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When considering the use of nadolol (Corgard), it is important to be aware of certain safety precautions and potential risks. Below is a summary of key warnings and instructions to help you use this medication safely.

• Do Not Discontinue Suddenly: If you have conditions like chest pain (angina) or heart disease, including coronary artery disease or high blood pressure, do not stop taking nadolol (Corgard) abruptly without medical guidance. Sudden cessation can exacerbate your condition or increase the risk of chest pain and heart attack. Consult your healthcare provider to develop a plan to gradually decrease your dosage if discontinuation is necessary.
• Heart Failure Concerns: Individuals with heart failure must ensure their symptoms are well-managed before using nadolol (Corgard), as it may worsen their condition. Even those without heart failure might face a risk over time. Contact your doctor if you notice symptoms like swelling in the ankles, legs, or lungs, and difficulty breathing.
• Breathing Difficulties: Nadolol (Corgard) can constrict blood vessels in the lungs, potentially complicating breathing, especially for those with asthma or COPD. Inform your doctor about any existing respiratory issues before beginning treatment.
• Blood Sugar Monitoring: This medication may obscure signs of low blood sugar, such as rapid heartbeat or tremors, particularly if you are diabetic and using medications like insulin or glipizide. Discuss blood sugar monitoring strategies with your healthcare provider.
• Surgical Risks: If you are scheduled for major surgery that involves anesthesia, inform your surgeon that you are taking nadolol (Corgard) as it may lower your heart rate. This information is vital for appropriate monitoring during surgery.
• Overactive Thyroid: Patients with hyperthyroidism should talk to their healthcare provider before stopping nadolol (Corgard) because it may mask heart-related symptoms. Sudden withdrawal could trigger a "thyroid storm," characterized by high fever, rapid heartbeat, and fainting.

Contraindications: Avoid using nadolol (Corgard) if you have asthma or uncontrolled heart failure symptoms, as these conditions may pose serious health risks. Always consult with your healthcare provider before starting or stopping this medication.

Common side effects:

• Dizziness
• Drowsiness
• Weakness
• Persistent cough
• Cold hands and feet

Less common but important to monitor:

• Very slow heartbeat
• Extreme tiredness
• Nausea
• Indigestion

Serious side effects:

• Heart failure symptoms (trouble breathing, unusual tiredness, chest pain, swelling in legs/ankles/feet)
• Bronchospasm (chest tightness, difficulty breathing, wheezing, severe dizziness)
• Serious allergic reaction (rash, severe dizziness, difficulty breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Epinephrine
• Fingolimod

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Albuterol
• Ceritinib
• Clonidine
• Crizotinib
• Diltiazem
• Dronedarone
• Fenoldopam
• Formoterol
• Indacaterol
• Iobenguane I 131
• Iohexol
• Lacosamide
• Levalbuterol
• Lidocaine
• Olodaterol
• Oxymetazoline
• Ponesimod
• Rivastigmine
• Salmeterol
• Siponimod
• Terbutaline
• Verapamil
• Vilanterol

Interactions with low risk that usually do not require a change in therapy:

• Codeine
• Hydrocodone
• Alcohol
• Marijuana (cannabis)
• Alprazolam
• Lorazepam
• Zolpidem
• Carisoprodol
• Cyclobenzaprine
• Cetirizine
• Diphenhydramine
• Ibuprofen
• Naproxen