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When taking this medication, you might experience mild side effects such as nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, or constipation. These are relatively common and often resolve on their own. If dry mouth is bothersome, consider using sugarless candy or gum, drinking water, or trying a saliva substitute for relief. Additionally, be aware that your urine and stools might turn blue-green; this is a harmless effect that will stop once the medication is discontinued.

In some cases, more serious side effects can occur. Seek medical attention if you notice hot, dry, flushed skin, decreased sweating, eye pain, or difficulty in urination. These could be indicators of underlying issues needing prompt evaluation. Furthermore, if you experience signs of kidney problems, such as changes in urination or painful urination, consult a healthcare professional.

There is a rare risk of very serious side effects, including signs of a hypertensive crisis like severe headache, irregular heartbeat, chest pain, or vision changes. These symptoms require immediate medical intervention. Symptoms indicative of liver problems, such as persistent nausea, unusual tiredness, dark urine, or yellowing of the skin or eyes, also warrant urgent care.

In rare instances, a severe allergic reaction may occur. Be alert for symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing. If these arise, seek emergency medical assistance. This overview does not cover all possible side effects, so if you notice any other unusual symptoms, contact your healthcare provider for advice.

This medication can interact with a wide range of other products. These include apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium supplements, pramlintide, tetrabenazine, some Parkinson’s medications (such as entacapone, levodopa, tolcapone), certain blood pressure medicines (like guanethidine, methyldopa), sulfonamide drugs (including sulfa antibiotics like sulfamethoxazole), and sympathomimetics (such as amphetamine, ephedrine). Additionally, products that reduce urine acidity, such as antacids, sodium bicarbonate, or acetazolamide, may also interact.

When used with medications that thin the blood or prevent clotting, such as clopidogrel or warfarin, this drug may increase bleeding risk. It's crucial to avoid other MAO inhibitors, like isocarboxazid or selegiline, as they can cause severe and potentially fatal interactions. Consult your doctor about when to start or stop this medication.

Report any use of drugs that might lead to dangerously high blood pressure when combined with this medication. These include certain herbal products (e.g., ephedra), nasal decongestants (such as phenylephrine), stimulants, and diet pills. Avoid using this product with them and seek guidance from your healthcare provider.

If you are taking azole antifungals (like itraconazole), space out their use by at least two hours from this medication. Be vigilant with over-the-counter medicines containing pain relievers like aspirin or NSAIDs (such as ibuprofen), as combining them can heighten side effects. However, if prescribed low-dose aspirin for heart protection, continue as advised unless your doctor instructs otherwise.

Inform your healthcare provider if you are using other drowsiness-inducing products, including alcohol, marijuana, antihistamines, sleep aids, muscle relaxants, or opioids. Check all medication labels for ingredients that may cause drowsiness and consult your pharmacist for safe use.

Lastly, this medication might affect certain lab tests, leading to incorrect results. Ensure that all medical professionals involved in your care are aware you are using this drug.