Abacavir-lamivudine-zidovudine Coupons & Discount Card - Compare Prices Near You

This medication contains important safety information that you must consider before use. Please carefully review the following points and consult your healthcare provider if you have any questions or concerns.

• Allergic Reactions: Abacavir, a component of this medication, can cause severe, potentially fatal allergic reactions, typically within the first six weeks of treatment. A genetic test (HLA B5701) is necessary to determine your risk. If the test indicates a high risk or if you have a history of allergic reaction to this medication, you must avoid using it. Look out for symptoms such as rash, itching, swelling, severe dizziness, trouble breathing, fever, extreme tiredness, nausea, vomiting, diarrhea, stomach pain, muscle aches, sore throat, mouth sores, or cough. If you experience these symptoms, stop taking the medication immediately and seek medical attention.

• Blood and Bone Marrow Concerns: The zidovudine in this medication can impair bone marrow function, leading to anemia and a weakened immune system, especially in those with advanced HIV. Regular blood tests are required to monitor your blood cell counts. If you experience unusual tiredness, fast breathing, pale skin, or signs of infection, seek medical help promptly.

• Muscle Issues: Prolonged use of this medication may lead to muscle pain or weakness. If you develop unexplained fatigue, muscle pain, or weakness, contact your healthcare provider immediately.

• Liver Problems: This medication may rarely cause severe liver issues, including lactic acidosis. Women and obese patients are at higher risk. Symptoms include nausea, vomiting, stomach pain, unusual tiredness, dark urine, yellowing of the eyes or skin, deep or rapid breathing, and drowsiness. Discontinue use and seek emergency medical attention if these symptoms occur.

• Hepatitis B Concerns: If you have hepatitis B and HIV, stopping this medication without guidance may worsen hepatitis symptoms. Consult your doctor before discontinuing use, and ensure regular monitoring of liver tests after stopping.

• Immune Reconstitution Syndrome: As your immune system recovers, it may trigger inflammation while fighting infections. Notify your healthcare provider if you experience fever, difficulty breathing, or abrupt health changes after starting this medication.

• Heart Attack Risk: There may be an increased risk of heart attack, particularly in individuals with high blood pressure, high cholesterol, or diabetes. Discuss your medical history and current medications with your healthcare provider.

• Fat Redistribution: Some patients may experience changes in body fat distribution, such as increased fat in the abdomen and upper back, with decreased fat in the face, arms, legs, and buttocks. Switching medications may alleviate this, though changes may not be fully reversible.

If you suspect an overdose or experience severe reactions, seek emergency medical assistance immediately. Always inform your healthcare provider of any conditions or medications you are taking to avoid adverse interactions.

Common side effects:

• Nausea
• Vomiting
• Headache
• Tiredness
• Fatigue
• Diarrhea
• Fevers
• Chills
• Depressed mood

Less common but important to monitor:

• Muscle pain
• Rash
• Anxiety
• Cold or flu-like symptoms

Serious side effects:

• Unexplained weight loss
• Severe tiredness
• Persistent muscle aches
• Severe headaches
• Joint pain
• Numbness or tingling in the extremities
• Vision changes
• Signs of infection like fever and swollen lymph nodes
• Symptoms of an overactive thyroid such as irritability and a rapid heartbeat
• Pancreatitis
• Guillain-Barre syndrome
• Changes in body fat distribution

Interactions with high risk of serious adverse effects and should be avoided:

• Ganciclovir, Trimethoprim, and certain cancer chemotherapies like doxorubicin (drugs that may decrease bone marrow function or lower blood cell counts).
• Rifampin
• Valproic Acid
• Clarithromycin
• Emtricitabine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Orlistat
• Probenecid
• Ribavirin
• Sorbitol
• Stavudine
• Cabotegravir
• Dapsone
• Doxorubicin Hydrochloride Liposome
• Flucytosine
• Horsetail
• Pexidartinib
• Pyrazinamide
• Pyrimethamine
• Vinblastine
• Vincristine
• Vincristine Sulfate Liposome

Interactions with low risk that usually do not require a change in therapy:

• Acetaminophen
• Fluconazole
• Interferon Beta-1a
• Methadone
• Nelfinavir
• Rifabutin
• Rifapentine
• Tipranavir