risk: There is a risk of serotonin syndrome when doxepin (Sinequan) is taken with other medications that increase serotonin levels, such as MAOIs, SSRIs, SNRIs, TCAs, NRIs, and certain herbal supplements like St. John's Wort. Symptoms can include sweating, tremors, rapid heartbeat, insomnia, and fever. In severe cases, this condition can lead to high blood pressure, seizures, or even death. Seek immediate medical attention if you experience these symptoms.
Drowsiness: Doxepin (Sinequan) can cause drowsiness, increasing the risk of falls and confusion, especially in individuals over 65. Avoid activities that require full alertness, such as driving, until you know how the medication affects you. Combining doxepin with alcohol or other sedative medications can enhance this effect. Discuss with your healthcare provider about adjusting your dosage or considering alternative treatments if drowsiness is problematic.
Contraindications: Doxepin (Sinequan) should not be used if you have certain conditions like glaucoma or urinary retention, as it may exacerbate these issues. Consult your healthcare provider if you have these or other medical concerns before starting the medication.
Always discuss any concerns or questions with your healthcare provider to ensure safe and effective use of antidepressant medications. In case of an overdose, seek emergency medical attention immediately.
Doxepin Side Effects
Common side effects:
- drowsiness
- blurred vision
- dry mouth
- constipation
- trouble urinating
Less common but important to monitor:
- skin rash
- nausea
- vomiting
- diarrhea
- headache
- dizziness
- sweating
- weight gain
Serious side effects:
- worsened depression
- suicidal thoughts or actions
- severe dizziness
- fast or irregular heartbeat
- fainting
- seizures
- eye pain or redness
- widened pupils
- significant vision changes
- allergic reaction characterized by rash, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing
Doxepin Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- MAO inhibitors (isocarboxazid, Linezolid, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, Tranylcypromine)
- Bepridil
- Bromopride
- Cisapride
- Dronedarone
- Eliglustat
- Grepafloxacin
- Levomethadyl
- Mesoridazine
- Metoclopramide
- Pimozide
- Piperaquine
- Ranolazine
- Saquinavir
- Sparfloxacin
- Terfenadine
- Thioridazine
- Ziprasidone
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Cimetidine
- St. John's Wort
- Antidepressants (paroxetine, Fluoxetine, Fluvoxamine)
- Medications for irregular heart rhythms (quinidine, Propafenone)
- Amiodarone
- Macrolide antibiotics (Erythromycin)
- Clonidine
- Codeine
- Hydrocodone
- Alprazolam
- Lorazepam
- Zolpidem
- Carisoprodol
- Cyclobenzaprine
- Cetirizine
- Diphenhydramine
- Acecainide
- Aceclofenac
- Amitriptyline
- Amphetamine
- Aripiprazole
- Arsenic Trioxide
- Benzhydrocodone
- Bretylium
- Buprenorphine
- Bupropion
- Clarithromycin
- Chloroquine
- Clozapine
- Crizotinib
- Dextromethorphan
- Dofetilide
- Epinephrine
- Escitalopram
- Fentanyl
- Fluoxetine
- Haloperidol
- Ibuprofen
- Ketoconazole
- Lithium
- Methadone
- Metronidazole
- Ondansetron
- Oxycodone
- Paroxetine
- Phenytoin
- Procainamide
- Quinine
- Risperidone
- Sotalol
- Sumatriptan
- Tamoxifen
- Tramadol
- Venlafaxine
- Vortioxetine
Interactions with low risk that usually do not require a change in therapy:
- Alcohol
- Cannabis
- Hormonal contraceptives (Ethinyl Estradiol, Levonorgestrel)
Is doxepin a strong sleeping pill?
Doxepin is primarily an antidepressant, but at lower doses, it is used to treat insomnia due to its sedative properties. It can be effective for improving sleep, particularly in individuals who have difficulty staying asleep. However, its strength as a sleeping aid can vary from person to person. It is important for individuals to consult with their healthcare provider to determine if doxepin is appropriate for their specific sleep issues.
Is doxepin the same as trazodone?
Doxepin and trazodone are not the same. They are both medications used to treat different conditions. Doxepin is primarily used as an antidepressant and for treating anxiety disorders, while trazodone is mainly used to treat depression and sometimes prescribed for insomnia. They belong to different classes of medications and have different mechanisms of action.
Why is doxepin a high risk medication?
Doxepin is considered a high-risk medication primarily due to its potential for causing significant side effects and interactions. It can lead to sedation, confusion, and an increased risk of falls, especially in older adults. Additionally, doxepin can have anticholinergic effects, which may cause dry mouth, constipation, urinary retention, and blurred vision. It also has the potential to interact with other medications, leading to increased side effects or reduced efficacy. Careful monitoring and management are necessary when prescribing doxepin to minimize these risks.
What is the black box warning on doxepin?
Doxepin carries a black box warning for an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults, particularly during the initial treatment period or when the dose is adjusted. It is important for healthcare providers to monitor patients closely for any changes in mood, behavior, or thoughts of self-harm.
Does doxepin work as well as Ambien?
Doxepin and Ambien (zolpidem) are both used to treat insomnia, but they work differently and may have varying effectiveness depending on the individual. Doxepin is a tricyclic antidepressant that, at low doses, is used for sleep maintenance insomnia. Ambien is a sedative-hypnotic specifically designed for short-term treatment of sleep initiation insomnia. The effectiveness of each medication can vary based on the specific sleep issues and individual response. It is important for patients to consult with their healthcare provider to determine which medication is more suitable for their needs.