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Quetiapine (Seroquel) is a medication with several important safety warnings that should be carefully considered before use. It is vital to discuss any concerns with your healthcare provider. Below is a summary of the essential safety information:

• Increased Mortality in Elderly with Dementia-Related Psychosis: Individuals aged 65 and older with dementia-related psychosis face a heightened risk of death when using quetiapine. This medication is not recommended for this population. Notify your provider if dementia is present.

• Worsening Depression and Suicidal Thoughts: Quetiapine may exacerbate depression and increase the risk of suicidal thoughts, particularly in individuals under 24 years old, during the initial treatment weeks, or following a dosage change. Seek immediate medical attention if suicidal thoughts or unusual behaviors occur.

• Neuroleptic Malignant Syndrome: This rare, life-threatening condition may arise with antipsychotic medications like quetiapine. Symptoms include fever, sweating, muscle stiffness, confusion, and irregular heartbeat. Immediate medical attention is necessary if these symptoms appear.

• Metabolic Changes: Quetiapine can lead to weight gain and increased blood sugar and cholesterol levels. Regular blood tests and a healthy lifestyle are recommended to manage these risks.

• Movement Disorders: Long-term use may cause involuntary movements such as eye twitching or lip-smacking. Report any uncontrolled movements to your provider promptly.

• Blood Pressure Changes and Fall Risk: Quetiapine may cause tiredness, low blood pressure, and balance issues, increasing fall risk. Rise slowly from seated or lying positions, and consult your provider if falls occur.

• Risk of Infection: Quetiapine can lower white blood cell counts, increasing infection risk. Regular blood tests are necessary to monitor WBC levels. Contact your provider if infection symptoms develop.

• Heart Rhythm Disturbances (QT Prolongation): This medication may cause serious heart rhythm issues. Immediate medical help is required if you experience chest pounding, shortness of breath, chest pain, or faintness.

• Seizure Risk: Inform your provider of any seizure history before starting quetiapine, as it may provoke seizures.

• Hypothyroidism: Quetiapine can lower thyroid hormone levels. Regular thyroid function tests are advised. Report symptoms like fatigue, weight gain, or feeling cold to your provider.

• High Prolactin Levels: This can lead to fertility issues, breast changes, sexual dysfunction, menstrual irregularities, and bone weakness. Monitoring prolactin levels during treatment is important.

• Cognitive Impairment and Drowsiness: Quetiapine may cause significant drowsiness and concentration issues, particularly when combined with other sedative medications. Ensure you understand how quetiapine affects you before driving or operating machinery.

Always communicate openly with your healthcare provider regarding your medical history and any medications you are taking to ensure safe use of quetiapine.

When using this medication, some individuals may experience common side effects that are generally mild. These include headaches, agitation, sleepiness, dizziness, dry mouth, constipation, and pain. If these symptoms persist or worsen, it is advisable to consult a healthcare provider for guidance and reassurance.

Additionally, there are other side effects that have been reported, such as difficulty controlling muscle movements and weight gain. If these or any other unusual symptoms occur, it is important to monitor them and seek advice if they become concerning.

Although rare, there are severe side effects associated with this medication that necessitate immediate medical attention. These include a fast heart rate, vomiting, weakness, indigestion, fatigue, and nasal congestion. If you experience any of these serious symptoms, it is crucial to seek urgent medical care to ensure your safety and well-being.