Colchicine-probenecid Coupons & Discount Card – Guaranteed Prices from $40.07
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0.5-500MG, Colchicine-probenecid (90 Tablets)
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CVS
$61.74
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$40.07
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Walmart
$87.77
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$91.19
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$103.29
COUPON PRICEColchicine-probenecid savings card
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$40.07
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ID
PCN
GRP
019876
LH51559221
CHIPPO
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Colchicine-probenecid dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 0.5-500MG | 90 Tablets | $40.07 | $0.45 |
Colchicine-probenecid Warnings
This safety guide provides essential information about the potential risks and necessary precautions when using this medication. It is crucial to review these details and consult your healthcare provider if you have any concerns.
Increased Risk of Gout Attacks: Some individuals may experience more frequent gout flares when starting on probenecid/colchicine. Should this occur, contact your healthcare team immediately. They may prescribe an additional medication, such as allopurinol (Zyloprim), to help manage and prevent gout attacks.
Kidney Stones and Injury: The use of probenecid/colchicine can lead to the development of kidney stones, which may sometimes result in kidney injury. This risk is elevated in individuals with a history of kidney issues or those who have previously had kidney stones. Factors increasing risk include dehydration and pre-existing kidney problems.
Abnormal Blood Conditions: Individuals with a genetic condition known as G6PD deficiency are at an increased risk for rare but serious blood disorders when taking probenecid. If you have this deficiency or experience related symptoms, consult your prescriber about alternative gout medications that may be safer for you.
Contraindications
This medication should not be used under certain conditions due to potential serious health risks. If any of the following apply to you, speak with your healthcare provider before starting the medication:
- Experiencing a current gout attack
- Children under 2 years of age
- Currently pregnant
- Existing abnormal blood conditions
- Presence of uric acid kidney stones
Always ensure your healthcare provider is aware of your medical history to avoid adverse effects.
Colchicine-probenecid Side Effects
Common side effects:
- Headache
- Dizziness
- Nausea
- Vomiting
- Diarrhea
Less common but important to monitor:
- Kidney stones
- Sudden gout attacks
- Nerve pain
- Muscle weakness
- Hair loss
Serious side effects:
- Persistent nausea or vomiting
- Severe diarrhea
- Muscle pain
- Numbness or tingling in extremities
- Unusual bleeding or bruising
- Signs of infection like a persistent sore throat or fever
- Dark urine
- Yellowing of the skin or eyes
- Fast heartbeat
- Shortness of breath
- Signs of kidney problems, such as changes in urination
- Severe allergic reaction (rash, severe dizziness, itching or swelling, difficulty breathing)
Colchicine-probenecid Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- Amiodarone
- Atazanavir
- Boceprevir
- Carvedilol
- Clarithromycin
- Cobicistat
- Conivaptan
- Cyclosporine
- Darunavir
- Diltiazem
- Dronedarone
- Erythromycin
- Flibanserin
- Idelalisib
- Indinavir
- Itraconazole
- Ketoconazole
- Ketorolac
- Lapatinib
- Lopinavir
- Nefazodone
- Nelfinavir
- Nilotinib
- Posaconazole
- Quinidine
- Ranolazine
- Ritonavir
- Saquinavir
- Sunitinib
- Telaprevir
- Telithromycin
- Tipranavir
- Vemurafenib
- Verapamil
- Voriconazole
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Abametapir
- Amprenavir
- Aprepitant
- Atorvastatin
- Avibactam
- Baricitinib
- Capmatinib
- Cephalexin
- Citalopram
- Crizotinib
- Deferiprone
- Delavirdine
- Doripenem
- Fenofibrate
- Fenofibric Acid
- Fluconazole
- Fluvoxamine
- Fosamprenavir
- Fosaprepitant
- Fosnetupitant
- Gemfibrozil
- Imatinib
- Indomethacin
- Interferon Alfa-2a
- Lasmiditan
- Letermovir
- Lovastatin
- Lumateperone
- Methotrexate
- Mibefradil
- Mifepristone
- Naproxen
- Netupitant
- Pegloticase
- Pexidartinib
- Pitavastatin
- Pravastatin
- Reserpine
- Rosuvastatin
- Sacituzumab Govitecan-hziy
- Simvastatin
- Tacrolimus
- Venetoclax
- Zalcitabine
Interactions with low risk that usually do not require a change in therapy:
- Amoxicillin
- Aspirin
- Bezafibrate
- Bismuth Subsalicylate
- CefditorenPivoxil
- Cefotaxime
- CefpodoximeProxetil
- Cefprozil
- Choline Magnesium Trisalicylate
- Ciprofibrate
- Ciprofloxacin
- Clofibrate
- Digoxin
- Enprofylline
- Ertapenem
- Fluvastatin
- Gatifloxacin
- Lorazepam
- Magnesium Salicylate
- Meropenem
- Norfloxacin
- Phenprocoumon
- Piretanide
- Pralatrexate
- Sodium Salicylate
- Sodium Thiosalicylate
- Zidovudine
- Zomepirac
What is colchicine probenecid used for?
Colchicine probenecid is used to treat chronic gouty arthritis. It helps to reduce the frequency of gout attacks by decreasing uric acid levels in the blood and reducing inflammation.
What should you not take with probenecid?
Probenecid can interact with several medications, so it is important to avoid taking it with certain drugs unless advised by a healthcare provider. Some medications that should be used cautiously or avoided with probenecid include:- Aspirin and other salicylates, as they can reduce the effectiveness of probenecid.- Certain antibiotics like penicillins and cephalosporins, as probenecid can increase their levels in the blood.- Methotrexate, as probenecid can increase its toxicity.- Nonsteroidal anti-inflammatory drugs (NSAIDs), which may have altered effects when taken with probenecid.It is essential to consult with a healthcare provider before combining probenecid with any other medications to ensure safety and efficacy.
Why is probenecid banned?
Probenecid is not banned for medical use; it is a legitimate medication used to treat gout and to increase the effectiveness of certain antibiotics. However, it is banned in sports by organizations like the World Anti-Doping Agency (WADA) because it can be used as a masking agent to hide the presence of performance-enhancing drugs in an athlete's system.
Which of the following medications can interact with probenecid?
Probenecid can interact with several medications. Some of these include:- Penicillins and cephalosporins: Probenecid can increase the levels of these antibiotics in the blood.- Methotrexate: Probenecid can increase methotrexate levels, potentially leading to toxicity.- Nonsteroidal anti-inflammatory drugs (NSAIDs): Probenecid can affect the excretion of NSAIDs.- Zidovudine: Probenecid can increase the levels of zidovudine.- Aspirin: High doses of aspirin can reduce the effectiveness of probenecid.It is important for patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Has probenecid been discontinued?
Probenecid has not been discontinued and is still available as a medication. It is used primarily to treat gout and to increase the levels of certain antibiotics in the body. However, availability may vary by region and specific formulations or brands. It is advisable to check with local pharmacies or healthcare providers for the most current information regarding its availability.